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188 Cards in this Set

  • Front
  • Back
In the first stage of heart development, what junction of veins thicken?
The walls of the ventral aorta and (paired) vitelline veins
At what intersection does the heart develop? What state is the blood in?
The ventral aorta with the paired vitelline veins; blood is deoxygenated
In the second stage of heart development, what occurs?
Common cardinals appear at the intersection of the vitelline veins and ventral aorta; walls continue to thicken
In the third stage of heart development, what occurs?
Intersection of vessels become a linear system of chambers (from bottom to top: sinus venosus, atrium, ventricle, conus arteriosus)
What is the direction of blood flow through the new linear system of chambers (stage 3 of heart development)?
1. Sinus Venosus
2. Atrium
3. Ventricle
4. Conus Arteriosus
What 4 inputs of blood come into the sinus venosus (stage 3 of heart development)?
- Paired cardinals
- Paired vitellines
Where does blood flow after the conus arteriosus?
Ventral Aorta
Which chamber receives O2 poor blood from the body and is the site of the heart beat initiation (in ancestral vertebrates)?
Sinus Venosus
Which chamber contracts to send blood to the ventricles?
Atrium
The atrium differs from the ventricle how?
Atrium - thinner walls, contraction weak
Ventricle - thicker walls, contraction strong
In stage 4 of heart development, what occurs?
The linear sequence of chambers folds so that the ventricle (and conus arteriosus) is ventral (atrium and sinus venosus fold behind out of view).
What is the atrium called in humans?
Auricle
In the development of the heart/circulatory system, what changed?
- Single circut --> Double circuit
- All blood in heart O2 poor --> blood in heart partitioned into O2 rich and O2 poor
Generally, how are chambers evolved to partition O2 rich and O2 poor blood?
With partitions
In the ancestral/embryonic condition, aortic arches are identified by what?
Roman numerals (constant to see homology, even when some AAs are lost) I-VI.
The ventral aorta extends cranially to become what?
External Carotid
The ancestral aortic arches procede dorsally to become what?
Dorsal Aorta
The internal carotids come from the (ventral/dorsal) side and flow into what structures?
Dorsal --> Aortic Arches --> Dorsal Aorta
In sharks, which of the aortic arches is lost? What does it become?
Aortic Arch I --> Part of Carotids (external and internal)
In sharks, what happens to aortic arches II-VI?
Split into two vessels, afferent and efferent branchials
What is the function of the afferent and efferent branchials in sharks?
In capillary beds of gills for O2 pickup
The afferent/efferent branchials are designated what (SHARKS)?
1-5 (anterior to posterior)
(AA II = A/E 1)
(AA III = A/E 2)
(AA IV = A/E 3)
AA V = A/E 4)
AA VI = A/E 5)
Carotids are not joined by what (in SHARKS)?
Aortic Arches
In teleosts, which aortic arches are lost? What do they become a part of?
AA I and II lost - become part of carotids
Are carotids more prominent in ancestral species or derived species?
More derived, as aortic arches are lost to become part of carotids.
In teleosts, how are the afferent and efferent branchials designated?
1-4 (anterior to posterior)
(AA III = A/E 1)
AA IV = A/E 2)
AA V = A/E 3)
AA VI = A/E 4)
Which species gave rise to tetrapods?
Lungfish (of Sarcopterygia)
What ecology gave rise to the air-breathing seen in lungfish?
1) Stagnant / Ephemeral H2O with little dissolved O2
2) Or in ocean
What circulation is seen in lungfish?
- Gills - if O2 rich water
- Lungs - if not using gills
From what did lungs evolve in lungfish?
Outpocketing of endoderm (pharynx) that never breaches to outside
In lungfish, what are 4 evolved features which help O2 flow?
1) Atrium divided by interatrial septum
2) Ventricle divided by interventricular septum
3) Conus Arteriosus has spiral valve
4) Pulmonary vein returns O2-rich blood
What kind of veins bring blood back to the heart (lungfish)?
Systemic veins via the sinus venosus
In lungfish, does the atrium or the ventricle have a complete partition?
