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268 Cards in this Set

  • Front
  • Back
Greater than or equal to 10% above ideal body weight is considered
Overweight
Greater than or equal to 20% above ideal body weight is considered?
Obese
Greater than or equal to 100% of ideal body weight is considered?
Morbid obese
BMI of 20-25 is
Normal
BMI above 27.5 is
Mild obese
BMI of 30-40 is considered
moderate obese
BMI above 40 is considered
Morbid obese
Men have and ideal __% or less of body fat t
15%
Women have an ideal __% or les of body fat
22%
Treat your ___, not the ___
patient; numbers
Studies with adoptees showed that they are more likely to develop weight like their ____ parents than their _____ parents
Biological; adoptive
Adipocytes are most easily added during the ___ trimester of pregnancy for the fetus; the first ___ years post deliver; and during ___
third trimester; 1-2 years; puberty
Adipocytes can be ___, but never ___
added; lost
__ _____ theory, the body will tend to return to a certain point; weight loss for more than 2 years will lower this point
Set point theory
Some believe that people who are morbidly obese have a lesion in the __ __ ___ of the ______
ventro medial nucleus; hypothalamus
When people who tend to be slender eat a high-fat meal, their LPL levels ____
Decrease
When people who tend to be heavy eat a high-fat meal, their LPL levels ____
increase
These are found on vascular walls and they remove fat from the blood and deposit it in adipose cells
Lipoprotein lipase (LPL)
Higher levels of LPL, ____ craving for __
Increase; fat
Ground beef is __% fat
64
Extra lean ground beef is about __% fat
47%
On a calorie restricted diet there should be:
__% carbs
__% protein
__% fat
55% carbs
15-20% protein
20-30% fat
On a calorie restricted diet:
Women: ___calories
Men: ___ calories
Women= 1000-1200
Men= 1200-1500
__% of patient lose 10lbs or more; only about _% keep it off for 5 years
25%; 2%
___ in a low-carb, high-protein diet cause a suppression in appetite
Ketosis
____ ___ diet usually provides 300-500cals/day; patient drinks 1-1.5L of water/day; damage to kidneys and other organs
Liquid protein
Novelty diets are bad because (3 things):
Insufficient micronutrients
Most don't work very well
most are difficult to stay on for very long
People who ate 17meals/day had __% lower cholesterol, __% lower cortisol, __% lower insulin in the blood
15; 17; 28
**also decrease LPL, sympathetic stimulation and proliferation of arterial smooth muscle cells
Calories in one pound of:
Raw veggies= ?
Cooked veggies= ?
Fresh fruit= ?
Pizza= ?
100
200
300
1008
Exercised can increase metabolism for up to __ hours?
72
Dr. Michael Colgan thinks workouts should be __-intensity, __-repetititon exercise
low-intensity; high-repetition
What supplements does Dr. Colgan recommend?
Omega 3 fats
L-carnitine
Chromium
TOPS stands for?
taking pounds off sensibly
Approximately ___ new chemicals are introduced each year
1000
Over ____ xenobiotics are in current use
100,000 (foreign to our bodies)
In 1989 _______ pounds of chemicals were released into our water and atmosphere
5,705,670,380
There are about ____ serious pesticide poisoning every year
3,000,000
From what do endotoxins form?
normal metabolism (lactic acid, urea, oxidants)
Pathogenic bacteria
Detoxification process itself can produce ___ intermediate metabolites and __ ___
toxic; free radicals
The liver congest ___, __ soluble toxins intto ____, ____ soluble compounds
non-polar, lipid soluble; polar, water soluble
Oxidative phase; use of cytochrome P450 enzyme system aids in oxidizing, reducing, or hydrolyzing the toxin into intermediates
Phase 1 (creates intermediate compounds and free radicals)
T/F: some intermediate compounds are more toxic than the original toxin
True
Conjugation phase; toxin is made into less toxic, water-soluble substance which can then be safely excreted
Phase II
Benezene is converted to phenol by what phase?
Phase 1
Phenol is converted to phenyl sulfate by what phase?
Phase 2
Liver enzymes indicate what?
pathological damage to hepatocytes (SGOT, SGPT)
Liver biopsy determines?
type of pathology
Phase 1 is measured by ___ clearance. What do we measure it in?
