Functional response

self-condensation of benzaldehyde with thiamine used as the base catalyst of the reaction. The next step was the preparation of benzil from the oxidation reaction of benzoin with nitric acid. In the oxidation reaction, the alcohol functional group of benzoin was oxidized to form the carbonyl functional group of benzil, while the nitric acid was reduced into a mixture of nitrogen oxides that formed toxic brown fumes. The final step was the preparation of tetracyclone from the aldol condensation…

In the Acid-Catalyzed Hydration of norbornene, water and sulfuric acid were added to the C=C double bond to form norborneol. Sulfuric acid acted as a catalyst, where it was not consumed in the reaction and helped to propel the reaction forward, as it was vital in forming hydronium ion and breaking the double bond. Both the products endo-norborneol and exo-norborneol were synthesized; however regioselectivity and stereoselectivity played a role as to which product was more preferred and whether…

OMEGA-3 FATTY ACIDS 1) Structure Figure 1.1 The omega-3 fatty acids are also known as ω-3 fatty acids or n-3 fatty acids which contain a long chain of polyunsaturated fatty acids and the chain ranges from 18 to 22 carbon atoms (Collins J.J., 2010). The fatty acids have two ends; the carboxylic acid end (-COOH) and the methyl end (-CH3). The carboxylic acid end is considered the starting of chain which is “alpha” and methyl chain is considered as the tail of the long chain…

INTRODUCTION Conformational isomerism is a type of stereoisomerism whereby the isomers are interconverted by rotations about the single bonds. There be terms used below such as eclipsed conformation, staggered conformation,dihedral angle and a few more. Eclipsed conformation is the conformation whereby the C-H bonds on one carbon is directly aligned with the C-H bonds of the adjacent carbon. When the C-H bond of one carbon bisects the H-C-H bond on the adjacent carbon, it is known as staggered…

Carbonyl compounds are the compounds the contain C=O group which is called carbonyl group (double bond oxygen to a carbon). There are many types of carbonyl compounds such as aldehydes, ketones, carboxylic acids, esters, amides etc. Aldehydes and ketones are the oxidation products of alcohols. Depending on the alcohol’s structure, the product obtained will be different. Primary alcohols have one carbon and two hydrogen atoms attached will produce aldehyde and then to carboxylic acid in two…

1-[Cyano(4-methoxyphenyl)methyl]cycloalkanol (VF-I) synthesized through the reaction of p-methoxyphenylacetonitrile and cyclohexanone using aq. NaOH and tetrabutylammonium hydrogen sulfate as PTC. NaBH4 and CoCl2 in 2:1 THF: H2O used for the reduction of VF-I to obtain 1-(2-amino-1-(4-methoxyphenyl)ethyl)cyclohexanol (VF-II). Further, venlafaxine derivative of the amino acid -carboxamide (VFCA-I toVII ) synthesized through coupling of N-Phthaloyl amino acid chloride derivative (2a-2g-…

devices. In addition, their novelty is rapidly growing in other fields where they are used as sensing elements in chemical sensors, electrocatalysts, liquid crystals, electrochromic display devices, information storage systems, semiconductors, functional polymers and molecular metals, among others. They have also found use in photodynamic therapy (PDT). [15-17] Synthesis of Phthalocyanines A number of different methods are available for the synthesis of phthalocyanines. Phthalonitriles are…

WHAT IS FORMALIN? Formalin is the trade name for an organic compound made by formaldehyde and water. It has the chemical formula CH2O and its chemical structure is as shown in figure.1. Uses: Formaldehyde is used mainly in the production of plastics (such as urea-formaldehyde plastics which is used in many manufacturing processes due to its useful properties such as flexural modulus, and a high heat distortion temperature, high surface hardness, low water absorption, high tensile strength, mold…

The goal of this lab was to conduct the reaction of 2-methyl-2-butanol with HCl to form 2-chloro-2-methylbutane, and to understand Sn1 and Sn2 reactions, in terms of how they are different and why one is more likely to happen over the other. The OH group in 2-methl-2-butanol is attached to a tertiary Carbon, meaning the reaction should occur via Sn1, a two-step reaction, and Cl should replace the OH group, to form a tertiary halide. HCl was added to 2-methyl-2-butanol and then several…

In the first step of the experiment, m-toluic acid reacted with thionyl chloride to form the acid chloride derivative of m-toluic acid. In this reaction, the carboxylic acid is first converted into an acyl chlorosulfite intermediate, replacing the –OH of the acid with a better leaving group. The acyl chlorosulfite then reacts with a nucleophilic chloride ion, at which point the chlorosulfite leaves in the form of sulfur dioxide and chloride ion. The remaining acid chloride then reacts with…