Review of “A Clinical Trial of Integra Template for Diabetic Foot Ulcer”
Summary:
Diabetic foot ulcer is happening due to complications involving the slow healing process as a result of the diabetes. The diabetic foot ulcer is cause by diabetes mellitus which increases risk for diabetic foot ulcer. (Driver et al 891) Diabetic foot ulcer can eventually lead to amputation if not treated or if it is too advanced. now there’s a way to treat foot ulcers using synthetic skin grafts. using a bilayer of silicone and collagen, it temporally covers that open area. This allows the wound to heal without the interference of constant dressings and cleanings.
Clinical were performed on patients on patient under the following inclusive criteria: “confirmed type I or type II diabetes with a hemoglobin A1c12%, patients aged 18 or older, presence of a full-thickness neuropathic ulcer located distal to the malleolus, study ulcer duration greater than 30 days, ulcer area between 1 and 12 cm2 post-debridement, and adequate vascular perfusion as defined by ankle-brachial index 0.65 and 1.2 or toe pressure >50 mmHg or TcPO2 >40 mmHg or Doppler ultrasound consistent with adequate blood flow to the affected extremity” (Driver et al 892). The main exclusion criteria included the following: “active infection including osteomyelitis, …show more content…
The hardest part to understand had to be the results. The result were mainly percentages and since this a new study there no long lasting effects listed or any other uses for the temporary graft. The cost for the graft is not listed because this was clinical. The process of making the temporary graft before clinical trials is not mention nor is the process. What makes up the bilayer is mentioned but briefly. There is also not explanation for the process for applying the graft. It’s mainly just data and statistics but that is needed on clinical report in order to prove the products is effective in
Summary:
Diabetic foot ulcer is happening due to complications involving the slow healing process as a result of the diabetes. The diabetic foot ulcer is cause by diabetes mellitus which increases risk for diabetic foot ulcer. (Driver et al 891) Diabetic foot ulcer can eventually lead to amputation if not treated or if it is too advanced. now there’s a way to treat foot ulcers using synthetic skin grafts. using a bilayer of silicone and collagen, it temporally covers that open area. This allows the wound to heal without the interference of constant dressings and cleanings.
Clinical were performed on patients on patient under the following inclusive criteria: “confirmed type I or type II diabetes with a hemoglobin A1c12%, patients aged 18 or older, presence of a full-thickness neuropathic ulcer located distal to the malleolus, study ulcer duration greater than 30 days, ulcer area between 1 and 12 cm2 post-debridement, and adequate vascular perfusion as defined by ankle-brachial index 0.65 and 1.2 or toe pressure >50 mmHg or TcPO2 >40 mmHg or Doppler ultrasound consistent with adequate blood flow to the affected extremity” (Driver et al 892). The main exclusion criteria included the following: “active infection including osteomyelitis, …show more content…
The hardest part to understand had to be the results. The result were mainly percentages and since this a new study there no long lasting effects listed or any other uses for the temporary graft. The cost for the graft is not listed because this was clinical. The process of making the temporary graft before clinical trials is not mention nor is the process. What makes up the bilayer is mentioned but briefly. There is also not explanation for the process for applying the graft. It’s mainly just data and statistics but that is needed on clinical report in order to prove the products is effective in