Caffeine; measured in syliva
Caffiene (No-Doz) is cleared primarily by phase __
phase 1
Phase 2 measures the clearance of ____ and ____. What do we measure it in?
aspirin and tylenol; measured in urine
Low Phase __ leads to build-up of toxin in the tissues
1; need to provide nutrients that support the C-P450 system
___ activates the cytocrhome P450 enzyme system
protein
Fasting may ___ ____ ____ into the blood
release more toxins
A high refined carb intake may ___ the effectiveness of the C-P450 system
decrease
____ fats and healthy ____ help maintain the C-P450 systems
monounsaturated; polyunsaturated
___ are needed to quench the free radicals produced by phase 1 of detox
antioxidants
What are two Vitamins and one mineral that are important for the C-P450 sytesm
Vit C and E; selenium
___ provides one of the phase II pathways; serves as an antioxidant
Glutathione
___ helps repair and preserve the integrity of gut muscles
Glutamine
Def in these inhibit the C-P450 sytesm
Zinc, copper, magnesium and molybdenum
___ & ___ provide sulfer for phase II conjugation
Methionine and Cysteine
___ stimulates the growth of bifidus
Fructooligosaccharides
__ absorbs toxins and helps clean the intestinal walls
Fiber
___% of all detoxification takes place in the gut
15-20%
Phase I support is from?
Protein
antioxidants
eliminate refined carbs
mono- and polyunsaturated fats
zinc, copper, magnesium, molybdenum
Phase 2 support is from?
Glycine, glutamine, cysteine, glutathione, antioxidants
Silymarin (Milk thistle)
In infants, cows milk decreases the bioavailability of __
iron ~anemia
Evidence suggest that a combination of genetic predisposition and consumption of cows milk can lead to ______
Type 1 juvenile onset diabetes
All diabetic children had antibodies to ____ in their blood
cow's milk protein (Bovine Serum albumin (ABBOS)
__ antibodies to cows milk are independently associated with increased risk of IDDM
IgA
___% of monozygotic twins will not get the disease, leading to ____ risk factors
50-70%; non-genetic risk factors
___ may independently initiate the auttoimmune process by causing the initial damage of the ___-cell
Nitrosamines; beta-cell
Diabeticis have a ______ molecular marker
HLA-DQB1
____ is strongly endorsed as the primary source of nutrition during the first year of lilfe for all infants
breast-feeding
___ has been associated with a high incidence of cataract
lactose
Consumption of ___ and ___ were constantly positively correlated with pancreatic cancer mortality rates in males
milk and cheese
___ and ___ may be linked to an individuals inability to propery break down a protein found in milk
autism and schizophrenia
When not broken down, the milk protein produces ___ that are taken up by areas of the brain which lead to dysfunction
exorphins
When children with autism were put on a milk-free diet, at least __% no longer had symptoms of autism or schizophrenia
80%
___-_____-_ was taken up by areas of the brain responsible for vision, hearing and communication in autism
Beta-casomorphin-7; this gives us proof that milk proteins are getting into the areas of the brain
The more ___-_ is in a man's blood the higher his prostate cancer risk
IGF-1
IGF-1 is linked to ___ ___ and __ ___
prostate cancer in men; and breast cancer in women
Cow milk contains __-____ ____-___ growth facts that identical to human IGF-1
pre-formed insulin-like
Milk has __ mg of calcium/ calorie
1.8
Spinach has __ mg of calcium/ calorie
3.5
How much protein does human milk have? How much does cow milk have?
Human= 1.1
Cow= 3.3
How much casein does human milk have? How much does cow milk have?
Human= 40%
Cow= 82%
How much whey does human milk have? How much does cow milk have?
Human= 60%
Cow= 18%
How much calcium does human milk have? How much does cows milk have?
Human= 340
Cow= 1250
How much phosphorus does human milk have? how much does cow milk have?