- Atrium (interatrial septum) - keeps blood separate
- Ventricle (interventricular septum) - scaffold - doesn't prevent blood mixing completely
What is the purpose of the spiral valve seen in the conus arteriosus?
Keeps O2 rich and O2 poor blood separated when blood enters conus arteriosus / ventral aorta and AA system
Which vein returns oxygen rich blood to the left atrium?
Pulmonary veins
In lungfish, which of the aortic arches are used when the gills are active? Which are shut down?
Active: AA II, V, VI
Shutdown: AA III, IV (and pulmonary artery and vein)
Which of the ancestral aortic arches, in lungfish, become afferent and efferent branchials? Systemic arches?
A/E Branchials: AA II, V, VI
Systemic Arches: AA III, IV
In lungfish, which of the aortic arches are active when the lungs are active? Which are shut down?
Active: AA III, IV, VI (pulmonary artery - to lungs), pulmonary vein
Shutdown: AA II, V
Which of the ancestral aortic arches in lungfish is lost?
AA I --> Part of carotids
When lungfish are using their gills, what is the cycle?
Single Circuit pattern w/ A/Es; systemic arches shut down
What are the characteristics of the air breathing mechanism in lungfish?
1) Gills shut down (A/E receive little blood)
2) O2 poor blood to AA VI - modified to pulmonary artery which takes blood to lungs
3) New pulmonary vein takes O2 rich blood back to heart
4) O2 rich blood sent to body via systemics and external carotids
What do the 6 ancestral aortic arches correspond to in lungfish?
I = lost
II = 1 A/E
III = systemic arch
IV = systemic arch
V = 2 A/E
VI = 3 A/E
In lungfish, which vessel is introduced in the lung system?
Pulmonary vein which takes oxygen rich blood from lungs to heart
What are the three circuits in the lungfish?
1) Pulmonary Circuit
2) Systemic Circuit
3) Gill Circuit
What vessels are involved in the pulmonary circuit?
- Pulmonary Artery - going TO the lungs
- Pulmonary Vein - going FROM the lungs (*new)
Which ancestral aortic arch is shared in lungfish between the gills and lungs?
AA VI
What makes up the systemic circuit of lungfish?
- Vessels that do not form A/E
- Modified from AA III and IV
What is the function of the systemic circuit in lungfish?
To distribute O2 rich blood to the body
What makes up the gill circuit of lungfish?
- Vessels that form A/E
- AA II, V, VI
*AA VI facultative switch between lung and gill circuit*
In lungfish, which vessels takes O2 poor blood to the mouth?
External carotids
In lungfish, which vessels take O2 rich blood to the head?
Internal Carotids
Where do external carotids pick up blood on their way where?
Pick up blood in mouth via mouth lining; now O2 rich blood returns to body
Why is it important that internal carotids always carry O2 rich blood?
They are headed to the head!
What is unusual about the circulatory patterns of amphibians?
Living amphibians are oddballs because they are highly evolved from Labyrinthodonts, therefore there is no clear pattern.
In adult amphibians, which aortic arches are lost?
AA I-II, and V (always in frogs, sometimes in salamanders)
Which aortic arches remain in adult amphibians? How do they differ between salamanders and frogs?
AA III, IV, VI remain
(in salamanders - all A/E branchials)
(in frogs - no A/E branchials)
In salamanders, what links the pulmonary and gill circuits?
Aortic Arch VI
Do salamanders have systemic arches?
No, the remaining aortic arches are all afferent/efferent branchials.
What are the multiple sources of O2 uptake in salamanders?
- Gills
- Lungs
- Skin
How do salamanders obtain O2 through their skin?
Skin is membranous and can absorb O2 since they are bathed in O2 rich waters
Why is the inefficient separation of O2 rich and O2 poor blood not fatal in salamanders?
They are water-living, and typically live in O2 rich waters (constant uptake up O2)
The remaining aortic arches (III, IV, VI) of frogs define what three pathways?
- Carotid Complex
- Systemic Circuit
- Pulmonary Circuit
How is blood flow isolated to the carotids in frogs?
