Van der Waals force

Name of disease Sickle Cell Disease Location 11p15.4 – chromosome 11, on short arm of chromosome, region 1, band 5, sub-band 4 Gene/locus HBB – haemoglobin subunit beta HTML reference Stumpf, A.M. (2013). Sickle cell disease Available form: http://www.omim.org/entry/603903?search=Sickle%20Cell%20Disease&highlight=cell%20sickle%20disease Frequency More than 230 000 children with sickle cell disease are born in Africa every year, which makes about 80% of the global total. In Europe estimated…

These interactions can include weak interactions such as hydrogen bonds, ionic bonds and van der Waals forces, and also covalent bonds between two cysteine amino acids called a disulfide bond (Tymoczo et al., 2013). Similar the secondary structure, the interactions available are completely determined by the types and order of amino acids in the peptide…

Abstract : Proteins are vital components of all living cells and play a critical role in almost all biological processes. Protein structure identification is a significant challenging problem in computational biology. The Protein 's three-dimensional molecular structure (i.e., tertiary structure) reflects its proper function. Therefore, the identification of protein structure is a significant step towards understanding the protein 's function which is an important task to treat diseases,…

EXPERIMENT 1 INTERMOLECULAR FORCES OF ATTRACTION Group 5 Cabale, Sheena Marie N. Hernaez, Neil Chester C. Rivera, Ian Howell D. Ronquillo, Aljon A. Venus, Mark Joven C. I. Introduction The attraction forces between molecules are called intermolecular forces. It is the non-ideal behavior of gases. On the other hand, the attraction forces within the molecule are called intramolecular forces. (Chang, 2014) There are different types of intermolecular forces. These are dipole-dipole, dipole-induced…

According to Chemguide, Chromatography is a physical method that is used to separate a mixture of chemical substances into its components, which then can be closely analyzed. All forms of chromatography share this same principle. Here, a mobile phase travels through a stationary phase, carrying the components of the mixture with it. It is possible that the mobile phase and the stationary phase have similarities or differences that affect the overall interaction between each other and the…

fischeri chDNA. Lysing the pellet of A. fischeri required the hydrogen bonds, hydrophobic interactions, and Van der Waals forces to be disrupted. This was done by the detergent sodium dodecyl sulfate (SDS), which was present in the re-suspension buffer added and created protein-lipid-detergent complexes. Proteinase K is added to digest proteins and any nucleases that…

three-dimensional structure, based on the self-recognition of its respective sequence. Covalent bonds (peptide and disulfide), hydrogen bonds, electrostatic interactions, hydrophobic interactions, and weak, nonspecific attractive and repulsive forces are kind of physical forces which related to protein structure. The component of amino acid may be distinguished based on chemical nature of side chain group at the α-carbon atom. The side chain group determine the physicochemical properties, such…

Case study 4 Even in the absence of a known drug target, a drug can be designed to perform a specific function through the testing of a variety of substituents. Through this, the biological activity of each substituent can be determined in order to create the final product in the form of a marketable drug. An example of this is oxamniquine, which is a drug that is active against schistosomes, the causative agent for schistosomiasis (Patrick, 2013, p. 305). Schistosomiasis, caused by three…

distribution. Many blending units are available which offer differing shear, convective and dispersion properties on the powder bed. Convective forces refer to large groups of particles moving in an orthogonal direction to the axis of rotation. Dispersion is random motion of particles due to collisions, usually parallel to the axis of rotation, and shear forces separate particles that may have agglomerated due to surface characteristics of the…

conformation can be transferred from a form to another by just a few kcal/mol9. The primary DNA structure is connected by strong covalent bonds while the overall 3-D folding is determined by much weaker forces including hydrogen bonds, van der Waals, electrostatic and hydrophobic interactions. These weaker forces, being comparable in order of magnitude to the average kinetic energy of molecules at physiologically relevant temperatures, account for most of the molecular interplay, structural…