In an effort to identify low risk patients with acute PE for outpatient treatment, Erkens et al. (2011) conducted a research on the accuracy of PESI and sPESI by implementing a retrospective cohort study from January 1st, 2007 to December 31st, 2008 at Otawa Hospital in Canada. The authors previously assessed the safety of outpatient care for patients with acute PE in a study using discrimination criteria such as systolic blood pressure, oxygen saturation, contraindications to LMWH, or need for hospitalizations (Erkens et al., 2010). In this previous study, the authors concluded that the majority of …show more content…
This research study found that there were no deaths among the low risk patients during the three months follow up period. One hundred and fifteen (47.3%) patients treated as outpatients showed no deaths or adverse events such as bleeding. Even though low risk patients are candidates for outpatient care, this study’s outpatient group included 34 (29.6%) classified as high risk by PESI, and 54 (47.0%) classified as high risk by sPESI. From the outpatient group of 115 (47.3%), only one patient had a recurrent DVT within 30 days of follow up. The authors concluded that the two scores are accurately identifying low risk patients with acute PE who can be safely treated as outpatients (Erkens et al., 2011). However, not only low risk patients are candidates for outpatient treatment as their study showed that selective high risk patients were also treated safely and effectively …show more content…
(2011) at 19 emergency departments in Switzerland, France, Belgium and the USA concluded that certain low risk patients with PE can be safely and effectively treated in an outpatient setting. Their study included 344 patients between February, 2007 and June, 2010 among which 172 were assigned to the outpatient group and 172 to the inpatient group initially. Patients were 18 years or older, diagnosed with acute PE and low risk of death using PESI (class I and II). Both outpatient and inpatient treatment consisted in subcutaneous injection of enoxaparin 1 mg/kg (self-injection or nurse administration) and early initiation of vitamin K antagonists (warfarin, acenocoumarol, phenprocoumon or fluidione). Follow up was done at 14, 30, 60 and 90 days. Results showed that from the remaining 171 outpatients in the study, one (0.6%)