- Ductus Caroticus (portion of dorsal aorta between AA III and IV) is lost
How is blood flow isolated to the body in frogs?
- AA IV and dorsal aorta send blood from the Common Carotid to the body
What happens to the ancestral ventral aorta in frogs?
The portion between AA III and IV forms the common carotid
How is blood flow isolated to the lungs in frogs?
- Ductus Arteriosus (distal portion of AA VI) is lost; prevents it from connecting to the dorsal aorta
The Ductus Caroticus and Ductus Arteriosus are lost in which species?
Frogs (not in salamanders)
Frogs have what two circuits and complex?
- Carotid Complex
- Systemic Circuit
- Pulmonary Circuit
What makes up the carotid complex of frogs?
- AA III
- External and Internal Carotids
- Ventral Aorta anterior to AA IV (= Common Carotid)
What makes up the systemic circuit of frogs?
- AA IV
- Paired Dorsal Aortas
What makes up the pulmonary circuit of frogs?
- Proximal AA VI (distal part is lost - ductus arteriosus)
- Pulmonary Artery (homolog of AA VI)
- Pulmonary Vein (new vein)
What are some innovations of the amphibian heart?
- Shortened ventral aorta
- Bulbous Arteriosus (reduces tendency of O2 rich and low blood mixing in Ventral Aorta)
- Left ventricle contracts more strongly than RV
- Ventricular Trabeculae (reduces mixing between ventricles)
What are some mechanisms which reduce the mixing of O2 rich and O2 low blood in the amphibian heart?
- Shortened ventral aorta (drops blood pressure to prevent mixing)
- Bulbous arteriosus (bulging of ventral aorta which reduces the tendency of mixing)
- Ventricular trabeculae (mini walls coming out of floors of ventricles which reduces lateral mixing)
From what does blood enter the right atrium?
O2 poor blood from body enters sinus vinosus which goes into the right atrium
From what does blood enter the left atrium?
O2 rich blood from lungs (pulmonary veins) enters left atrium
What is the bulging expansion of the ventral aorta called which is new in frogs?
Bulbous arteriosus
Why does the left ventricle contract more strongly than the right ventricle?
Helps get the oxygenated blood up to the carotid complex and systemic arch
Where does the blood from the right atrium go? Is it O2 rich or poor?
O2 poor blood goes to the pulmonary artery
What paired openings leave the ventral aorta (anterior to posterior)? From what ancestral aortic arches do they evolve?
- Carotid Complex - AA III
- Systemic Arch - AA IV
- Pulmonary Artery - AA VI
What are 5 characteristics of adult reptilian circulation?
1) No gills
2) No ductus caroticus / arteriosus (independent carotid system and lungs)
3) Three blood pathways (carotid complex, systemic circuit, pulmonary circuit)
4) Heart may or may not have complete interventricular septum (complete in crocs)
5) Sinus Vinosus receives O2 poor blood
What is the first species to have a complete interventricular septum?
Crocodiles
The carotid complex of crocodiles emanates from what structure?
The ventral aorta on the left side of the heart (AA III)
What happens to the ancestral aortic arch IV in crocodiles?
Two distinct structures: left aorta and right aorta
Which side of the heart is the Left Aorta from?
From right side of heart; going to LEFT side
Which side of the heart is the Right Aorta from?
From left side of heart; going to RIGHT side
From what side of the heart do the pulmonary arteries leave?
Right side of heart
What three main vessels exit the heart of a crocodile?
- Pulmonary Arteries
- Left Aorta
- Right Aorta (to which the carotid complex branches off of)
What chamber is lost in the crocodile heart? Which three remain?
- No conus arteriosus / spiral valve
- Sinus venosus, atria, ventricles are still present
When the oxygen rich blood leaves the left ventricle, what is its path?
- Through semilunar valve
- Into Right Aorta (despite being on left side)
- May cross through Foramen of Panizza (to go to left aorta)
- Ascends up right aorta and may branch off to carotid complex
What is the hole that connects the left and right systemic aortas in crocodiles?
