Type 1 and 2 neovascularization arise from the choroidal circulation and are refered to as choroidal neovascularization (CNV). Type 1 neovascularization exists beneath the Retinal pigment epithelium (RPE) while type is found between the retina and RPE, as described by Gass in 1994.
More recently, Freund et al. proposed a type 3 CNV for cases of intraretinal location …show more content…
The absence of subretinal or intraretinal exudation in repeated SD-OCT for at least 6 months is essential if CNV is to be classified as quiescent.
Traditionally,the treatment of neovascularization in AMD, generally using anti Vascular Endothelial Growth Factor (VEGF), is initiated after symptomatic exudation from neovascular lesion is confirmed by 1 or more imaging methods that include SD-OCT, FA, and ICGA.
Early detection of neovascularization lesions before the occurrence of activity signs detected with traditional multimodal imaging should result in better early monitoring of patient with intermediate AMD who are at high risk of conversion to late neovascular AMD. After all, early detection and treatment of neovascularization lesion is thought to be important in preserving as much vision as possible in these patients who convert to late neovascular AMD.
Currently , albeit it is known that one-third of eyes with occult CNV do not progress for 2 years, it is not completely established whether asymptomatic, treatment-naïve quiescent CNV may be left untreated until development of intraretinal/subretinal exudation on