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26 Cards in this Set
- Front
- Back
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Usual interstitial
pneumonia-UIP: The patient with UIP is usually a ______. |
smoker
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Usual interstitial
pneumonia-UIP: On HRCT scan, most of the lesions are typically worse at the ______ of the lung and in the periphery, under the pleura. |
base
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Usual interstitial
pneumonia-UIP: microscopically, you see interstial _______ |
fibrosis
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Bronchopulmonary Lavage:
Where is the scope wedged? |
The bronchoscope is wedged into a distal bronchus
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What lab technique would you use to separate sarcoid and hypersensitivity
type diseases (lymphocyte predominant-type) from idiopathic pulmonary fibrosis (neutrophil predominant- type). |
Differential cell counts
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The bronchogenic cyst is a mediastinal mass
which is attached to the ______. |
trachea
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What is an additional
segment of lung which develops from an abnormal accessory lung bud. |
The pulmonary sequestration
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What is a relatively common
developmental lesion composed of disorganized pulmonary tissues -mostly bronchial epithelium and cartilage. It typically presents in adult life as-a small "coin lesion." |
The pulmonary hamartoma
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What do you do with a coin lesion
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It is typically removed to rule out early lung cancer.
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What type of Resp system dz?
(synonym -Hyaline Membrane Disease). |
Respiratory Distress Syndrome
(RDS) of the Newborn (premature) |
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Classical Goodpasture's syndrome is a syndrome in which
the patient presents with the combination of ______ |
hemoptosis and
hematuria. |
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Classical Goodpasture's syndrome symptoms
due to circulating antibodies directed against the collagen component of pulmonary and renal _____ |
basement
membrane. |
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What granulomotosis which may sometimes mimic
Goodpasture's syndrome? |
Wegener's granulomotosis
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Wegener's Granulomatosis May present with ______
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a pulmonary hemorrhage and renal
disease. hemoptosis and anemia |
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Wegener's Granulomatosis involves structures in the ____
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(a) upper midline
(nose, sinus, nasopharynx); (b) lung; and (c) kidney. |
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Wegener's Granulomatosis:
There is a necrotizing vasculitis of the ____ arteries. |
small
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Wegener's Granulomatosis:
These patients have autoantibodies directed against neutrophil cytoplasm. They are called ____ |
anti-neutrophil
cytoplasmic autoantibodies (cANCA). |
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Primary (idiopathic) pulmonary hypertension which is mostly a
disease of what people? |
young women (20-40).
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Secondary pulmonary hypertension -usually the result of
_______ |
cardiac disease (left ventricular failure. mitral valve disease,
congenital malformations), or pulmonary disease (COPD. fibrosing lung disease, or recurrent pulmonary emboli). |
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______ is a chronic inflammatory disorder of the airways in
which many cells and cellular elements play a role, in particular, mast cells, eosinophils, T lymphocytes, macrophages, neutrophils, and epithelial cells. |
Asthma
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Asthma:
recent evidence indicates that subbasement membrane _______ -->contribute to persistent abnormalities in lung function |
fibrosis
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Asthma:
Airway hyperresponsiveness leads to clinical symptoms of wheezing and dyspnea after exposure to _____ |
allergens,
environmental initants, viral infections. cold air. or exercise. |
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Airway hyperresponsiveness
can be measured by inhalation challenge testing with ________, as well as after exposure to such nonpharmacologic stimuli as hyperventilation with cold dry air, inhalation of hypotonic or hypertonic aerosols, or after exercise. |
methacholine or histamine
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______ appears to reflect airway
hyperresponsiveness and may serve as a measure of airway hyperresponsiveness, asthma instability, or asthma severity. |
variability between morning and evening peak
expiratory flow(PEF) |
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Acute bronchoconstriction.
caused by____ |
1) Allergen-induced acute bronchoconstriction (IgE)
2) Aspirin and other NSAIDS (non IgE) 3) exercise, cold air, and irritants, |
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Airway remodeling :
airway obstruction may be persistent and not responsive to treatment why? |
an alteration in the amount and
composition of the extracellular matrix in the airway wall. |