Foramen of Panizza
The crocodile has two significant pathways for blood depending on whether it is breathing air or submerged, what are the differences?
- Air-Breathing - returns O2 rich blood from lungs; higher pressure in LV; blood passes through foramen of panizza so O2 rich blood goes to left and right aortas
- Submerged - returns NO O2 rich blood from lungs; higher pressure in RV; O2 poor blood passes through foramen and mixes with O2 rich blood in R aorta; L aorta has only O2 poor blood
In comparing amniotes (reptiles, birds, mammals) what happens to the sinus venosus?
- Reptiles - SV complete and separate chamber
- Birds - SV reduced in size
- Mammals - SV gone
In comparing amniotes (reptiles, birds, mammals) where is the placement of the Sino-Atrial node?
- Reptiles - On Sinus Venosus
- Birds - Resides in R. Atrium
- Mammals - Resides in R. Atrium
In comparing amniotes (reptiles, birds, mammals), which of right and left aortas is present?
- Reptiles - both are present
- Birds - single R Aorta
- Mammals - single L Aorta
In comparing amniotes (reptiles, birds, mammals), where does the carotid complex branch off of
- Reptiles - off of R Aorta
- Birds - off of R Aorta
- Mammals - off of L Aorta
Birds, Mammals, and some Reptiles (crocodiles) always have a what structure which is not complete in those ancestral to them?
Interventricular septum
What happens to the original, ancestral four chambers of the heart (in amniotes)?
- Lose Sinus Venosus
- Retain Atrium (splits in two)
- Retain Ventricle (splits in two)
- Lose Conus Arteriosus
In mammals, the L aorta is maintained, which side of the heart does this come off of?
Left (O2 rich) side
Which vessel sends O2 rich blood to the arms?
Subclavians
The base of the right subclavian in adult mammals in a remnant of which aortic arch?
Right IV AA
What does the term brachiocephalic refer to?
Subclavian (specifically the right one) being attached to a shared vessel (brachiocephalic artery, BA) with the common carotid
Are mammals typically brachiocephalic or non brachiocephalic? What are the exceptions?
- Not Brachiocephalic (subclavians not connected to common carotid)
- Internal and External carotid pairs both extend off of single common carotid
- Exceptions: Cats and Humans
What makes cats brachiocephalic pattern unique from the typical nonbrachiocephalic pattern of most mammals?
Brachiocephalic, right subclavian is attached to common carotid, forms the brachiocephalic artery (BA) which branches to the CC and RS
What makes humans brachiocephalic pattern unique from the typical nonbrachiocephalic pattern of most mammals?
Not typical common carotid (internal and external carotid pairs ares split, no longer attached to same vessel); right subclavian is attached to I and E common carotid on right side, forming a new brachiocephalic artery
What is the predicted "brachiocephalic" condition for carotid draining patterns?
- Internal and External carotids pairs will be separated to have two attachments (each w/ I and E)
- Right and Left subclavians will attach to Left aorta separately (therefore NOT brachiocephalic)
- This would maximize blood flow to head
What may be a reason why the predicted condition of carotid / subclavian drainage pattern has not come about?
This maximized flow of blood to the head would cause bigger brains; however it is necessary that brains only reach a certain size for giving birth
Which set of veins form a large H shape centering at the heart (in the ancestral/embryonic model)?
Cardinals (common, anterior, posterior)
Which vein is unpaired and carries blood to the left vitelline (in the ancestral/embryonic model)?
Subintestinal vein
Which paired veins flow into the subclavian and drain the hindlimbs via the iliac?
Lateral abdominals
How do sharks venous system change compared to the ancestral/embryonic model?
- Renal Portal formed from posterior cardinal
- Hepatic Portal formed from subintestinal
- Systemic Hepatics form from vitellines
-
Specifically, what happens to the posterior cardinal in evolving to the SHARK?
- Loss of piece of posterior cardinal above the kidney
- Splits veins into two pieces (portion still connected to the common cardinal = Posterior Cardinal; portion attached to kidneys which joins posteriorly = Renal Portal)
What does the formation of the renal portal do to blood flow of the shark?
