Protein structure

1- Introduction Benzosuberone based compounds are important classes of biologically active compounds that attracted a great deal of interest in the medicinal chemistry due to their potent biological activities and wide range of pharmaceutical applications [1-6]. Several publications recorded that some of benzosuberone derivatives possess antipyretic, anti-inflammatory, antimicrobial, antiulcer and antitumor activities [1-6]. As an indication for the importance of the benzosuberone based…

A patient’s good nutritional status is essential for wound healing with protein deficiency contributing to poor healing rates.[90, 134, 169, 185] Skin break-down can result in a deficit of as much as 100 gm of protein in one day.[185] There is a correlation between low serum albumin and body mass index (BMI) and the development of pressure ulcers.[122] The topical application of essential fatty…

The synthesis of Aa-g-poly(MAA) involve the optimization of various reaction conditions like initiator concentration, monomer concentration, crosslinker concentration, solvent concentration and pH. After the optimization of various reaction parameters the replications were carried-out in triplicates for the reproducibility of the results and statistical of the results obtained. It was performed using the Statistical Package for Social Science (SPSS) version 10. Statistical results of the…

Skim milk delivers the high-quality protein you need for stronger bones and bigger guns. ARE CALORIES FROM FAT, PROTEIN, AND CARBS EQUAL? Scientists study how your body processes calories from different food sources. Which combo is the best for weight loss? Goat milk? If you're trying to put on muscle, you better. Whole milk was once a staple for guys who were packing away calories and moving massive amounts of iron in order to go from pencil neck to bull neck. These days we know enough to…

the endosomes, kinases and phosphatases produces and hydrolyses specific phosphoinositides which identify endocytic membranes and allow them to recruit proteins from the cytosol that are involved in vesicle trafficking and other aspects of cellular homeostasis. Lipid mediators of signaling and recognition processes work through specific protein–lipid interactions, the levels of these signaling molecules are extremely small compared with the levels of bulk membrane…

Omega-3 Fatty Acids Omega-3 fatty acids play a big role in a number of bodily functions. They are a group of polyunsaturated fatty acids and are usually found in fatty fish such as salmon, tuna and trout in the form of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) (NIH, 2017). Another type of omega-3, called alpha-linolenic acid, is found mainly in plants. Omega-3 fatty acids play a role in muscle activity, blood clotting, digestion, fertility, cell division and growth, brain…

ACR response curve for both groups Graph9: DAS28 response curves for both groups CASE STUDY 4: RITUXIMAB & ITS BIOSIMILAR Rituximab is monoclonal antibody used to reduce auto-immune disorders, transplant rejections, etc. Rituximab binds to CD20 proteins which are found on the surface of B cells and decrease the effectiveness of natural killer cells in killing these B cells. It destroys B cells and hence treat dysfunctional or excessive number of B cells. Rituximab was developed at IDEC…

FTIR analysis of the stem bark extracts of Cassia fistula has absorption bands and the wave numbers (cm-1) of the prominent peaks obtained were described in Table 2. The peak at a frequency of 3463 cm-1, 1618 cm-1, 1448.3 cm-1 and 1241.9 cm-1 were strong while the others vary from medium to weak. Discussion: Phytochemical studies revealed the presence of secondary metabolites like tannins, flavonoid, carbohydrate, saponins, glycosides and phenol in the leaf extract while tannins, flavonoids,…

The Four Spheres of Earth Before we can learn of the compositional layers and mechanical layers of the interiors of earth, we need to know some basic concept of the four spheres. As we may know the four spheres responsible for life on earth: lithosphere, atmosphere, hydrosphere and biosphere; and their interaction with each other is called Geosphere (Fig. 1.). Another sphere that isn’t included among the rest for its different property is Pedosphere. Pedosphere is basically the interaction…

Introduction: Centrifugation is a process used to separate or concentrate materials suspended in a liquid medium. It is a method used to separate molecules under the centrifugation field based on their sedimentation rate with the help of centrifugal force. It is also used to measure the physical properties of a molecule like molecular weight, density, shape, etc. If it is used for the separation of one type of materials from others is termed as preparative centrifugation and when used for…