Placebo

It is estimated that nearly 35% of the US population has metabolic syndrome1. Metabolic syndrome encompasses a cluster of disorders that increase risk of cardiovascular disease and type 2 diabetes.2 The GI tract is home to trillions of microorganisms that confer benefits to the host. Recent evidence has implicated alternations in gut microbiota composition and metabolic activity in the pathophysiology of metabolic syndrome3,4. Maintenance of gut barrier function, regulation of immune response…

adolescents type 1 subjects were treated in an outpatient setting with cinnamon, 1g/day, or an equivalent placebo for 90 days (Altschuler, 2007). During this time, A1C levels, total daily insulin use, and any adverse events were recorded and compared. This article created two distinct testing groups. One group can be clearly identified as the control group. These participants received the placebo type medication over the course of 90 days. The second group can be clearly identified as the test…

pantoprazole. The thought is that pantoprazole increases the risk of VAP, CDI, and GI bleeding in critically ill patients who are mechanically ventilated. Rates of VAP, CDI, and GI bleeding represented the dependent variable and pantoprazole and placebo represent the independent variable in this study. The two types of data collected were nominal and ratio. Researchers included ICU patients who were mechanically ventilated for more than 24 hours and who would be receiving enteral nutrition…

nintedanib twice daily, or placebo for 52 weeks. The markers for the effectiveness of nintedanib were the annual rate of decline in FVC, and the time to the first acute exacerbation (AE) – sudden worsening in pulmonary symptoms. Both INPULSIS trials showed that the annual decline in FVC was appreciably less in the treatment groups than in the placebo groups. In INPULSIS-1, the rate of FVC decline was 114.7 ml/year in the nintedanib group, while it was 239.9 ml/year in the placebo group. In…

It was a one week, double blind, randomized, placebo controlled study that took place in India. They tested 62 total chronic pancreatitis/pancreatic exocrine insufficiency patients over the age of 18, with 28 of them having the placebo, 34 with Creon. Each patient was given two Creon 40000 capsules (this strength is unavailable as of 2015) before their main meal and one capsule before snacks. The placebo group received placebo group received placebo capsules instead of the…

hoped to improve the quality of life which included a longer sleeping time and ease of being able to go to sleep when tired. Placebos of 1-3 mg where given and chosen as an adequate amount to avoid being too little or too much drug for the patient in comparison to the placebo. Too little of the drug could not be an adequate amount to measure a difference between the placebo and too much of the drug could have induced a sleepiness effect on the patient during hours when they were not supposed to…

clinical trials. Volunteers will be asked to record how they felt after taking PainGo2 to check for side effects, and to see if is safe and effective before conducting bigger clinical trials with the optimum dose of the drug. c) What is a placebo? A placebo is a substance or other kind of treatment that looks just like a regular…

The oral alogliptin can work as monotherapy or in combination with other oral antihyperglycaemic agents in the treatment. The clinical subjects in these studies receiving alogliptin once a day, and all the studies are randomized, double-blind and placebo-controlled studies, which following Good Clinical Practice and ethical standards for studies in humans. Evidence for clinical effectiveness Clinical phase I study…

About 400,00 individuals are affected by multiple sclerosis (MS) in the United States and about 2.3 million people worldwide (National Multiple Sclerosis Society, 2002). The majority of symptoms commence between ages 20 and 40, with greater risk for women to be twice as likely to develop the disease (National Institute of Health, 2014). The exact cause of MS is unknown but there research shows there are geographic (people who live further from the equator), genetic, race (Northern European…

Notably, Kinesio tape is made up of thin cotton and acrylic-acid-consisting porous fabric. As such, Kinesio tape is a unique non-latex adhesive patch. Its function in pain reduction can be explained on the bases that once it adheres to the VMO muscle of a patient with anterior knee pain, proprioception input increases hence facilitating muscle contraction (35). Additionally, the tape is applied over the iliotibial band, tensor fasciae latae and VL muscle to hinder tension of the muscles as well…