Human=140
cow= 960
Human milk is more ____ pH
Alkaline
Cows milk is more ___pH
Acidic
___% of asthmatics were cured by eliminating dairy products
50-70%
___ ____ destroys plasmalogen? What is it's source?
Xanthine oxidase; Bovine Milk Xanthine Oxidase
T/F Increased consumption of homogenized milk results in an increase of BMXO antibodies
True (Bovine milk xanthine oxidase)
Frank Oski found ____ in children who drank cows milk as infants
diseased arteries
1977 US senate select committee on nutrition did what?
Recommended that efforts be made to reduce the intake of milk and other dairy products
__ death rate for babies on human milk. ___ death rate for babies on cow's milk
human= 1.5/1000
Cows milk= 84.7/1000
For non-breast-fed infants, deaths from BI infections were __x's higher than in breast-fed infants
40x's
How much phosphorus does human milk have? how much does cow milk have?
Human=140
cow= 960
Human milk is more ____ pH
Alkaline
Cows milk is more ___pH
Acidic
___% of asthmatics were cured by eliminating dairy products
50-70%
___ ____ destroys plasmalogen? What is it's source?
Xanthine oxidase; Bovine Milk Xanthine Oxidase
T/F Increased consumption of homogenized milk results in an increase of BMXO antibodies
True (Bovine milk xanthine oxidase)
Frank Oski found ____ in children who drank cows milk as infants
diseased arteries
1977 US senate select committee on nutrition did what?
Recommended that efforts be made to reduce the intake of milk and other dairy products
__ death rate for babies on human milk. ___ death rate for babies on cow's milk
human= 1.5/1000
Cows milk= 84.7/1000
For non-breast-fed infants, deaths from BI infections were __x's higher than in breast-fed infants
40x's
pH stands for ___, what is it measured by
potential of hydrogen; logarithmic scale
The blood, CSF, interstitial fluid, intracellular fluid and lymph should be acidic or alkaline?
alkaline
What should be acidic in the body?
stomach
How long does it take our kidneys to buffer blood pH/
Hours to days
How long does it take our lungs to buffer pH
Minutes
How long does it take the buffer systems to work?
seconds
A ___ is something that restores the original pH of a solution when an acid or base is added
buffer
pK= what?
ionization constant...its is the point of equilibrium
What is the pK of bicarbonate? where does it operate?
pK= 6.1
operates outside the cell
Bicarbonate requires __ and ____
sodium and alkalizing minerals
Bicarbonate system is very ___. Blood can handle 300 times more acid than water
powerful (first gear)
Phosphate buffer's pK is? Where does it work?
pK= 6.8
primarily inside the cell
The phosphate buffer uses ___
potassium
The protein buffers' pK is?
pK=7.4; many AA's can accept or reject H ions
__ is the mineral content of food that survives after we burn it
Ash
Animal flesh, eggs, dairy products and most cereal grains leave an __ ash
acid
All vegetables and most fruit leave a __ ash. What are the exceptions?
alkaline; exceptions= plums prunes and cranberries
What is the alkaline/acid test?
eat only acid ash foods for two days, then check pH of the first urine of the third day
In the alkaline/acid test we check the __ urine of the __ day
1st urine of the 3rd day
In the alkaline/acid test= if there is an acidic urine what is the result?
Adequate mineral reserves
In the alkaline/acid test= if we have an alkaline urine what is the result?
Low mineral reserves
As your patient progresses they should need __ doses of ___ supplements
smaller doses of fewer supplements
Ice makes it better if its ____
physical
Heat makes it better if its ____
emotional
When we eat too much protein the kidney will dump ___ in to the urine
Ammonia...making the urine more alkaline.
**when the patient is actually acidic
___ stimulate the sympathetic NS and motor neurons
Nociception
___ makes anaerobic metabolism and lactic acid build up
Hypoxia (from muscle spasm...in nociception)
___ leads to decreased ATP & protein synthesis, cortisol release, cell damage, chronic inflammation, swelling of mitochondria
Nociception
pH as low as __ is
5.4
__ lowers nociceptor threshold and activates bradykinin
Tissue acidity
__ promotes inflammation, pain vascular permeability, fibrotic deposition, disc degeneration, leukocytes
Bradykinin
__ are involved in acute/chronic inflammation, atherosclerosis, auto-immune disorders, neoplastic disease, bone loss
cytokines
An alkaline diet, omega 3 FA, antioxidants, bioflavonoids, proteolytic enzymes can reduce ___ and ____
Bradykinin and cytokines
___ deficiency decreases aerobic glycolysis
magnesium
__ deficiency increased free radical production
Magnesium
___ deficiency increased platelet aggregation, osteoporosis, and cardiac arrhytmia
Magnesium
____ ___ increases osteoclasts, release of collagenase, release of lysosomal enzymes, vascular permeability, inflammation
Arachidonic acid
___ are slow to react with oxygen and other chemicals
Saturated fats
___ fats are generally solid at room temperature, stick together and deposit w/in cells, organ and arteries
Saturated fats
Saturated fats __ carbons and longer are used primarily for energy
14
Saturated fats __ carbons or less are liquid at body temperature such as coconut oil and butryic acid in dairy
10
___ fats are usually liquid at room temperature
Unsaturated fats
Unsaturated fats have a __ configuration; with a __ charge
cis configuration; negative charge
Omega 3 are from what acid?
