Extracellular

The human microbiome project The Human microbiome project was the first step into research about bacteria that is present in the human body, and the association with disease. The project was launched in 2007 and was set out to be a five year program. It was funded by the United States National Institute of Health (NIH) however it involved many specialist from many countries worldwide, the original funding was around $115 million. The main purpose of the project was to analyse “how changes in…

Paul Pierre Broca talked about ‘le grand lobe limbique’ in 1878 or the great limbic lobe and used the term “limbic” (from the Latin limbus for border) to the rounded rim of the cortex which also has the cingulate and the parahippocampalgyri. However, its supposed role in emotion was elaborated by the American physician, James Papez in 1937 in the influential paper titled ‘A proposed mechanism of emotion’. This anatomical model is called the Papez circuit.[2] In the year of 1948 scientist…

Jones. Mr. Jones appeared to be in distressed. He is now using his accessory muscles to breathe, crackles are heard on auscultation and there is decreased air entry in the left and right bases. Chest X ray revealed consolidation on the left lower lobe and atelectasis in the right lower lobe. After a series of investigation in the emergency department, Mr. Jones was commenced on Normal Saline at 125 mls/hr and he was given oxygen via non rebreather mask at 10L/min. He was then transferred…

Extracellular or bacterial cellulose (BC) synthesized by nonpathogenic aerobic bacteria in a culture medium containing carbon and nitrogen sources can be promising biodegradable nanofibers for composite materials because of their excellent mechanical properties [1]. Although BC is chemically identical to plant-based cellulose, it exists in extremely pure form and does not contain any hemicellulose, lignin, pectin or wax materials [2]. In addition, it has higher crystallinity, degree of…

INVIVO AND INVITRO STUDIES ON CHEMOPROTECTIVE EFFICACY OF RESVERATROL IN BREAST CANCER 1. INTRODUCTION 1.1 BREAST CANCER: Breast cancer is the most frequently diagnosed cancer and it is one of the leading causes of cancer death in women worldwide. Diet and Nutrition play a key role in carcinogenesis process, as reflected in the global differences in breast cancer incidence worldwide. High fat content, meat and low fiber diets were associated with high breast cancer incidence rates whereas…

Desmoplastic Ameloblastoma: A Case Report Abstract Ameloblastoma is the most common odontogenic tumor of epithelial tissue origin. There are various types of Ameloblastomas. In that, Desmoplastic ameloblastoma is one of the rare variant of ameloblastoma. Because of its rare occurrence, exact nature of the lesion yet to know. Hence nature of the Desmoplastic ameloblastoma need to be highlighted. We report a case of desmoplastic ameloblastoma in a 45-year-old female with a painless swelling in…

occurs in women since the breasts of a woman are mammary glands surrounded by fatty and fibrous connective tissue. Similar to other body parts, the female breasts contain a vast network of vessels known as the lymphatics which drain any remaining extracellular fluid found in body tissue. Since there is vein like vesicles present in the female breast, the lymphatic system serves as the primary mechanism of defenses in the immune system. Unlike genetic disorders, cancer cells are pleomorphic…

Abstract Angiogenesis is an essential process for organ growth and repair. Thus, an imbalance in this process can lead to several diseases including malignancy. Angiogenesis is a critical step in vascular remodeling, tissue damage and wound healing besides being required for invasive tumor growth and metastasis. Because angiogenesis sets an important point in the control of tumor progression, its inhibition is considered a valuable therapeutic approach for tumor treatment. Chronic liver disease…

There are certain animals, plants, fungi, bacteria, and viruses that tolerate and actually thrive in extreme conditions. These organisms are called extremophiles. The word extremophile breaks up into “extreme” and the suffix “phile” literally means “one who loves.” These organisms flourish in the uninhabitable places that vary from extremely high and low temperatures, high pressures, high salinity, the absence of water, and extreme amounts of radiation just to name a few. Many of these…

In a human body, there are four core classifications of tissues, which are epithelial tissue (plural form epithelium), connective tissue, nervous tissue, and muscle tissue. And each of these tissues has its own unique function in our body that makes us a perfect complement function organism. In the beginning, the simplest structural elements or atoms such as calcium (Ca +2) or sodium (Na +1) involve in the basic unit of living matter. These matters combine to form other matters like the fusion…