the current study, the effect of nilotinib, a marketed drug used by human beings that has a well-defined safety profile, was investigated on APAP-induced hepatotoxicity in mice. Nilotinib treatments for mice were found to protect against APAP-induced liver injury as indicated by decreasing the elevated levels of serum ALT, AST, LDH and GGT activities. The protective effect exerted by nilotinib against APAP-induced liver injury was further confirmed histopathologically by preventing APAP-induced…
The world of microbiology is a vast one. In theory, microbiology is the study of single celled micro organisms and viruses, that work independently of each other. These microbial cells are the backbone and fundamental unit of life. Most of the biomass present on earth today is microbial, with almost 5.3x10^30 cells present, mostly in terrestrial and oceanic subsurfaces. Within these subsurfaces, many microbial communities exist, with especially specific types of bacteria having important niches…
After the cell reaches the confluence, the various concentrations of the samples were added and incubated for 24 hours. After incubation, the sample was removed from the well and washed with phosphate-buffered saline (pH 7.4) or MEM without serum. 100µl/well (5mg/ml)…
expect the brain to be as small as it was. The sheep brain dissection lab was done in order to help students understand how important the structures and functions are in the human brain. A few external details I was able to identify were the frontal, occipital, temporal and parietal lobes as well as the difference between gyri and sulci. Some internal structures I struggled to point out was the hippocampus and the pineal gland, in the future, I would do a further analysis of the clear…
Enhancing Society at a Cost In recent years, scientists developed genetic engineering in animals. Gene modification enhances animals by increasing fertility, and allows the possibility of cloning. However, cloning and designing animals leads to the application of genetic modification in humans. In Dinesh D’Souza’s essay, “Staying Human,” he reveals the positive and negative effects of genetic engineering, but he affirms the unethical application of genetic engineering. Because of this…
incision along the midline of a frog's body from pectoral gland to the pelvis. The entire cavity, filled with organs, showed up. I was amazed to see internal organs with my naked eyes. The next dissections were a cow eyeball, to observe its anatomical structures, and an earthworm to learn about its circulatory system. Even in elementary school at annual Talent Show, I spoke about the solar system and displayed a model with rotating planets. My passion and past experiences made me pass entrance…
where its structure dictates its function in storing the genetic information of the organism (Rafael, 2010). This molecule contains genes which encode proteins needed for the complex biochemical metabolic reactions which occur within the organism (Rafael, 2010). The DNA molecule consists of 2 complementary strands in a helical structure where each strand serves as an informational template for the offspring during duplication (Rafael, 2010). An organism is made up of a vast collection of cells…
B D E C O S Y S T E M 2 0 1 5 Petersohn, D. ; Spencer, M. ; Fratila, A. ; Chi-RenShyu Present a novel method by using an in-memory computing environment database for all mammals in Ensembl release 80 for identifying, extracting, and indexing palindromes in a searchable. [27] Rathore, M.Mazhar ; Ahmad, Awais ; Paul, Anand ; Daniel, Alfred Proposes a set of requirements for obtaining pervasive, integrated information system of EOS and associated services like real-time and offline data…
Genetic testing is a medical test that examines DNA, identifying any changes in it. The results obtained can determine if a person has or can pass on a genetic disorder or confirm any suspected genetic condition. However, a positive result doesn’t guarantee you would develop a disease even if you are a healthy individual. In return, a negative result doesn’t guarantee you possess a specific disorder. There are different types of genetic testing like diagnostic testing and prenatal testing just…
The Children of Men by P.D. James is a dystopian novel that takes place in a world where humans are no longer able to conceive children. Since the year 1995 all humans have become infertile and although they are required to receive tests to figure out why this has occurred there is no official cause to the epidemic. The protagonist of the novel, Theodore “Theo” Faron, is an academic who specializes in History, and teaches at the undergraduate level and he used to work for the government. Since…