Adrenal insufficiency

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medicine for the paycheck, prestige, or simply to carry on the family business, my desire for pursuing a career in medicine has been driven by another motive entirely. The odds were one out of 15,000 and I was chosen — I was diagnosed with Congenital Adrenal Hyperplasia (CAH) at the age of eight. CAH is a genetic disorder that affects the general health, growth, and development of the body. Not only does this condition involve the taking of daily medication for the rest of my life, I am also…

Non-classical congenital adrenal hyperplasia or NCAH is a disorder that affects both men and women from late childhood through the rest of their lives. Compared to its sister form, classical congenital adrenal hyperplasia, it is non-life threatening. The Mayo Clinic, a service that gives people medical information and helps set up doctor appointments, defines NCAH as “a collection of genetic conditions that limit your adrenal glands' ability to make certain vital hormones.” These vital hormones…

eventually help in treatment of cases and counseling of families. Keywords: Growth; Precocious Puberty; Congenital Adrenal Hyperplasia; Cyp21; Gonadotrophin Releasing hormone List of Abbreviations: 17 OHP: 17 hydroxy progesterone; ACTH: adrenocorticotrophic hormone; BMI: Body mass index; Bp: Base pair; CAH: Congenital adrenal hyperplasia; CT: Computeized tomography; cyp21: congenital adrenal hyperplasia results from steroid…

Adrenal insufficiency so called Addison Disease is an endocrine condition defined as the inadequate production or action of glucocorticoids, principally a steroid hormone called cortisol. The adrenal insufficiency is a rare condition in childhood, but it carries the risk of adrenal crisis in the event of a child becoming unwell as a result of intercurrent illness, injury or surgery. Pathophysiology The adrenal glands have many functions contributing to homeostasis in the body. This is one of the…

The Effects of Overtraining on the Adrenal Gland, With a Focus on Cortisol and Adrenal Medullary Response As a society, we generally view exercise such as running, swimming, boxing, or other forms of aerobic training, as positive acts towards maintaining our health and stress levels. Even so, two things that are often not acknowledged when considering exercise are moderation and recovery. Paired with aerobic exercise, the absence of adequate moderation and recovery can result in overtraining.…

Primary adrenal insufficiency (also known under the eponym Addison’s disease) occurs when the adrenal glands situated on top of the kidneys produce inadequate amounts of glucocorticoid and mineralocorticoid hormones. Autoimmune destruction of the aforementioned glands is the most common cause of primary adrenal insufficiency in the developed countries, whereas tuberculosis is the second most frequent cause worldwide. A plethora of autoimmune comorbidities can be associated with primary adrenal…

Addison’s disease is also known as Primary adrenal insufficiency. It is a long-term endocrine disorder happens in the adrenal glands. There are two adrenal glands, they are located on the top of each kidney. The adrenal gland has 2 part: the inner part is the medulla, the outer part is the cortex. The medulla secrets the catecholamines and cortex secret aldosteron, cortisol and androgen. Aldosteron regulate the potassium and sodium level by increasing sodium and water reabsorption in the…

About one in every 100,000 people are affected by a rare endocrine disorder called Addison’s disease. It occurs in all groups and affects both sexes. In fact, Addison’s disease is often called chronic adrenal insufficiency, or hypocortisolism (Robinson, 2015). Our body produces cortisol by the adrenal glands, which are located just above the kidneys. As part of the endocrine system, the glands produce hormones that give instructions to every organ and tissue in the body. It is an important job…

Case Study: Clinical Biochemistry investigation into Addison Disease Introduction A fifteen year old male presented to the Emergency Department (ED) with his mother in St. Vincent’s University Hospital (SVUH) on the 8th September 2017 with suspected Addison disease (AD). On initial examination he was found to have severe abdominal pain and prolonged vomiting. Other symptoms could include fatigue, myalgia, weight loss and salt craving (Brooke & Monson, 2017). Laboratory Investigation and Results…