Blood in posterior cardinal must flow through kidney before returning to heart
(*this change does not persist throughout evolution*)
What happens to the subintestinal vein of the ancestral/embryonic model as it evolves to the shark and future species?
- Subintestinal vein invests in liver once formed; terminates here (as opposed to a vitelline vein)
What happens to the vitellines of the ancestral/embryonic model as it evolves to the shark and future species?
Vitellines become sinusoids in liver (channels for blood in soft organs) => Systemic Hepatics
In the ancestral condition, what was the path of blood through the kidneys?
- Renal artery dumps O2 rich blood in kidney
- Posterior cardinal picks up O2 poor blood from kidney
*One rinse cycle for blood*
In the derived condition, what is the path of blood through the kidneys?
- Renal artery dumps O2 rich blood in kidney
- Posterior cardinal picks up O2 poor blood from kidney
- Renal portal dumps O2 poor blood in kidney
*Two rinse cycles for blood*
Which features which evolve in sharks are conserved on through mammals?
- Hepatic portals
- Systemic hepatics
Which three venous structures are reduced or eliminated in tetrapods (become part of vena cava)?
- Cardinals
- Renal Portals
- Lateral Abdominals
What new venous structure is derived in tetrapods?
Posterior Vena Cava (postcava)
Which major vessel is the new path for blood to return to heart from the posterior portion of the body?
Posterior Vena Cava
In embryonic tetrapods, which structure that is eliminated in adults, continues to function embryonically?
Old lateral abdominals
What derived features are seen in the venous circulation of larval frogs and adult salamanders?
- Lateral Abdominals --> Ventral Abdominal (unpaired, portal to liver)
- Posterior Vena Cava (derived from posterior cardinals and systemic hepatics; flows directly to sinus venosus)
Where does the posterior vena cava flow to (salamanders, frogs, reptiles and birds)?
Sinus Venosus of heart
What is the function of the posterior vena cava?
Allows blood in posterior body to return more directly back to the heart
Sharks evolve a renal portal to pass blood through the kidneys, in which species does this evolution revert back to the single systemic renal vein which flows into the postcardinal (i.e., not portal)?
Adult Salamanders and Larval Frogs
In adult frogs, what are the newly derived features?
- No posterior cardinals (causes formation of Renal Portal, as seen in shark)
- Ventral abdominals (unpaired, portal into liver, same as in larval frog/adult salamander)
- Posterior vena cava (vessel returning caudal blood to heart)
What three inputs go into the heart of the adult frog?
- Post cava
- Right common cardinal
- Left common cardinal
The anterior cardinals of ancestral vertebrates are homologous to what structure?
Jugulars
The common cardinals of ancestral vertebrates are homologous to what structure?
Precavas
In adult reptiles and birds, which ancestral features of the venous circulation are maintained?
- Renal Portal (incomplete)
- Lateral Abdominals (again paired as in sharks!)
In adult reptiles and birds, which features of the venous circulation are derived?
- Renal Portal (some vessels bypass kidney)
- Lateral Abdominals (portal in liver, instead of to subclavian)
- Sinus Venosus receives all caudal blood via postcava
In adult reptiles and birds venous circulation, what ways can caudal blood return to the heart?
- Via renal portal (to postcava)
- Via posterior vena cava bypass of kidney
- Via lateral abdominals which are portal in liver (to postcava)
In the venous circulation of adult mammals, which ancestral paired anterior veins remain?
- Precavas (unpaired in some)
- Jugulars
- Subclavians
In the venous circulation of adult mammals, what are the derived features?
- No sinus venosus (blood returns to right atrium from body via...)
- Postcava directly empties into right atrium
- Posterior cardinals reduced (L=hemiazygous; R=azygous) and drain rib cage into postcava
- No renal portal
- No abdominal stream
When evolutionarily does the sinus venosus disappear? Where does blood get dumped then?
Adult mammals
- Blood gets dumped from postcava into the right atrium
When do the hemiazygos(L) and azygos(R) appear? What are they homologous to? What is their function?