1)Alpha-linolenic
2)Linolenic
3) arachidonic acid
4)oleic acid
Alpha-linolenic acid
Flaxseed oil, GLF, Hemp seed and pumpkin seed are examples of _____ acid
Alpha-linolenic acid
Cold water fish, algae, egg yolk are sources of __ and ___
EPA and DHA (omega 3)
Omega 6 is NOT made from:
1)linoleic acid
2) gamma linolenic acid
3) Arachidonic acid
4) alpha-linolenic acid
Alpha-linolenic acid
Corn oil, safflower oil, sunflower oil, soybean and walnut are sources of ___ acid
Linoleic acid
Evening primrose oild, borage seed oil, black currant seed oil, mom's milk are sources of ____
Gamma linolenic acid
Animal products, peanut oil are sources of ____
Arachidonic acid
Omega 9 is made from ___ acid
Oleic acid
Olive oil, rapeseed oil, oil of almond, cashew macadamia pecan and peanut are sources of ___ acid
oleic
What can block delta-6-desaturase?
high cholesterol, sat fats, trans-fat, stress, alcohol, sugar, atopy, infancy, aging, steriods, etc
2% milk has __% of fat
30%
If there are no double bonds it is a ____ fat
Saturated
If there is one double bond is it a ____ fat
monounsatruated fat
2% milk has __% of fat
30%
If there are more than 2 double bonds it is a ___ fat
Polyunsaturated fat
If there are no double bonds it is a ____ fat
Saturated
__ degrees is the melting point for saturated fats
149
How many essential fatty acids are there?
2
If there is one double bond is it a ____ fat
monounsatruated fat
What enzyme needs to be function in order for Omega 6 and Omega 3 to work?
Delta-6-desaturase
If there are more than 2 double bonds it is a ___ fat
Polyunsaturated fat
Odd number eicosinoids are pro- or anti-inflammatory
Anti-inflammatory
__ degrees is the melting point for saturated fats
149
Even number eicosinoidis are pro- or anti-inflammatory?
Pro-inflammatory
How many essential fatty acids are there?
2
What enzyme needs to be function in order for Omega 6 and Omega 3 to work?
Delta-6-desaturase
Omega _ can produce both anti- and pro-inflammatory eicosinoids
6
Odd number eicosinoids are pro- or anti-inflammatory
Anti-inflammatory
Even number eicosinoidis are pro- or anti-inflammatory?
Pro-inflammatory
Omega _ can produce both anti- and pro-inflammatory eicosinoids
6
Omega _ can only produce anti-inflammatory eicosinoids
3
Flaxseed has __% of alpha-linolenic acid (omega 3)
60%
GLV have __% of alpha-linolenic acid (omega 3)
50%
______ acid is the precursor to all omega 3 FAs
Alpha-linolenic acid
Magnesium, zinc, Vit B3,6 and Vit C are needed to convert ___ to series 1 eicosanoids
GLA (Gamma linoleic acid)
_% is the minimum EFA we need in our diet
2%
What is the optimal EFA % needed for men and women
5-10%
What can increased thirst or frequent urination cause (2 things)
Deficiency in EFA (essential FA) or DM
__,___ and __ damage EFA's
Heat, light and oxygen
EFA's are _____ fats
Polyunsaturated fats
Should you cook in corn oil, vegetable oil, sunflower oil?
NO
What % of our intake come from hydrogenated vegetable oil?
