Hyperuricemia

Treatment of Gout and Rheumatic Gout”. ³One of his ten propositions in this book stated firmly and clearly that the gout inflammation was caused by the deposited urate of soda (uric acid), and no other that an excess of uric acid (today we’d call it hyperuricemia) led to crystallization and…

Estimation of Plasma urea, uric acid and Creatinine in plasma of control and experimental rats Urea, creatinine and uric acid were assayed in plasma using standard kits supplied from Agappe Diagnostics Ltd., Kerala, India and the results expressed as mg/dl. 3.4.1 Effect of Kombucha on urea, creatinine and uric acid in control and experimental rats As shown in Table 3.4.1, STZ induced diabetic hyperglycemia causes the significant elevation of plasma levels of urea, uric acid and creatinine…

Introduction: Heart Failure (HF) is a complex clinical syndrome that affects the structural and functional capacity of the ventricle to load or expel blood. According to Ferri (2016, p. 576), the principal symptoms of HF are dyspnea and fatigue which can significantly reduce an individual's exercise tolerance. Due to the various signs and symptoms associated with HF, multiple pharmacotherapies including ACE inhibitors, beta-blockers, calcium channel inotropic agents, and diuretics has been…

Gene-environment interaction and its effect on obesity disease Unlike what is usually portrayed on media, obesity is not just a problem of unhealthy lifestyle but in fact influenced by genetic factor as well. Genetic factor is believed to attribute 40 – 70% in the development of obesity (Shawky & Sadik, 2012). In other words, environment, genotypes and the association of these two factors play roles in the phenotype expression, which, in this case, is obesity. With regards to environmental…

Lesch- Nyhan Syndrome Kayla Lester Virginia Western Community College Abstract Lesch-Nyhan syndrome is a genetic disease that is inherited from an offspring’s mother. A patient is typically diagnosed between the ages of three to six months with Nyhan’s syndrome. Since this is such a rare disease there is only a one in three hundred and eighty thousand chance a person would be diagnosed with this disease. It is equally seen in all ethnic group but it is more likely for males than females due to…

Annie, 40years old female has been admitted in Emergency department with chief complain of excruciating increasing pain in her big toe for the last two days. In addition to this, she also stated that she has not sleep for the last two days. On examination her toe appears red and swollen and warm to touch. Also, during palpation throbbing pulsation can be felt. According to Annie she cannot bear weight on her right foot. According to past medical history Anne has been diagnosed with gout. Her…

According to Schouten et al (2008), sepsis involves the activation of the coagulation cascade coupled with down-regulation of anticoagulation and fibrinolysis. An intricate link between inflammation and coagulation exists within the body (Neligan, 2006). When a pathogen is present in the bloodstream or when tissue injury occurs, an inflammatory response occurs. The response causes a stimulation of the immune system to produce interleukin-1 (IL-1), interleukin-6 (IL-6) and tumor necrosis…