Appear in adult mammals; reduced posterior cardinals; drain rib cage into postcava
In venous circulation of adult mammals, what is the only route for systemic blood to return to the heart? What is incorporated into this vein?
Posterior Vena Cava
- Posterior Cardinals (azygos, hemiazygos)
- Systemic Hepatics
- Renal Portal (absent except for this portion)
Mammals (except for cats and humans) have how many routes for venous blood TO the heart? What are they?
3: Right precava, Left precava, Postcava
How many routes for venous blood TO the heart do cats and humans have? What are they?
2: Right precava and Postcava
What features are lost in human and cat venous systems?
- Hemiazygos
- Left Precava (partially-coronary sinus)
In humans and cats venous systems, what is added?
- Brachiocephalic Vein (brings anterior blood from left side (jugular and subclavian) to the right precava to enter right atrium)
- Coronary Sinus (pouch on surface of heart; homolog of L precava)
What is the function of the coronary sinus?
- Pouch on surface of heart which is homologous to the left precava
- Drains myocardium and returns it to right atrium
Embryos of mammals have what venous drainage patterns?
- Cardinals (anterior/common/posterior)
- Many crossover vessels (R-L) between corresponding cardinals
- Retention of one cross-branch produces brachiocephalic shunt
In reptile and bird embryos, there are two significant paired veins; what are they?
- Lateral Abdominals (drain hindlimbs, O2 poor, empty into heart, SV)
- Allantoic Vein (brings O2 rich blood from allantois, drains into abdominal stream)
What is the concentration of O2 in blood in reptile and bird embryos as it is returned to the heart (SV)?
Diluted O2 blood delivered to heart (O2 poor blood from hindlimbs dilutes the O2 rich blood from allantoic vein in the lateral abdominals)
What is the imperfection of the reptile and bird embryo system?
Fully oxygenated blood from allantois never distributed at O2 rich concentration b/c diluted by blood from lateral abdominals
What happens to the lateral abdominals in adult reptiles?
Portal into liver; drains hindlimbs only (O2 poor blood); doesn't mix with allantoic vein since not embryo
In adult reptiles, what takes oxygen poor blood from the liver to the heart (SV)?
Posterior vena cava
What happens to the lateral abdominals in adult birds?
Turns into inferior mesenteric ligaments; do not carry blood
In adult birds, what is the homolog to the lateral abdominals?
Inferior Mesenteric Ligaments
In embryonic mammals, what is the umbilical vein derived from?
Ancestral abdominal stream and allantoic vein
What is the function of the umbilical vein?
Picks up O2 rich blood in placenta and takes to Sinus Venosus of heart
In embryonic mammals, where is the O2 rich blood from the umbilical vein diluted?
At liver by the posterior vena cava which is draining O2 poor blood
What houses the umbilical vein?
Umbilical Chord
What three things is the placenta composed of?
- Maternal Tissues (mother)
- Allantois (embryo)
- Chorion (embryo)
What is the function of the placenta?
Exchange of O2 and metabolites between mother and embryo
What is the portion of the umbilical vein which is found in the liver?
Ductus Venosus
What happens to the ductus venosus and umbilical vein in adults?
DV => Ligamentum Venosus
UV => Ligamentum Teres (round ligament)
What is the abdominal stream in embryonic mammals? In adult mammals?
Umbilical Vein in embryo
No abdominal stream in adults
The abdominal stream of the mammal fetus does what?
Carries O2 rich blood in embryo; associated with vessel draining extra-embryonic membrane
What happens to the adult aortic arches in mammals?
Reduction of embryonic arches
What is the embryonic environment of mammals?
Amnion fluid-filled cavity
Lungs shut down
What is the route of blood through fetal structures of mammals, beginning at the placenta up until the right atrium?
- O2 rich blood passes through umbilical vein to liver
- Diluted with O2 poor blood from Hepatic Portal Vein (some) and Postcava (all) @Ductus Venosus
- 1x diluted blood flows up postcava to Right Atrium
What is the route of blood through fetal structures of mammals, beginning at the right atrium (coming from postcava) until it leaves through the ascending branch of the left aorta?
