Medication adherence is defined by the World Health Organization (WHO) as “the extent to which the person’s behavior corresponds with the agreed recommendations from a health care provider.”(1) In contrast, non-adherence to medication regimen results in serious health consequences such as poor clinical outcomes, morbidity and death rates increase and others unnecessary healthcare expenditure.(2)(3) Recent study found that most of the patient in hospitalization with congestive heart failure, hypertension, diabetes mellitus or hypercholesterolemia that were non-adherence to the prescribed medication compared with general population.(4)
Non-adherence to medicine can be either intentional or unintentional. Intentional non-adherence …show more content…
Other than that, these methods generally unsusceptible for the psychiatric patients and those hospitalized patients who under multidrug regimes. Therefore, these methods are more susceptible used in the patients who undergo single-dose therapy or intermittent administration.
Table 1 shows the advantages and disadvantages of various direct methods.(9)
Direct methods Advantages Disadvantages
Direct observation Accurate results Patients hinder the pills under their tongue and afterwards discard it, making the routine inspection impractical.
Measurement of drug concentration and its metabolite in the blood or urine Objective Variations in drug metabolism and “white coat adherence” can make a false impression of adherence
No information available on timing of intake
Detection of biologic marker or vital sign in the blood …show more content…
Healthcare professionals and researchers should be utilizing all the available methods to enhance the medication adherence. Medication adherence can be enhanced by emphasizing the value of patient’s regimen, simplified the regimen by decreasing the multidrug therapy, as well as customized the patient’s regimen lifestyle. This study may able to provide a general and valuable direction for the healthcare professionals to choose the most appropriate methods for their purposes and subsequently deliver efficient, customised the interventions to improve patient’s medication-taking