Nicotinic acetylcholine receptor

Inclusion Body Myositis is a neuro-muscular disease affecting people over fifty, mostly males, is characterized by progressive muscle weakness and atrophy in key muscles in the arms (forearm flexors) and the legs (quadriceps), resulting in severe disability. IBM is generally a slowly progressive disease and life expectancy isn’t significantly affected. Ted was diagnosed with IBM in 2012 when he was 68 years old, but his muscle biopsy showed that he has had it 10 to 15 years prior to the…

effect of competitive inhibition on acetylcholine and its relationship with the production of muscle contraction. In formality, tubocurare was the neurotoxin used in this lab exercise, and it is a form of a competitive inhibitor against acetylcholine. The tubocurare ions bind to the specific active site of acetylcholine receptors on the motor end plates called Nicotine Acetylcholine Receptors. Consequently, tubocurare diminishes the available outlets for acetylcholine to initiate depolarization…

Morgellons disease is an interesting disease that is very rare and often hard to diagnose correctly. This particular disease is very hard to clarify. The symptoms can be different from varying patients. However, general symptoms include crawling senses under the skin, itching, black dots in the skin, thread-like fibers coming from the skin or underneath the skin, joint pain, trouble sleeping, panic attacks, memory loss and skin rashes. Not all patients have these symptoms but the two that almost…

Aricept is a medication, which can help to decrease the symptoms of Alzheimer’s disease by increasing the level of chemical in the brain called acetylcholine messenger (Health Canada, 2015). Medication does not treat Alzheimer’s disease; however, it helps patients to progress their thinking, memory and the capability to do their simple everyday jobs, which reduces the signs of Alzheimer’s disease (Aricept, 2016). Aricept is a medication that helps to stabilize dementia that is associated with…

Duchenne Muscular Dystrophy The body is like one huge scale that needs constant conservation to maintain balance for a stable state of survival. Homeostasis is the component that helps the body maintain balance. There are four core principles that help homeostasis keep balance which are, feedback loops, relationship of structure and function, gradients, and cell to cell communication. “Muscular homeostasis is cell to cell communication that coordinate their functions and maintain homeostasis…

This study analyzed the differences and the relationships of the isolated sciatic nerve in regards to the compound action potential and the neuromuscular junction stimulations of the Rana pipens gastrocnemius. A total of five exercises were used to identify the effects on the stimulation of the sciatic nerve and the gastrocnemius. A dissection for both labs were performed to isolate the nerve and to isolate the gastrocnemius. Both experiments used LabChart to perform various stimulations on the…

Figure 1. An EMG Tracing of Triceps and Biceps Muscles Co-activation. EMG signal produces an electrical activity of the muscle fibers active at a moment time. The electrical activity is measured in millivolts per milliseconds. The top channel shows the bicep EMG, while the bottom EMG correlates to the triceps contraction traces. Shown on the top graph, there are two periods of bicep activation, each last approximately 1.5ms. When the biceps are activated, it produces increasing amplitude peaks,…

For this lab report the class goal was to figure out if our dominate hand is stronger than our non-dominate hand. There are a few factors that come into play when measuring this, the first thing that is important to know is what a muscle is and how it works. According to Medicine net a muscle is “the tissue of the body which primarily functions as a source of power.” A muscle is also used for movement and keeping body parts in their right positions. There are 3 different types of muscles,…

are a great deal of muscles and nerves in the forearm. When a nerve impulse transmission to synaptosomes induced depolarization, allows calcium ions to enter the cell membrane, the synaptic vesicles move forward and release acetylcholine (ACH). ACH combined with membrane receptors on the endplate cause electronic potentials, potassium and sodium ions exchanging start to spread both sides of muscle cell membrane to form the action potentials, and long with the cell membrane so that both sides of…

Understanding the anatomical map of structures such as the phrenic nerve is vital for medical treatments. G.S. Muller Botha mapped the phrenic nerve and described her findings in The Anatomy of the Phrenic Nerve Termination and the Motor Innervation of the Diaphragm. Sleep apnea is a common disorder caused by under stimulation of the diaphragm from the phrenic nerve, O. Oldenburg and team described alternative treatments for the apnea in Effects of unilateral phrenic nerve stimulation on tidal…