Essay on A Study On Glucagon Like Peptide

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Glucagon-like peptide-1 (GLP-1) is an incretin hormone involved in glucose regulation. Made in the intestines and released in response to the rise in glucose from eating, GLP-1 plays a critical role in glucose homeostasis by increasing insulin production and suppressing glucagon release. Additionally, GLP-1 slows gastric emptying and contributes to satiety. The combination of these factors contributes to glycemia, particularly following meals. Activity of GLP-1, much like insulin, is impaired in patients with type 2 diabetes (T2DM) (Shaikh & Goldman, 2016). However, the advent of GLP-1 receptor agonists (GLP-1 RA) to the market in 2005 provided the option to restore this function and better refine glycemic management for people with T2DM (Anderson & Trujillo, 2016). As more and more pharmacologic treatment options become available for the treatment of T2DM, an educational tool to help professionals recall key, clinically relevant facts pertaining to GLP-1 RA therapy may be of value. To that end, the attached handout was developed to provide a summary of such details for use with primary care providers and educators looking for a high level overview of the GLP-1 RA class.
According to the American Diabetes Association (ADA) standards of medical therapy and the combined consensus statement of the American Association of Clinical Endocrinologists (AACE) and American College of Endocrinology (ACE), GLP-1 RAs are an option to enhance glycemia. They may be considered as…

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