- 1x diluted blood flows into right atrium past flap (remnant of sinus venosus) which regulates flow
- Blood shoots across right atrium through Foramen Ovalae into left atrium
- Enters Left ventricle
- Leaves through ascending branch of L aorta
What is the route of blood through fetal structures of mammals, beginning at the right atrium (enters from anterior venacava) until it gets to the Ductus Arteriosus?
- O2 poor blood enters right atrium from anterior vena cava
- Flows into right ventricle
- Enters Pulmonary Trunk (which would usually go to lungs, but they are closed)
- Flows past lungs to Ductus Arteriosus (distal AA VI)
What is the route of blood through fetal structures of mammals, as blood leaves the ascending branch of the left aorta back through to the placenta?
- 1x diluted blood can go anteriorly to the carotid complex/left carotid
- Diluted second time by O2 poor blood in ductus arteriosus
- Enters aorta where blood can be sent to arteries of body
- Blood enters umbilical artery on way back to the placenta (returns 2x diluted)
What is the hole between the two atriums of the fetal circulation in mammals? What is its significance?
- Foramen Ovalae - 1x diluted blood from postcava shoots through here to get to left atrium
Where is the ductus venosus found?
Between the Hepatic Portal Vein and the Postcava (from umbilical vein)
Where is the Ductus Arteriosus found?
Portion of pulmonary trunk past the lungs which connects to the descending branch of the aorta
How diluted is the blood which is sent to the carotid complex in embryonic mammals?
1x diluted (with blood from precava); best possible is sent here, although this dilution probably limits brain growth (birthing...)
What changes happen to the mammal fetus once it takes its first breath?
- Nerve impulse triggered to cause ductus arteriosus to shrivel into ligament
- Foramen Ovale closes to form wall (fossa ovalae)
- Umbilical artery and vein = chord, severed from outside (artery becomes ligament between naval and bladder)
- Ductus venosus shrivels into ligament
What happens to the ductus arteriosus and ductus venosus at the moment fetuses take their first breath?
Both shrivel up into Arterial ligament and Ligamentum Venosus respectively.
What happens if the Foramen Ovalae doesn't completely close up at the first breath of the baby mammal?
Heart Murmur
Which ligament can be felt between the naval and the bladder?
Ligament from the umbilical artery shriveling up at first breath
What are the three basic features of the nervous system?
1. Stimulus @ Receptor - sense organ
2. Impulse @ Conductor - neuron
3. Response @ Effector - muscle or gland
Prior to the neuron, what ancestral structures could have existed?
- Neuromuscular cell - one structure; combines all three components of N.S. (receptor, conductor, effector) - hypothetical
- Neurosensory Cell - one structure; combines two components of N.S. (receptor and conductor) - found in nasal epithelium
What are the two functional types of neurons found in vertebrates?
- Sensory Neurons
- Motor Neurons
What is the structure of a sensory neuron?
- Dendrite to cell body (receptor)
- Cell Body (outside of CNS in sensory neuron)
- Axon from cell body to inside CNS
What is the structure of a motor neuron?
- Cell body located in CNS
- Axon extends out of CNS to effector (muscle or gland)
What is the structure of association neurons?
Entire neuron located inside of CNS; including cell body
What is the function of association neurons?
- Carry impulse up (ascending) or down (descending) CNS
- Carry impulse across (L-R) CNS (decussation)
- Complete simple reflex pathway outside brain (in spinal cord)
What do "Decussating Fibers" do? Where are they found?
Found in Association Neurons - carry impulses across from one side of the body to the other so body knows what is happening
Which type of neurons can have multiple dendrites and axons?
Motor and Association Neurons
Which type of neurons have only a single dendrite and axon per cell body?
Sensory Neurons
How can the impulse of neurons be sped up?
Myelin sheath blocks form donuts around the axon allowing the impulse to jump between
What color do axon cylinders look? What color does myelin look?
Axon Cylinder - grey
Myelin - white
What cells are associated with Myelin production?
- Glial Cells - inside CNS
- Schwann Cells - outside CNS
What is myelin made out of?
Fatty white looking cells