Peripheral neuropathy

pain whether based on an injury or a result of a form of dysfunction from the nervous system is still a condition which better treatment options are still being researched. Neuropathic pain can even be divided further into peripheral and central neuropathic pain. While peripheral pain may result from a disease, a more central neuropathic pain may result from damage to brain or spinal cord. [] Despite numerous medications in the market and therapy treatments which patients endure, neuropathic…

find it challenging to administer the available outpatient cognitive assessment tools, which require functional vision to diagnose dementia. Case: A 62-year-old African-American woman with history of hypertension, type-2 diabetes mellitus, peripheral neuropathy and legal blindness from Diabetic retinopathy presented for a routine evaluation. Patient was accompanied by her husband who expressed concerns that for the past six months, patient was being forgetful of instructions and had trouble…

• Vascular lesions (abnormalities in the blood vessels) pressing against the brain or spinal cord Disorders affecting the peripheral nerves, such as: • Nerve entrapment syndromes, like carpal tunnel syndrome, where peripheral nerves are damaged, causing paresthesia and pain. • Complications of chronic disease, such as diabetes and atherosclerosis, which cause neuropathy due to poor circulation • Malnutrition and vitamin deficiencies • Disorders of metabolism, such as thyroid gland disease •…

smoking and dyslipidemia. In addition to heart disease a patient can have peripheral vascular disease, which causes lack of circulation to the brain and heart. The most common sign of this disease is intermittent claudication. Neuropathy can be a cause of this due to the lack of the circulation in the feet, which cause foot injury; this is the main complication leading to hospitalization. According to ATI PowerPoint, “sensory neuropathy, ischemia and infection are the leading cause of food…

synthesized drug called Thalidomide, it was introduced as an effective sedative used to treat the symptoms of morning sickness in pregnant women. It was soon discovered that Thalidomide was in fact a potent teratogen* that could cause dysmelia, peripheral neuropathy and in some cases, premature termination of pregnancy; it was because of these reasons that thalidomide was removed from the world’s pharmacy shelfs in the early 1960’s. Today, almost 62 years after its original discovery,…

abnormalities, and loss of reflexes. Guillain-Barré syndrome can be divided into 4 major clinically distinct forms: acute inflammatory demyelinating polyradiculoneuropathy (AIDP), the Miller Fisher syndrome (MFS), acute motor axonal neuropathy (AMAN), and acute sensorimotor axonal neuropathy (AMSAN). There are a number of potential triggers that in genetically susceptible individuals can cause this disease such as surgery, vaccinations, or infections with Campylobacter jejuni, cytomegalovirus,…

Sensory disturbance such as numbness and tingling sensation in the hands is extremely common which starts start in the fingertips, are confined to the hand, and occur in a nonradicular distribution and is often misdiagnosed as peripheral neuropathy sometime carpal tunnel syndrome as well. Clumsiness of the hands leads an weakness in carrying out fine motor movements. There may be marked wasting of the intrinsic hand muscles of hands. Ono et al. described two specific signs of the myelopathy…

that affects the peripheral nerves” (NINDS). They still consider this disease to being rare in the United states. The estimated amount of people who are diagnosed is fewer than 175,00 a year and the worldwide estimate is around 2.5 million. Of course, this number can be much more. National Institute of Neurological Disorders and Stroke has said that “CMT is one of the most common inherited neurological disorders” (NINDS). CMT is also known as Hereditary Motor and Sensory Neuropathy is HMSN for…

this disorder also have very overt autonomic symptoms, so they tend to show a lot of their actions that are supposed to be involuntary. Congenital Insensitivity is a genetically transmitted disorder, also known as hereditary sensory and autonomic neuropathy type four. When both parents carry the gene mutation, there is a 25% chance the child will inherit the disorder during the pregnancy of the mother. Congenital insensitivity is causes by a mutation in the SCN9A gene, and even the slightest…

While we did not have enough participants in the pilot study to perform any inferential statistics, we feel the knowledge and experience gained is important for informing the full study. Therefore, we have revised the protocol. Below is the proposed plan for the full study. Objectives The overall objective of the full study is to determine if ALL survivors are at increased risk for postural control deficits compared to healthy age-matched individuals. The specific aims and hypotheses for this…