α-Glucosidase inhibitors are saccharides that act as competitive inhibitors of enzymes needed to digest carbohydrates specifically α-glucosidase enzymes in the brush border of the small intestine. This inhibits the cleaving of di and oligosaccharides to monosaccharides, such as glucose prior to absorption. This delays the absorption of glucose and alters the release of glucose dependent intestinal hormones. Acrabose, Migltol (10) and Voglibases (11) have been extensively studied for their hypoglycemic activity as α-glucosidase inhibitors.
Natural inhibitors from dietary plants with α-amylase inhibitory activity could be used as effective therapy inthe management of
Natural inhibitors from dietary plants with α-amylase inhibitory activity could be used as effective therapy inthe management of