What are her risk factors for developing a VTE? (Identify all factors)
Answer to Question 1 The risk factors that predisposes Mrs. X to develop a venous thromboembolism (VTE) are: advanced age, malignancy (cholangiocarcinoma), trauma (multiple falls), and recent major livery surgery (Schwartz & Rote, 2014, p. 1048-1050). Patients who are in their advanced ages are at risk in developing a VTE due to slower blood flow in their veins (Schwartz & Rote, 2014, p. 1048). Additionally, malignancy, trauma and post-operative state are examples of secondary or acquired hypercoagulability, which places individuals at risk for forming a VTE (Schwartz & Rote, 2014, p. 1049-1050). Moreover, one of Mrs. X’s surgeries was an extended right hepatectomy, which can result to an overall defect in hemostasis leading to problems with clotting systems or platelet function (Schwartz & Rote, 2014, p. 1043).
Question 2
What are the age-dependent physiologic changes which occur in …show more content…
Why is therapy overlapped?
Answer to Question 4 Treatment for venous thromboembolism is comprised of a combination of anticoagulants (heparin, enoxaparin and warfarin) given at the same time to prevent further clot formation, most especially pulmonary embolism (Schreiber, 2015). Additionally, these anticoagulants are given together to prevent morbidity as well as decreasing the risk of developing postphlebitic syndrome (Schreiber, 2015). Furthermore, these medications need to be given together with warfarin until the international normalized ratio (INR) level is considered as therapeutic for a consecutive 24 hours (>2) (Schreiber, 2015).
Question 5
What are the indicators which would trigger the need to evaluate a person for the presence of hereditary thrombophilia? Does Mrs. X need to be further evaluated for a hereditary thrombophilia? Why or why not?
Answer to Question