Hyperuricemia

According to the Center for Disease Control, it is estimated that there are about 6 million Americans who are affected by Gout. Gout is a form of inflammatory arthritis and can occur in the body when there is too much uric acid in the blood stream (Center for Disease Control, 2016). Uric acid can begin to form when high amounts of purines found in food begin to breakdown and form crystals of uric acid that start to build up in the connective tissues and joint space, this condition is also known as hyperuricemia (CDC, 2016). When there is too much production of uric acid and not enough excretion that is when hyperuricemia can occur (CDC, 2016). Hyperuricemia is not Gout however; it is a precursor to Gout (CDC, 2016). Gout can be a very…

Gout has been identified as early as 2640 BC by the ancient Egyptians, with famous suffers such as composer Ludwig van Beethoven, diplomate Benjamin Franklin, astronomer Galileo Galilei, and physicist Isaac Newton and known as the disease of kings due to prevalence of an indulgent lifestyle, such as consumption of alcohol, fructose-sweetened drinks, meat and other rich foods lead to risk factors of gout. Gout is caused by an excesses amount of uric acid being deposited in needle-like structures…

common inflammatory arthopathy in men older than 40 years (Bolognia, First Consult). Gout is a deposition disease of metabolic origin caused by supersaturation of monosodium urate, or hyperuricemia. Needle-like crystals are deposited into joints, connective tissue, and the kidneys. This deposition may lead to various clinical sequelae such as arthritis, tophi, and acute kidney injury (Bolognia). Gout can transition through many phases including asymptomatic, acute, and chronic disease (3).…

Gout is a sort of metabolic arthritis which is an extremely painful disease. The disease is caused by the congenital disorder of the uric acid metabolism. Our body produces the uric acid but the body gets rid of the uric acid through the system. However, some problems in the kidneys or the accumulation of too much uric acid in the body cannot be flashed out of the body through the system and they start to form the uric acid crystals in the body. The crystals start to be deposited in the joints,…

5 Things to Avoid to Prevent Gout Gout is a general term that describes a wide variety of conditions that are caused by uric acid buildup. Usually, this affects the feet. Gout is characterized by pain and swelling in the joints of the feet, particularly on the big toe. Gout attacks or sudden intense pains can create the illusion of the feet being on fire. A wide variety of factors play a significant role in causing gout. Drinking too much alcohol and a couple of medical conditions can result…

This Effective Natural Treatment Will Help You to Get Rid of Gout Forever Gout, a form of arthritis, is often ignored by those who have not suffered from this complicated disease that is quite unbearable. When uric acids build up in the blood gout appears. This build ups come from the breakdown of the waste processed by the kidneys and dissolved in the blood. When the kidneys are not able to get rid of the uric acid, it crystallizes and builds up waste products in the joints. This condition…

When patient presents with gout attacks most often patients present with complaints of severe pain, erythema and swelling of the particular joint. As a result, during the clinical evaluation phase it is important to consider a broad differential diagnosis because many disorders can present with similar clinical features. Pseudo gout, septic arthritis, rheumatoid arthritis, osteoarthritis, cellulitis, acute fracture should be considered as differential diagnosis for patients with above mentioned…

Phosphoribose is then, synthesized by synthase and is now PRPP (or phosphoribosyl pyrophosphate). The PRPP is then, converted to the nucleotide IMP (or inosine monophosphate). The nucleotide IMP can then, be converted to both purines AMP (or adenosine monophosphate) and GMP (guanine monophosphate). Both purines AMP and GMP are further broken down by xanthine oxidase to make uric acid. However, individuals with hyperuricemia resulting in gout have an overproduction of purines. Therefore, if the…

Gout is caused by excess uric acid in the joints as a result of accumulation or inefficient elimination. Uric acid is a byproduct of purines. While increased uric acid levels – hyperuricemia – in the blood is common in gout cases, it doesn’t mean that individuals with hyperuricemia will certainly develop gout. When kidneys fail to get rid of the uric acid, it ends up crystallizing and accumulating in the joints, resulting in inflammation. Fortunately, there are a number of natural remedies that…

In addition, gout is indicated by excessively high levels of uric acid, which is referred to as hyperuricemia in an individual. The primary cause of hyperuricemia is underexcretion of the kidneys (Buttaro, Trybulski, Bailey, & Sandberg-Cook, 2013). Although not the sole indicator, hyperuricemia is a good indication of gout disease. However, not all individuals who have hyperuricemia will develop gout. In order to diagnose gout disease, the urate levels in the serum must be 7 mg/dL for men and 6…