Neuromuscular junction

Dry needling involves the insertion of needles into tender points in the body without the injection of any substance. It is used to treat painful musculoskeletal disorders. The more common approaches, which are best supported by research, target myofascial trigger points. Dry needling and trigger point theory emerged from the use of injections of anesthetic to treat painful musculoskeletal conditions. Myofascial pain, or “trigger point” pain is often the source of chronic pain and dysfunction,…

Tessa Jones Professor Pericone M.S. Human Anatomy & Physiology I – BIOL 130-03 20 November 2017 The Stiff Truth About Rigor Mortis Growing up, I have always been intrigued by murder mysteries. My favorite shows consisted of Criminal Minds, CSI, and NCIS. From watching these shows episode after episode, I have become familiarized with the term “Rigor Mortis”. Rigor Mortis is referred to as the third stage of death, where the muscles in the body contract leaving the body “stiff” for a period of…

hands, fingers, legs and neck. Myasthenia Gravis is a rare disease that may be difficult to diagnose. Myasthenia Gravis occurs when there is an error in the transmission of the nerve impulses, therefore when there is an interruption at the neuromuscular junction, where the nerve cells connect to the muscles. Neurotransmitters are chemicals that the brain cells use to communication information. Nerve endings typically release a…

consistent patterns of the ECG which occurs in regular intervals. 2. This delay is primarily caused by the atrioventricular node (A-V node) and the adjacent conductive fibres. Conduction in cardiac muscle is hindered by the decreasing number of gap junctions along the pathway of conduction which creates a resistance against the conduction of excitatory ions, i.e. Ca2+, from one fibre to another. This ensures that the atria completely empty the blood into the ventricles before ventricular…

I really found the chapters challenging this week! Every week, I am more amazed at how complex our bodies are. The amount of different systems, and processes needed to maintain homeostasis constantly. The complex way the body heals itself, is amazing as well. The first year of our lives, our skeletal system replaces itself 100 percent. The rest of our lives, it slows down to replacing about ten percent of itself yearly. That is a huge difference!! Bones remodel themselves in a lifelong process…

to Impaired spontaneous Ventilation. MG starts from the head and moves downward to the toes and is an autoimmune disorder where acetylcholine receptors are blocked by antibodies. Acetylcholine normally causes an excitatory effect at the neuromuscular junctions. The client will usually seek a physician's help because they…

The brain or spinal cord sends an action potential to the muscle. 2. The impulse travels down the motor neuron and reaches a neuromuscular junction where it releases acetylcholine, which triggers the action potential in the muscle. 3. The action potential travels through the sarcolemma and down the T-tubules surrounding the myofibrils. 4. As the impulse passes through the T-tubules, it…

If you asked me a year and a half ago what I wanted my vocation to be, I would have promptly blurted out: “Forensic pathologist.” If you ask me now, I will respond with: “I don’t know, it may change, but I’ve got an idea.” While my interests remain within the world of science, it’s still an entire world nonetheless. I have opened myself up to exploring new career paths within this world because of one factor during the end of my sophomore year of high school—exploring the unknown. I did not…

The muscular system is the system of the body that contains smooth, skeletal, and cardiac muscle tissue. This system contains a variety of functions including movement of the body and of materials throughout the body, maintenance of posture, and heat production. Muscles are the only tissue in the body that have the ability to contract and therefore move the other parts of the body. The muscular system is important because without it, life would completely stop. Muscles produce not only…

Syntaxin, SNAP 25 and Synaptobrevin. The seven different serotypes of botulinum toxin have affinities for different SNARE proteins. These SNARE proteins are vital for the synaptic vesicles filled with Acetylcholine to dock to the terminal of the neuromuscular junction when an impulse is received. The vesicles then fuse and release the Acetylcholine into the synaptic cleft. Acetylcholine binds to ligand-gated ion channels, opening them and initiating muscle contraction. By cleaving the SNARE…