95%
Sears states that __% of our diet should be from fat
30%
97% fat free ham has __% of total fat
30%
DHA is very important in infants for the ___
CNS
T/F DHA should be given to autism pattients
FALSE, it exacerbates the symptoms
Studies using unaltered coconut oil ___ LDL and _____ HDL
Decreases; increases
Primary fatty acid in coconut oil is ______
Lauric acid-monolaurin
What is the largest cause of leaky gut?
inflammation
What are the consequences of leaky gut?
antibodies (RA, MS, SLE)
What is solid at room temp and slow to react with oxygen and other chemicals?
A. Unsaturated fats
B. Saturated fats
B. Saturated fats--> has a melting point of 149 degrees celcius.
Liquid at room temp
Found in a cis configuration
Molecules do not fit together and tend to spread into a thin layer?
A. Unsaturated fats
B. Saturated fats
A. Unsaturated fats
What test do we use to test for a leaky gut?
Mannitol and laculose test
T/F Lactulose is absorbed well by a healthy gut?
False, it is not well absorbed by the healthy gut
In a healthy gut we should see ___ levels of laculose and ___ levels of mannitol; in the URINE
low=lactulose
high= mannitol
Uses the same brain receptors as cocaine
Side affects are anorexia, decreased growth, visual disturbances, insomnia, depression, irritability, pyschosis
Ritalin (Methylphenidate HCl)
T/F: Ritalin is addictive
TRUE
What is a underlying factor of ADD/ADHD?
SX: Agitated upon waking up and before meals, usually feels better after eating
Triggers the adrenaline response
Hypoglycemia
Study where normal children were given sugar. Their ________ remained normal, but their _______ levels were 10 times higher than normal for up to 5 hours in all of the children.
A. Blood sugar/ Adrenaline (Yale study)
B. Adrenaline/ Blood sugar (Yale study)
A. Blood sugar stays the same and adrenaline levels go up 10 times
All of the following are management protocol for hypoglycemia except:
A. eat at least every 2 hours
B. Exercise at least 4-5 times a week.
C. Avoid sugar and other refined carbohydrates
D. GTT is usually not needed for diagnosis (Glucose Tolerance test)
B. Exercise at least 4-5 times a week.
What are 2 other underlying factors for ADD/ADHD?
1. Hypoglycemia
2. Allergies
3. Sensitivities
T/F: On the elimination diet, it is ok for the pt to have "just a little" of the food they are not supposed to eat..
FALSE: they can not have "just a little"
T/F: On the elimination diet, it is possible that the symptoms may worsen for 2 to 3 days from withdrawal.
TRUE
How long does the elimination diet last?
7-10 days
T/F: Many children with ADD/ADHD are Right Brain Tactile Learners?
TRUE
What are the symptoms for a person with learning differences?
1. Inattentive 2. Clumsy 3. Cant sit still 4. moody 5. always touching things 6. poor balance 7. Creative 8. Above average intelligence 9. inconsistent performance 10. Tired 11. poor reader
What are the treatments for a person with learning differences?
1. They need to touch something while learning (squeezable ball) 2. Touch them while talking 3. Simon says with rights and lefts 4. Cross crawl 5. Concentration with cards 6. Let them give directions when you drive 7. Sorting by color 8. Dribbling a basketball
Thyroid panel including TSH?
Hyperthyroid
What is the function of the gut?
1. Let good things in (Absorption and active transport)
2. Keep bad things out
Large undigested molecules called macromolecules pass through the intestinal wall into the bloodstream?
Leaky Gut
What type immunoglobulin is reduced in leaky gut causing increased susceptibility to infection and infestation?
IgA
What are the most common cause of leaky gut?
NSAIDS
What is leaky gut usually associated with?
Inflammation
How does one diagnose leaky gut?
The Lactulose and Mannitol Test
T/F: The Lactulose and mannitol test involves Lactulose and mannitol plus glycerol after an overnight fast. Followed by collecting urine for the next 6 hours
TRUE
What is the disaccharide that is not well abosorbed by the healthy gut?
Lactulose
What is the monosaccharide that is not metabolized and is normally carried across the gut wall by facilitated transport?
Mannitol
What type of transport does mannitol use?
