Beside PEG, some other polymers which have a linear structure such as polyglutamic acid, polysaccharide have been utilized as polymeric drug delivery carriers. Also some complexes contain of drug and macromolecule which have a hydrodynamic size range between 5–200 nm have been used as drug carriers. One of these conjugates is Abraxane®, an albumin-conjugate paclitaxel drug, that is utilized as a therapeutic agent for patients suffering from breast cancer.145 It was demonstrated that using Abraxane® caused to increase the rate of therapeutic effects and also enhance the time which required for progression of disease and survival in patients suffering from breast cancer.
