Transplant rejection

Donation If one organ or tissue donor can save multiple lives, why are there not more people registered to donate? The need for organs and tissue is much greater than the number of available donors. For this reason, many individuals waiting for transplants never get a second chance at life. Organ donation is a charitable act that is free of charge, yet few people are registered as donors. Barriers such as lack of knowledge, myths and fear play a large role in donor registration. While losing a…

and many of them die waiting on their organ list. There are several approaches for addressing this problem like artificial organs, xenotransplantation, etc. But these have other limitations like expensive organ- transplant surgery, finding a donor of tissue match, risk of tissue rejection, reducing the quality of life and other side effects. Tissue engineering and regenerative medicine is a promising and potential approach for dealing with these concerns. The development…

related to the transplants. Organ shortages have…

According to Shafer, “Over the last ten years, more than 65,000 transplant candidates in the United States were removed from the waiting list because they died” (Shafer). The cause of this is the outnumbered need for organs versus the vast shortage of organs available. This may be because in 1984, the U.S. Congress enacted the National Organ Transplant Act. This was mainly to address the ethical issues revolving around the shortage of organs. This law, although regulating the donation of organs,…

Over 120,000 people in the United States are currently on the waiting list for a lifesaving organ transplant. Scientific researched has attempted to solve this dispute, unfortunately, the ethical views of society today have held us back from any scientific progression. On February 27, 2003, Congress approved a ban on reproductive cloning; stopping any hope of scientists saving our world from disease and tragic death. Restrictions on medical research are detrimental and unacceptable to the…

Xenotransplantation is the process of transplanting or grafting organs and tissue between different species. As you’re transplanting a foreign organ not from the same species as you, this has many social and biological implications. Including the fact that there’s could be new viruses and pathogens passed over between species with the potential to cause a mass epidemic and kill of many members of a species. Also this procedure although been around for a long time it hasn’t had a very high…

human organ transplant occurred in 1954, on identical twins, and was performed by Dr. Joseph Murray, who later received a nobel prize for his work in pioneering some of the most common procedures that are practiced even today. Since then, advancements in the medical field such as more effective anti-rejection drugs, and more efficient surgical tools and techniques have made leaps and hurdles in overcoming many of the initial obstacles introduced by human organ harvesting and transplants. One…

and according to the National Kidney Foundation (2015), a majority of the recipients waiting for lifesaving organs, 101,662 are kidney transplant recipients. The United States, reflected in these statistics, helps to put into perspective the need as it is seen on a global scale. The National Kidney Foundation (2015) also notes that in 2014 there were 17,105 transplants in which 11,570 were from deceased donors. Considering the number of recipients that do not find a viable donation, the…

and children currently need lifesaving organ transplants.” (Donate Life 1). That staggering number is continuously on the rise because of new diseases and, simply put, because there are just not enough organ donors to keep up with the demand for saving lives. In recent years, scientists have been working on discovering how to create a perfectly matched organ for its recipient in an effort to decrease the organ rejection rate. By decreasing the rejection rate, less organs would be needed and…

standard of care, a number of patients with CGD can still die from infection. For those patients who have an unresponsive or progressive infection and don't have a possible relative donor, their only hope is either a Matched Unrelated Donor (MUD) transplant, that has a high risk of causing death itself, or gene therapy. Hence, we would propose using gene therapy in these patients as this has less risk of causing death, however can still possibly provide a cure. Even if the corrected cells do…