Gene expression

wide field of biochemistry includes exploration in the use of gene therapy for the treatment of cancers such as lung cancer. Though gene therapy is still in early stages of development, many researchers have concluded that gene therapy in therapeutic cancer treatment seems to be very effective and efficient. Gene therapy is the replacement of defective genes to enable the production of normally functioning genes. This replacement of genes is an adolescent and risky procedure and is often used as…

Final Exam Bacteria’s gene is only coding (makes a protein) meaning one gene equals one protein. Bacteria’s life history is a short lifespan, reproduces quickly in large number of individuals. Griffith finds that bacterial cells can be transformed. (Raven) There are two forms of bacteria, one that causes pneumonia and a nonvirulent that does not. The nonvirulent lacks enzymes to manufacture the coat of polysaccharide. Griffith performed a series of experiments with these types of bacteria on…

Differential alternative splicing human tissue network analysis of GUK1 Result Figure 4.12: Visualisation of alternative splicing gene GUK1 in human tissues. Differential alternative splicing genes between two different tissues comparison were shown on a different visualisation platform and tools in comparison with network analysis. (A) rMATS analysis. Histogram shows inclusion level ψ, per sample for each tissue comparisons. In this case, only exon 3 found as statistically alternative…

Cancer is the name given to the disease in which changes in gene expression cause an uncontrollable division of abnormal cells in any given part of the body. Cell growth and division are regulated by specific genes, and these genes include those for growth factors, along with their receptors, and the intracellular molecules of signaling pathways. Cancer can occur whenever a mutation alters any of these genes. These mutations can be random and spontaneous, however they can also be caused by…

patients and healthy controls has been depicted in Table ……., Figure ……... All the 15 CpG sites were more methylated in patients compared with control group. Methylation analysis of 15 CpG sites together revealed that the promoter region of Bcl11b gene in AS patients were hyper-methylated in comparison to healthy individuals…

Homeobox, also known as HOX genes, are genes that determine organ and limb formation during early embryonic development. Frances R. Goodman writes in his article “Limb Malformations and the Human HOX Genes” that humans have 39 HOX genes which are organized into four clusters. They have their own roles in the development of the central nervous system, axial skeleton, genitalia, and limbs. The study of HOX genes can lead to the identities of a number of human malformations. According to Shane C.…

difficulties in identifying and locating genes for gene scientists. Researchers have limited knowledge on the agriculturally significant genes such as increased plant hardiness, increased yield,or even environmental tolerance. Identifying a single gene involved with a trait is not enough for this step because researchers must understand how a gene could be regulated, what other effects it might have on the plant, and how it interacts epistatically with other genes in the regulation pathway.…

the processes of the cell cycle in both positive and negative ways. Tumor suppressor gene p53 is among the negative regulators of the cell cycle if affected by alteration, mutations or by interaction with oncogene products of DNA tumor viruses. All these mutations cause genetic changes in the cells and lead to cancer (Levine , Finlay, and Momand, 1991). TP53 plays an important role in tumor prevention, and gene stability and this have been demonstrated…

“I don’t know” I can still distinctly recall my eleven-year-old self repeatedly saying to anyone who tried to talk to me. It was my first day of school in America and that was the only sentence I could put together in English. I was born in China and lived there my whole life until my mother decided to move to New York. I thought I was just visiting her for winter break, but she dropped me off at school just a week after my arrival. As my new classmates tried to talk to me, I can see their…

the same way (21). Some studies showed an advantage in using anthracycline based chemotherapy in NEBC (22), whereas others didn’t show this benefit (2) (14). Some reports recommended the use of anthracycline based chemotherapy according to Ki-67 expression, usually if ki-67 is around 10%. For poorly differentiated carcinomas, especially the small cell subtype where ki-67 is more than 15% , cisplatin / etoposide is recommended as used in small cell pulmonary tumors (23) (24). Our case had a very…