Paget's disease of bone

-The Skeletal System 1. Explain how and when bone is remodeled. Include the cells and hormones involved in the process. • Bone remodeling is essentially a lifelong process. The mature bone tissue is removed and replaced the new bone tissue. This promotes healthy bones and can also reshape the bones from injuries like fractures. Osteoblasts secrete new bone tissue while osteoclasts break down the old bone tissues. The body signals the correct amount of growth through parathyroid and growth…

Hip replacement surgery is performed to replace the hip joint by the prosthetic implant. The replacement can be either partial or total, based on the specifications of the condition of the patient. The surgery is performed for the patients, who suffer from the conditions like arthritis pain or treatment for the hip fracture and for the replacement of the femoral head and acetabulum head. And in the place of these heads, a new socket or a ball will be placed as a prosthesis or an implant. Hip…

Erdheim-Chester Disease is a fatal and an extremely rare disorder that can affect many different organs of the body. It is characterized by excessive production and accumulation of specific cells whose normal function is to fight infections. These cells, which are called histiocytes, infiltrate the loose connective tissue (lipid-laden macrophages) of the body. As a result this tissue becomes thickened, dense and fibrotic. Multiple different organs can be affected. Unless successful…

human body contains a bunch of different systems, and it has many divisions within the systems. Organs, tissues, bones, joints, and cartilage are just a few things that are the genetic makeup of the actually human skeletal system. The human skeletal system is very diverse but unique at the same time. Bones are responsible for playing a major role in how our body is made up and functions. A bone is a rigid organ in which it contains living and evolving tissue that has various particular functions…

Neoplastic disease refers to excessive cell division, there are many things that can cause the formation of atypical bodies of tissue also known as neoplasms. A neoplasm can occur anywhere in the body and it is known as a tumor. Breast cancer is a neoplastic disease that starts in the tissues of the breast. Over the course of a life time, 1 in 8 women will be diagnosed with breast cancer. Just like many other types of cancers, there are many risk factors that unfortunately cannot be changed no…

Micro-fracture consolidation can be treated with bone remodeling, and the adaptation of skeleton is applied to “calcium homeostasis” and to mechanical use. The bone remodeling involves the bone resorption regarding to osteoclasts and bone formation relating to osteoblasts. Regular bone-related diseases including “bone-metastasized cancers”, Paget’s disease, multiple myeloma, and osteoporosis are caused by the disproportion between the resorption and formation processes. The increased…

down the digestive tract. This type of muscle is also autonomous. The third type of muscle is skeletal muscle. Skeletal muscle is the only type of muscle that is not autonomous and is controlled by the nervous system. Skeletal muscle works with bones to allow for movement. Some known threats against the muscular system include myotonia, which causes unwanted movements in voluntary muscle, mitochondrial myopathies, which includes damage to the mitochondria of muscle cells, and myofascial…

anti-proliferative activites has been studied in vitro; however its effects on osteoclast differentiation have not been demonstrated. In this study, CTXA was found to suppress RANKL-induced osteoclastogenesis, actin ring formation, and bone resorption in RAW 264.7 cell lines and mouse bone marrow monocytes (BMMs). CTXA significantly inhibited the JNK/mitogen-activated protein kinase (MAPK) signaling pathway without affecting ERK and p38 signaling in RANKL-stimulated RAW 264.7 cells and BMMs.…

Midwives have been helping women in pregnancy and birth for a very long time. The number of births, in which a midwife assists, has dwindled in the past years but is slowly growing. According to the Aamerican College of Nurse Midwives 7.9% of births in the United States were assisted by midwives. Midwifery is an intense but rewarding job that has multiple necessary qualifications since midwives must give prenatal care, assist at births, and give a small amount of postpartum care. Midwives…

controlling our own habits and the actions we do. Diseases are one of the major causes of many deaths. These diseases can cause from many factors: airborne, infectious, non-communicable, food borne, and last but not least our lifestyle. Cancer is one type of the diseases that can cause death.…