Adrenal insufficiency

One of the other types of stress is Episodic Acute Stress. When acute stress starts to happen, more often it is called episodic acute stress. People who always seem to have a continuous crisis in their life seem to have episodic acute stress. People that tend suffer from this always seem to be in a rush, they take too much on and tend not to be able to organize themselves to deal with demands and pressures. People who have Episodic Acute stress are often short-tempered, irritable, and anxious.…

The hormone cortisol is a very important hormone for regular function in humans and many other animals. Cortisol is a steroid hormone (a derivative of cholesterol).1 It is produced in the adrenal glands of the kidneys2 and is especially important when an individual faces a stressor.3 Unusually high or low concentrations of cortisol will almost certainly have an adverse effect on regular human function. In healthy humans, cortisol is at its highest concentration when an individual…

Cushing’s Disease Description Cushing’s Disease is an adrenal gland disease in which there is an excess of the steroid hormone, cortisol, within the body. With Cushing’s Disease the body releases too, much of the adrenocorticotropic hormone (ACTH). This disease is rare as it effects 10 to 15 people per million each year. Women and men both can be diagnosed with this disease, but women tend to be affected more than men. The disease can be fatal is not treated correctly and promptly. Etiology…

The Role of Alpha-1 Adrenergic Receptor in Disease Adrenergic receptors are a class of G-protein coupled receptors (GPCRs) which are activated by catecholamines in the central and peripheral nervous systems. Alpha-1 adrenergic receptors (1-AR) are systematic vasoconstrictors: their activation constricts blood vessels by the contraction of vascular smooth muscle. These transmembrane receptors are activated by the binding of epinephrine or norepinephrine, which creates intracellular signals via…

synthesized by the anterior pituitary gland and its release is stimulated by the corticotrophin-releasing hormone (CRH) which stimulates the release of corticosteroids (e.g. cortisol) from the adrenal glands. ACTH plays a major role as response to any biological stress in the hypothalamic-pituitary-adrenal axis…

skin' (Nieman and Chanco Turner, 2006). Although the adrenal glands are part of the endocrine system, they also works alongside the nervous system to protect the body. A physiological change that Addison's disease can have on the nervous system is orthostatic hypotension…

You can feel a rush of energy go through your body. Your hands start to shake, you are alert, the energy you have is through the roof. It’s called adrenaline. The hormone secreted by the adrenal glands, especially in conditions of stress, that gives you that extreme rush of energy that makes you feel like you can do almost anything. Most of the cases, when you get an adrenaline rush, are in fight or flight situations. The fight-or-flight response is a physiological reaction that occurs in…

The Controversy behind Endocrine Disruptors Endocrine disruptors are chemicals that can cause an individual’s endocrine, neurological or immune system to not function properly. Many chemicals have been deemed endocrine disruptors but are still used heavily today. They can be seen in things such as, plastics, cosmetics and pesticides among other products. Whether or not the benefits that using certain compounds affords us is worth the damage they can potentially cause is the basis for the…

Glucocorticoids are steroid hormones which are produced predominantly in response to stress in the adrenal gland (Davis & Sandman 2010; Korgun et al. 2012). The physiological effects of glucocorticoids occur when the hormone are bind to, and mediated by the glucocorticoid receptor (Erhuma 2012). It plays a wide range of vital physiological roles that are necessary for healthy implantation and pregnancy processes (Korgun et al. 2012). As glucocorticoids are critical in the regulation of the…

I froze in horror as I read the Facebook message that was sent to me. He’s gone. My heart fell to my gut. I felt a sharp pain down my spine. My head started throbbing- I wanted to throw up. My body trembled, and my hands turned to ice. I started looking around the room to make sure I wasn’t dreaming. I was trying to wake myself up from a nightmare that was my reality. According to Sapolsky, a neuroscientist of great renown, a “Stressor” is an event in the outside world that knocks you out of…