Facilitated
T/F: Low lactose with high mannitol is suspect of a leaky gut
False: Low lactose/ high mannitol is a normal healthy gut
T/F: High lactose with low mannitol is suspect of a leaky gut?
TRUE
What do you do when you have leaky gut?
The 4R program
What are the 4 "R's"?
1. Remove
2. Replace
3. Repopulate (Re-inoculate)
4. Repair
1.Irritants/ Pathogenic Organisms
2. Hydrochloric acid/Digestive Enzymes/Intrinsic Factor
3. Friendly flora/Acidophilus/ Bifidus
4. Glutamine/Ilcorice/Cabbage/Slippery Elm

A. Repair
B. Replace
C. Remove
D. Repopulate
1-C
2-B
3-D
4-A
What is the gold standard for assessing HCl?
Heidelberg Capsule
Immediate, IgE mediated, Anaphylactic, Includes most food allergies.
A. Type 1
B. Type 2
C. Type 3
D. Type 4
A. Type 1
Cytotoxic to Rh
No food allergy
A. Type 1
B. Type 2
C. Type 3
D. Type 4
B. Type 2
Antigen/antibody complex
Rxn occurs 6 hrs to several days after exposure
A. Type 1
B. Type 2
C. Type 3
D. Type 4
C. Type 3
Delayed, Cell mediated, Graft rejections, some food allergies.
A. Type 1
B. Type 2
C. Type 3
D. Type 4
D. Type 4
What are the first 5 foods in order of their "Guilt"?
1. Egg--> 92.8%
2. Pork--> 63.8%
3. Onion--> 52.2%
4. Fowl--> 34.8%
5. Milk--> 24.6%
T/F: Avoiding coffee is a way to avoid pain?
TRUE
What does coffee bind to that releases pain?
Opiate receptors
What may enhance acupuncture analgesia?
D-Phenylalanine
What may reverse the tolerance to opiates and appears to raise pain threshold?
L-Tryptophan
T/F: Inflammation is directly related to the essential fatty acid pathway?
TRUE
What is the most abundant protein in the body?
Collagen
What is the primary purpose of collagen?
Tensile strength
What is the most abundant protein in the blood?
Albumin
What are the nutrients for repair? (9)
1. Glucosamine sulfate
2. D-glucuronic acid
3. alpha-ketoglutarate
4. Amino acids
5. Vitamin C
6. Vit E
7. Zinc/copper/manganese
8. Magnesium
9. Bioflavonoids
What stimulates the sympathetic nervous system and motor neurons?
Nociception
Anaerobic metabolism
Lactic acid build up
Hypoxia
causes atrophy of muscles, ligaments and bone
Hypomobility
Promotes inflammation
Increases pain
Increases vascular permeability
Impairs proteoglycan synthesis
Bradykinin
Acute and chronic inflammation
Atherosclerosis
Auto-immune disorders
Neoplastic disease
Cytokines
What can be reduced by an alkaline diet, omega 3 FA's, Antioxidants?
Bradykinin and cytokines
T/F: Even citrus fruits are alkalizing
TRUE
T/F: Proteolytic enzymes are good supplementation
TRUE
What parts of the body should be alkaline?
1. Blood
2. CSF
3. Interstitial fluid
4. Intracellular fluid
5.Lymph
What parts of the body should be acidic?
Inside the stomach during digestion
What restores the original pH of a soln when an acid or a base is added?
Buffer system
T/F: Buffer systems take seconds to balance the pH, Lungs take minutes, and kidneys take hours to days.
TRUE
What buffer operates outside the cell, is very powerful (1st gear), has a pk of 6.1, and requires sodium or other alkalizing minerals?
Bicarbonate buffer system
What buffer is Primarily inside the cell, uses potassium, has a pk=6.8?
Phosphate buffer system
What are examples of foods that leave an acid ash?
1. Animal flesh
2. Eggs
3. Dairy products
4. Most cereal grains
What foods leave an alkaline ash?
All veggies and most fruits (except plums, prunes, and cranberries)
T/F: Eat only acid ash foods for two days, then check the pH for the first urine of the third day (after at least 5 hrs of sleep)
TRUE
______urine is adequate mineral reserves. _________ urine is low mineral reserves
Acid urine= adequate mineral reserves
Alkaline urine= low mineral reserves