Gene expression

which is unique to the person, except for the case of twins. But, what makes the cells different, is that some of these cells have certain genes that are either turned on or turned off. The genes are encoded in the DNA, which is all the same, but the gene expression is different. This means that the genes in our red-blood cells are expressed differently than the genes expressed in our lung cell, for example. And that lung cell will always stay a lung cell, it…

we performed a comparative profiling of the proteins and lipids of wild type (WT) and Lcn2-deficient mice fed either standard chow or a methionine- and choline-deficient (MCD) diet. Label-free proteomics and 2D-DIGE protein expression profiling identified differential expression of BRIT1/MCPH1, FABP5, HMGB1, HBB2, and L-FABP, results confirmed by Western blotting.…

have. There is a DNA gene test that determines the sport a child will excel at (Niemi, 2005) to a point of achieving professional status (Guth, 2013). These testes may not determine the exact sport that they will play but whether or not they give a genetic advantage (i.e power, endurance, performance, etc.). Gabby Logan (Olympic gymnast) discusses in an article about an individual that can excel at running or swimming may they possess a certain kind of fast-twitch muscle fiber gene (Logan,…

to support cross-database queries and link the sample metadata towards corresponding experimental data in diverse archival databases. 4. BioSystems The NCBI BioSystems Database provides integrated access to biological systems and their component genes, proteins, and small molecules, as well as literature describing those biosystems and other related data throughout Entrez. This database acts as the centralized storage of data and also assists on database computation regarding biological systems…

2003). N. crassa comprises of two sPLA2 proteins encoded by NCU06650 and NCU09423 gene and their predicted primary structures possesses conserved residues similar to other microbial sPLA2 members of group XIV. The sPLA2 protein (186 amino acids) encoded by NCU06650 gene consists of a 19 amino acids long predicted N-terminal signal sequence and 4 Cys residues while NCU09423 (249 amino acids) encoded sPLA2 gene is comprised of a predicted signal sequence of 23 amino acids and 6 Cys residues…

components into surrounding tissue (121). Key players that help mediate necrosis include ROS, Calcium ions, poly-ADP-ribose-polymerase (PARP), and lysosomal proteases (888). PARP is an enzyme that is responsible for repairing DNA damage, such as strand breaks. Cells that have undergone a traumatic cellular insult typically have damaged DNA. PARP will deplete cellular ATP in an attempt to repair the massive damage to DNA. Several proteases are activated by increased cellular calcium ion…

site to obtain information. The first organization is Gene Testes. Gene test help support the appropriate use of genetic services used in patient care and helps to aid in personal decision making. Gene Tests provides lists…

Introduction: Lactase is an enzyme that helps to digest lactose, a sugar found in many dairy products (U.S National Library of Medicine 2013). This enzyme is made through instructions provided by the LCT gene. Lactase is primarily produced and found in the cells that line the walls of the small intestine. At the brush border, an area where microvilli absorb nutrients from food as it passes by, lactose breaks down lactose into simpler sugars like glucose through a hydrolysis reaction (Biology…

The gaseous hormone ethylene is perceived by the ethylene receptors which reside at the endoplasmic reticulum membranes4. In the genetic model plant Arabidopsis, there are five ethylene receptors (ETR1, ERS1, ETR2, ERS2, and EIN4), that fall into two subfamilies depending on functional kinase activity, and a subset of the receptors contains a receiver domain which promotes interaction with CTR15, 6. Interestingly, the receiver domain of ethylene receptors has a remarkable structural similarity…

This type of food is called genetically modified food. Genetically modified food comes from plants that have been altered in laboratories. This technology can be accomplished by moving genes from one organism to another by changing genes in an organism that are already present. These changes result in the expression of attributes not found in the original organism. The technology was developed so that food could have specific, desirable traits. Why are GM foods produced? Genetic engineering…