Liver disease

Hepatocellular carcinoma (HCC), the most common primary liver cancer, is one of the dreaded complications of chronic liver disease. Recent experimental and clinical studies have revealed the pivotal role played by the alteration of gut-liver axis in the onset of chronic liver diseases, including HCC. Altered gut microbiota and endotoxemia are increasingly recognized as critical components in promoting the procession of chronic liver diseases and the development of HCC. Probiotics have been…

AND PREVETION OF HEPATIC CIRRHOSIS AND FIBROSIS INTRODUCTION Liver cirrhosis is a common outcome in clinical progressions of all chronic liver diseases, distinguished by substitution of tissues of the liver by fibrous (scar) tissues. Regenerative nodules - lumps that appear in a bid to repair the damaged tissues – also replace the liver tissues, leading to an alteration of the liver structure to into structurally abnormal nodules. Liver fibrosis is as a resultant effect of the propagation of the…

underlying health conditions, and patient immunity. Several clinical studies have noticed a link between lipid metabolism and systemic inflammation. In septic shock, patients can have an abnormal lipid profile which may be due to de novo lipogenesis.¹ The liver…

Cirrhosis of the Liver The Liver is an organ that is in the human body. The liver plays an important role in the human anatomy. The Liver is located below the diaphragm in the upper right quadrant. It is the second largest organ in the human body. The Liver is about the size of a football and weighs around 3 to 4 pounds. Some of its main purpose is to metabolize most of the nutrients that enters the body and absorbers by the intestine. Some of the Liver’s main function is to help the body get…

Background Primary Biliary Cirrhosis (PBC), also known as an autoimmune liver disease, damages the bile ducts within the liver. In the body the ducts play an important part in digestion because they carry fluid away from the liver. Over time the pressure builds up from the fluid causes the cirrhosis of the liver. The destruction of the bile ducts can have early symptoms such as fatigue, itchy skin, and jaundice. Prevalence/Incidence Primary Biliary Cirrhosis is mostly found in women…

Liver failure, caused by things such as hepatitis and cirrhosis, leads to an array of symptoms including cardiorespiratory insufficiency (hepatopulmonary syndrome; HPS) and renal failure (hepatorenal syndrome; HRS). Disregarding the cause of liver failure itself, discuss the development of both of these symptoms. Hepatopulmonary Syndrome Figure 1: Blood Flow in Normal Conditions and Hepatopulmonary Syndrome (Grace & Angus, 2013). Figure 1 (above) shows the blood flow in a normal patient (top),…

hepatitis B viral (HBV) infection, chronic hepatitis C virus (HCV) infection, cirrhosis of any cause including environmental toxins, alcohol abuse, nonalcoholic fatty liver disease, hereditary hemochromatosis or alpha-1 antitrypsin deficiency among others. There has been significant increase in the rate of HBV- and HCV-related HCC[1]. Liver cirrhosis is the most important pre-malignant lesion of HCC, but HCC can occur in non-cirrhotic patients too, with the predominant risk factor being HBV…

Some people have no symptoms then later realize they have a disease known as hepatitis C. It is an infection of the liver, the virus comes in many forms. Here in the U.S the most common form is type 1. Also the most common way of getting it is by the use of unsafe practices for example injections and improper sterilization. According to the article What Is Hepatitis C, about 3.5 million people have the disease. Knowing the signs and symptoms, if there are any cures, how can it be prevented, and…

Numerous toxicants have some sought of an affect the human body. These come in a variety of ways, but in the process more often the most affected happens to be the respiratory, immune system, along with the liver. These are primary systems within the body that are vital in order for each of us function and survive. Therefore if by some chance these if any of these systems/organ manage to fail, the likely outcome would be that a person becomes very ill. While technology has come a long way, as…

What is HELLP Syndrome? HELLP syndrome is a life-threatening liver disorder that occurs during pregnancy and postpartum. It is characterized by hemolysis (destruction of red blood cells), elevated liver enzymes (which indicate liver damage), and low platelet count. According to Olds’Maternal-Newborn Nursing Tenth Edition, HELLP is usually related to preeclampsia and about 10% to 20% of women who have severe preeclampsia develop HELLP prior to 37 weeks’ gestation 50% of the time. However it may…