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59 Cards in this Set

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capillary hemangioma (juvenile hemangioma) of the skin of newborns - "AKA"
strawberry
As compared with capillary hemangiomas, WHAT HEMANGIOMAS are less circumscribed and more frequently involve deep structures.
Cavernous hemangiomas

large, dilated vascular channels
Polypoid exophytic red nodule on oral mucosa or gingiva which bleeds and ulcerates easily.
- A lobular capillary hemangioma.
Pyogenic granuloma
granuloma gravidarum AKA
pregnancy tumor

- pyogenic granuloma in 1% of pregnant women
cavernous
what type of hemangioma?
juvenile hemangioma "strawberry type"
What type of hemangioma?
pyogenic granuloma
What's this?
hemangioma of the tongue
What's this?
What is pedunculated?
means "having a stalk or peduncle".
cavernous lympohangioma AKA
cystic hygroma
genetic disease that that often is coincident with cystic hygroma
Turner syndrome
aquired lymphangioma AKA
lymphangiectasia
when might your patient have lyphangiectasia?
Usually after breast cancer with axillary dissection or
radiation.
Hemangioma
Mucocele
vesiclul-bullous eruptions
brachial cleft cyst
thymic cyst
laryngeocele
thyroid mass (goiter)
lipoma
What's the differential diagnosis?
How do you treat cystic hygroma?
remove surgically
why does cystic hygroma come back after removal?
no encapsulation
a specialized arteriovenous anastomosis that is involved in thermoregulation
glomus body
where are glomus tumors found?
They are most commonly found in the distal portion of the digits, especially under the fingernails.
glomus tumor - excise it
How do you treat this?
port wine stain is associate with what syndrome
Sturg-Weber
which fades, nevus flemmus or port wine stain
nevus flemmus
vascular ectasia assoc with hyperestrinism
spider telangiectasia
what happens when you press a spider telangiectasia
blanching
nerve pattern of Sturg-Weber?
trigeminal
Sturg-Weber syndrome often includes what problem ipsi lateral to a port wine stain?
Brain vascular malformation in leptomeninges over cortex
Hereditary Hemorrhagic Telangiectasia
Osler-Weber-Rendu Disease
Glaucoma is coincident with 10% of facial capillary malformations (no brain involvement). It is 27-45% concident when the malformations are where?
skin supplied by both the ophthalmic and
the maxillary divisions CN V
Diagnosis of osler-weber-rendu
triad of
1)telangiectasia,
2)recurrent epistaxis, and
3)a positive family history for the disorder.
The major cause of morbidity and mortality due to this disorder of osler-weber-rendu
multiorgan AVMs and the associated hemorrhage that may accompany them.
treatment of osler-weber-rendu
Treatment mainly is supportive and consists of controlling and
treating the bleeding.
bleeding concerns with osler-weber-rendu
Nosebleeds
Hematuria
GI bleed

(bloody tears - just freaky)
Osler-weber-rendu has a higher incidence where geographically?
Danish island of Fyn, the Dutch Antilles, and parts of
France.
The main defect in some families with osler-weber-rendu
mutation of the protein endoglin (chromosome 9q34), a receptor for transforming growth factor beta, which has a role in tissue repair and angiogenesis.
AVMs in diff organs cause what different problems
lung: right-left shunt, hemoptysis, stroke, brain abcess (filtering lost in lung)
brain: HA
GI: melena, ab pain
Liver: jaundice, RUQ pain, HOCF (L-R shunt in liver), atypical cirrhosis, esphageal varices bleeding
Skin: telangiectasias
Type of anemia experienced by osler-weber-rendu pt
iron deficiency
Opportunistic infection of AIDS
Bacillary Angiomatosis
vector of Bartonella Henselae?

vector of Bartonella quintana?
cat flea

human body louse
4 patterns of Bacillary Angiomatosis
Globular angiomatous papules or nodules resembling pyogenic
granuloma
a disease caused by Bartonella
infection,
NVD, fever, hepatosplenomegaly,
bone pain from a destructive bone mass may occur,
Weight loss and lymphadenopathy
Peliosis hepatis
Various unrelated conditions
have been reported to be
associated with peliosis hepatis,
the most important of them
being the administration of what hormones?
steroid hormones.
peliosis hepatitis
This is a liver, with blood filled cavities. The patient has a history of cat-scratch fever and steroid hormone therapy. What disease is this?
In bacillary angiomatosis, capillaries having protuberant
Atypical epitheliod endothelial cells with nuclear atypia and mitosis in an acute inflammatory background containing “DUST” . What is the dust?
the bacillus
Borderline Vascular tumors
Kaposi’s sarcoma
four forms of Kaposi's sarcoma
Chronic (classic or European)
type of kaposi's among Ashkenazi jews
chronic
how do the skin lesions develop in chronic Kaposi's?
spread from distal extremities to proximal
Kaposi's occuring in Young Bantu kids (South Africa)
African
type of Kaposi's: Pts. Who received a solid organ
transplant and are on high dose chemo
transplant
These lesions may be the forme fruste of the
underlying AIDS which has not been
diagnosed.
Kaposi's - AIDS
virus playing a major role in Kaposi's sarcoma etiology
human herpesvirus type 8
a wide spectrum of vascular neoplasms
showing histologic and clinical behavior intermediate
between hemangioma and angiosarcoma.
Hemangioendothelioma (HE)
Differential diagnosis with Hemangioendothelioma (HE)
Carcinoma, Melanoma, Sarcoma
Malignant vascular tumors
Angiosarcoma (AS)
Malignant endothelial neoplasm that may
resemble a spectrum of tumors from
hemangioma to carcinoma to melanoma.
Angiosarcoma (AS)
Liver Angiosarcoma is associated with:
Arsenic
Staining for _______________ may need to be demonstrated before a
definitive dx of Angiosarcoma can be made.
CD31 or von Willebrand
factor
Derived from the elusive pericyte.
Hemaniopericytoma (HPC)
Stain used for Hemaniopericytoma (HPC)
Silver stain highlights the reticulin sheath that surrounds each
cell and confirms that the tumor cells are outside the vascular
spaces.
hemangiopericytoma
?