Liver disease

hepatic function and to determine the changes in carvedilol pharmacokinetics in the setting of liver fibrosis. Various tests were completed in rats to measure hepatic blood flow, as well as synthetic and metabolic capacity. Three of the four main components of PK were described in the introduction of the paper. Oral absorption of carvedilol is both rapid and complete. Extensive metabolism occurs in the liver. Elimination of the drug occurs via several mechanisms, which are explained in greater…

bile is secreted from the liver and drained through the smile bile bones called canaliculli. They collect into the heapatic ducts, which then collect in the common heapatic ducts. The heapatic ducts join by the cystic duct to create the common bile duct. These would run from the liver to the duodenum, which would be the first section of the small intestine. However, not all the bile flows directly into the duodenum. About half of the bile that is produced by the liver is stored in the…

Gaucher’s disease if you haven’t heard of it already is a metabolic disorder one of the most common for lysosomal diseases and it is inherited. It can also be carried and not known by the individual, a carrier only has a single gene mutation that is associated with the disorder. In order actually have Gaucher’s diseases an individual must have two mutations in the GBA gene; one from each parent. Gaucher’s is when the metabolism and storage of fats is irregular; this can be quite harmful due to…

Hepatitis Delta Virus, more common known as Hepatitis D or HBV, was discovered in 1977. An Italian doctor, Mario Rizzetto, noticed an abnormality in the cells of hepatitis B (HBV) patients. The new antigen in the liver was first thought to come from HBV; however after more research it was discovered that it was its own virus. Hepatitis D is a virus affecting many around the world. (Chhibber and Shanh, 2005) There are two different kinds of the virus that can be acquired, co-infection and super…

Crohn’s disease is a recurrent infection that affects primarily the digestive system. It involves inflammation of the intestines both the small and the large intestines. It affects only the digestive tract of human beings. To enable one understand Crohn's disease, it is important to understand the whole digestive system and how it works in the process of digestion. The digestive system is made up of the digestive tract, the pancreases, liver and the gall bladder. Track refers to hollow organs…

prevent potassium depletion, which can occur when taking other types of diuretics. Dandelion is valued as a blood purifier and liver tonic, and is used to treat a variety of liver conditions including hepatitis and cirrhosis. It is also beneficial to the spleen, stomach, pancreas and kidneys. Dandelion may be useful to help relieve stiffness in those with joint diseases such as arthritis and…

Statins represent a class of cholesterol-lowering agents used for the treatment of dyslipidemia (abnormal amount of lipids) and the reduction of atherosclerotic cardiovascular disease risk. Their broad and potent effects on the lipid profile and cholesterol-independent pleiotropic cardioprotective effects positioned them among the most prescribed medications worldwide. Statins were introduced in the late 1980s and early 1990s as a novel group of cholesterol-lowering drugs in attempt to offer…

administered. At the end of phase one, the safe dosage and the best route to administer drug will be set. Phase two is similar to phase one. The difference is that in this phase, the researchers recruit a small group of people who has suffered from the disease which the drug is supposed to effect on. At the end of phase two, the effective dosage and its interval will be determined. In phase three, the researchers…

Hepatitis A is a virus that attacks the liver and makes it inflammed. It is a mild- severe illness Hepatitis A can cause fever, nausea, diarrhea, jaundice, fatigue, abdominal pain and loss of appetite. Symptoms of Hepatitis A can occur two to seven weeks after coming in contact with the virus…

Hepatitis C virus (HCV) is an RNA positive virus. HCV causes both acute and chronic hepatitis C, which can lead to liver disease. HCV infects 130 to 150 million people worldwide. HCV is spread by blood transfusions [1]. Unfortunately, no vaccine for HCV is available because of the fact that the HCV life cycle has not been reproduced in cell culture, which resulted in slowing research progress of this human virus [2]. On the other hand, 15-20% of chronic hepatitis C patients achieve a sustained…