are achieved via inhibition of the synthesis of prostaglandins involved in fever, pain, swelling and inflammation. ETD is administered as a racemate. As with other NSAIDs, the S-form has been shown to be active while the R-form is inactive. Both enantiomers are stable and there is no evidence of R- to S- conversion in-vivo. 3.1.5 Pharmacokinetics…
What four elements make up 96% of all living matter? _________________________________________ Concept 2.2 An element’s properties depend on the structure of its atoms 2. Below is a model of an atom of helium, correctly label the electrons, protons, neutrons, and atomic nucleus. 3. What is the atomic number of helium? _________ Its atomic mass? ________ 4. Consider this entry in the periodic table for carbon. What is the atomic mass? ______ atomic number? _______ How many…
Introduction Debates concerning the health effects of artificial sweeteners are relevant not only for scientists and dieticians, but also for diabetics and individuals who are trying to lose weight. According to the American Diabetes Association (2014), aspartame (Equal, NutraSweet); acesulfame potassium (Sunett, Sweet One); neotame; sucralose (Splenda); saccharin (Sweet ‘N Low, Sweet Twin, Sugar Twin); and advantame are six alternatives to natural sugar that are commonly added to foods and…
In the Acid-Catalyzed Hydration of norbornene, water and sulfuric acid were added to the C=C double bond to form norborneol. Sulfuric acid acted as a catalyst, where it was not consumed in the reaction and helped to propel the reaction forward, as it was vital in forming hydronium ion and breaking the double bond. Both the products endo-norborneol and exo-norborneol were synthesized; however regioselectivity and stereoselectivity played a role as to which product was more preferred and whether…
These two compounds have the same connectivity although they are not identical, therefore they are stereoisomers. Since they are not enantiomers, so they have to be diastereomers. Like itself, substituted cyclohexane, methyl cyclohexane additionally experience the chair interconversion. As the figure above shows, axial methyl cyclohexane and equatorial methyl cyclohexane are interconverted…
Introduction: Enzymes play a major role in biological systems to catalyze and control different reactions. The study of enzymes’ behaviors toward substrates and products is significant to understand various enzyme catalyzed reactions in living organisms. One of the most important enzymatic group is cytochrome P450 (CYP450) which contribute to the metabolism of many endogenous as well as exogenous substances such as drugs. Although there are several subtypes of CYP450 family, CYP450 1A1 is going…