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26 Cards in this Set

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Usual interstitial
pneumonia-UIP:

The patient with UIP is usually a ______.
smoker
Usual interstitial
pneumonia-UIP:
On HRCT
scan, most of the lesions are typically worse at the
______ of the lung and in the periphery, under the
pleura.
base
Usual interstitial
pneumonia-UIP:

microscopically, you see interstial _______
fibrosis
Bronchopulmonary Lavage:

Where is the scope wedged?
The bronchoscope is wedged into a distal bronchus
What lab technique would you use to separate sarcoid and hypersensitivity
type diseases (lymphocyte predominant-type) from
idiopathic pulmonary fibrosis (neutrophil predominant-
type).
Differential cell counts
The bronchogenic cyst is a mediastinal mass
which is attached to the ______.
trachea
What is an additional
segment of lung which develops from an
abnormal accessory lung bud.
The pulmonary sequestration
What is a relatively common
developmental lesion composed of disorganized
pulmonary tissues -mostly bronchial epithelium and
cartilage. It typically presents in adult life as-a small "coin
lesion."
The pulmonary hamartoma
What do you do with a coin lesion
It is typically removed to rule out early lung cancer.
What type of Resp system dz?

(synonym -Hyaline Membrane
Disease).
Respiratory Distress Syndrome
(RDS) of the Newborn (premature)
Classical Goodpasture's syndrome is a syndrome in which
the patient presents with the combination of ______
hemoptosis and
hematuria.
Classical Goodpasture's syndrome symptoms
due to circulating antibodies directed against the
collagen component of pulmonary and renal _____
basement
membrane.
What granulomotosis which may sometimes mimic
Goodpasture's syndrome?
Wegener's granulomotosis
Wegener's Granulomatosis May present with ______
a pulmonary hemorrhage and renal
disease.

hemoptosis and
anemia
Wegener's Granulomatosis involves structures in the ____
(a) upper midline
(nose, sinus, nasopharynx); (b) lung; and (c) kidney.
Wegener's Granulomatosis:
There is a necrotizing vasculitis of the ____ arteries.
small
Wegener's Granulomatosis:
These patients have autoantibodies directed against
neutrophil cytoplasm. They are called ____
anti-neutrophil
cytoplasmic autoantibodies (cANCA).
Primary (idiopathic) pulmonary hypertension which is mostly a
disease of what people?
young women (20-40).
Secondary pulmonary hypertension -usually the result of
_______
cardiac disease (left ventricular failure. mitral valve disease,
congenital malformations), or pulmonary disease (COPD. fibrosing
lung disease, or recurrent pulmonary emboli).
______ is a chronic inflammatory disorder of the airways in
which many cells and cellular elements play a role, in
particular, mast cells, eosinophils, T lymphocytes,
macrophages, neutrophils, and epithelial cells.
Asthma
Asthma:
recent evidence indicates that subbasement
membrane _______
-->contribute to persistent
abnormalities in lung function
fibrosis
Asthma:
Airway hyperresponsiveness leads to clinical symptoms of
wheezing and dyspnea after exposure to _____
allergens,
environmental initants, viral infections. cold air. or exercise.
Airway hyperresponsiveness
can be measured by inhalation challenge testing with
________, as well as after exposure to such
nonpharmacologic stimuli as hyperventilation with cold dry
air, inhalation of hypotonic or hypertonic aerosols, or after
exercise.
methacholine or histamine
______ appears to reflect airway
hyperresponsiveness and may serve as a measure of airway
hyperresponsiveness, asthma instability, or asthma severity.
variability between morning and evening peak
expiratory flow(PEF)
Acute bronchoconstriction.
caused by____
1) Allergen-induced acute bronchoconstriction (IgE)
2) Aspirin and other NSAIDS (non IgE)
3) exercise, cold air, and
irritants,
Airway remodeling :
airway obstruction may
be persistent and not responsive to treatment why?
an alteration in the amount and
composition of the extracellular matrix in the airway wall.