Megaloblastic anemia

Pernicious anemia is a form of anemia discovered in the mid-19th century, commonly credited to the UK physician Thomas Addison for work in 1849, despite the facts that he was neither the first to describe nor name it (Lichtman et al. 563). A clinician by the name of Biermer officially named the disease, and it has been researched in depth while treated in various ways since this time. This work examines various aspects of pernicious anemia, considering fundamental traits of the disorder, mechanisms, symptoms, treatment, and other clinical work. Overall it is evident that while significant progress has been made in understanding the disease, additional work and development is required to better understand and treat it. Pernicious Anemia According to USNLM (par. 1), “anemia is a condition in which the body does not have enough healthy red blood…

Pernicious anemia is also known as Biermer’s disease and Addisonian anemia. The first clinical description of pernicious anemia, which is one of the known causes of megaloblastic anemia, has been attributed to Tomas Addison in 1849. One way pernicious can develop is the loss of gastric parietal cells, which are responsible for the secretion of intrinsic factor, a protein necessary for absorption of vitamin B12 in the ileum. Vitamin B12 helps the body make healthy red blood cells and helps keep…

would affect her electrolyte levels. CARDIOPULMONARY/OXYGENATION Age specific variation of growth and development. The Health Promotion Strategies Through the Lifespan, states for adolescents the average blood pressure ranges from one hundred to one hundred and twenty over fifty to seventy. Pulse ranges from sixty to sixty eight beats per minute. Respirations average from sixteen to eighteen breaths per minute. (Murry, Zentner, Yakimo, pg.445, 2009) Health history and subjective data…

First, hematotoxicity is the study of blood and blood-forming tissues as a target organ for drugs or different chemicals. It is the toxic effect that the substance has on the properties or components of blood. Additionally, other factors to include when determining toxicity are stress, exercise, and ionizing radiation. Furthermore, blood and hematopoietic tissue are target organs for scrutiny and the study in preclinical and clinical safety evaluations. There are several methods that…

Thalassemia is known to be an inherited genetic blood disorder that results in mild to severe anemia due to the abnormal formation of hemoglobin. Thalassemia is inherited by either one or both parents. A mutation in either chromosome 11 (Deisserot et al, 1978) effect the synthesis of beta hemoglobin, whereas a mutation on chromosome 16 affect the synthesis of alpha hemoglobin(Deisserot et al, 1977). Hemoglobin is a tetramer made of two alpha chains and two beta chains (Cao et al, 2010). The…

anaemia. Vitamin C promotes absorption is iron and for it vitamin C rich foods like lemon * Supplementation of iron and folate tablets - Supplementary feeding through ICDS programme for pregnant women, lactating mothers and young children as also distribution of IFA supplements to women, adolescent girls and children have not met with much success. Nutritional iron deficiency is common in developing nations. An estimated two-thirds of children and of women of childbearing age in most developing…

Arterial diameter, diffusion distance, and proportion of wrapping were manually measured for vessel pairs that were matched in both the light micrographs and micro-CT images in a blinded manner. Artery-vein pairs were identified, matched in both micro-CT and light microscopy images, and then labelled. Measurements were first made for the artery-vein pairs in the light micrographs. Then, measurements were made for the artery-vein pairs in the micro-CT images. A total of 25 vessel pairs were…

Death is a supernatural physical loss of an individual’s soul. A vast majority of individuals experience death in different ways. In other words, death can come slowly and painfully, or quickly and painlessly. Three years ago, my cousin, Ollie Green, died of sickle cell anemia. Ollie’s life could be described as the process of baking a cake. When I received the news of his death, my perfectly prepared cake was now burnt and destroyed. A correlation of contradicting emotions suppressed my mind.…

The average life expectancy for females with sickle cell anemia is 48 years. Since both my client’s parents has the sickle cell gene, 25 percent of infants with both parents having the gene will inherit it. Statistics showed that the intake of vitamins E and D, folate, calcium, and fiber as %DRI was lower for children of all ages; also, they are the nutrients of most concern. The Intake of vitamin C, protein, vitamin B-12, riboflavin, and magnesium becomes lower and lower with age. Infants…

In other words, anemia may be stimulated by malnutrition, family history of anemia, alcoholism, strict vegan diet, intestinal disorders that affect nutrient absorption of the body, exposure to toxic chemicals, anemia in women during childbearing years, race, and chronic diseases. Signs and Symptoms Fatigue and weakness are the signs of mild anemia. The other signs include pasty or sallow complexion or no color in the palms, gums, nails beds, and lining of eyelids. People who are weak, get…