elevation of blood pressure may easily cause the rupture of the tiny arteries inside the brain. - Tumor: Angiomas and metastatic are both highly vascularized tumors which are able to bleed into the brain tissue - Problems with the arterial wall: e.g Amyloid angiopathy (a degenerative disease of arteries) or Aneurysm (weakening of arterial walls) - Drug usage (Zuccarello, 2013) Acute presentation & diagnosis: Prognosis: Intracerebral haemorrhage has a high rate of morbidity and mortality as…
1. Neurogenesis and memory 1.1. Neurogenesis in the hippocampus The hippocampus is a brain region that responsible for learning, memory and mood. One of the important reasons for memory and mood dysfunction is the dentate gyrus (DG) reduction [12, 13]. The subventricular zone (SVZ) and the subgranular zone (SGZ) of neural progenitor cells generated neurons and glia in adulthood and during adulthood [14]. Neurogenesis also have a role in mood regulation; the dorsal hippocampus is an…
A concussion, a type of traumatic brain injury, causes malfunctions in ones brain. The major causes of the malfunctions are due to the damage of neural functions. The damage of neural function can lead to vision disturbance, instability, and slow cognitive recognition. There are other symptoms that are associated with concussions that have not been listed. A person can be suffering from a concussion with out their knowledge. Concussions affects a person’s function rather than the structure of…
My journey starts in Rwanda, a small country in East Africa. It started after I excelled in the national examination, an exam for high school students pursuing college admission, and got rewarded a scholarship to study college in the US. The experience I gained throughout my scholarship period, research, and background inspired me to pursue graduate studies. This goal has been an important reason for both my education and life pathways. In Rwanda, my country of birth, there is a presidential…
Alzheimer’s disease is a progressive condition that occurs in the brain, begging in the hippocampus and continuing damage to the cerebrum, which effects the memory, thought and behavior of an induvial. Alzheimer’s is a form of dementia. Dementia is not a specific disease, rather a general condition that describes an impairment of normal mental functions, such as that of memory loss that impedes normal day to day life. Approximately 60-80% of individuals experiencing dementia are victims of…
there are twenty three states and the District of Columbia that have made medicinal cannabis legal. Cannabis has a plethora of medicinal uses. In a two thousand and six study, they had come to find that tetrahydrocannabinol slows the forming of amyloid plaques by blocking the enzyme in the brain that makes them, all in all slowing down Alzheimer’s. Another study was conducted on cannabis and Dravet’s syndrome. In this study a young little girl named Charlotte Figi was suffering from Dravet’s…
Diagnosis Diagnosis of PD is based predominantly on the detailed assessment of signs and symptoms and medical history. The clinical diagnosis of PD is made when two or more of the cardinal symptoms are asymmetrically present. Again the cardinal symptoms include bradykinesia, resting tremor, rigidity, and postural instability with all other causes ruled out. Unfortunately, no lab test, radiologic study, or biopsy can confirm the diagnosis of PD. Therefore, the progressive decline of motor…
IV. Chronic traumatic encephalopathy Another major facet of sports-related concussions is Chronic Traumatic Encephalopathy (CTE) as it’s considered to be a gradual neurodegeneration due to repeated mTBI (Gavett et al., 2011). Since there are many high-contact sports (such as football, hockey, boxing, etc.) as well as high chances of accidental injury in non-contact sports – repeated head injuries are very common (Gavett et al., 2011). This is another reason sports-related concussions…
"I now have absolute proof that smoking even one marijuana cigarette is equal in brain damage to being on Bikini Island during an H-bomb blast.” -- Ronald Reagan. There has been so many different types of research on this specific plant about the positive and negative possibilities it can have on our world. Many people argue about how it can benefit for medical studies. Marijuana. Weed. Pot. Whatever you want to name it, it 's one of the most popular illegal substances in the world,…
Ubiquitin-conjugating partners of CHIP: In section 3, after " fate of substrates": E2’s are the family of enzymes, having highly conserved ubiquitin conjugating domains. These enzymes, in combination with E3s, play an important role in determining the fate of substrate proteins by selecting a lysine residue on which ubiquitin moiety must be added. In section 3, after Murata, et al. 2003: An in vitro study has shown that CHIP, with the aid of UbcH5 and UbcH6, two other E2s, can efficiently…