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7 Cards in this Set

  • Front
  • Back
Asthma is a polygenic disorder which results from an initial exposure to an
_____.
“allergen”
Difficulty breathing results from the type ____ hypersensitivity reaction involving
constriction of respiratory smooth muscles, increased mucous production,
edema and inflammatory cell infiltration.
I
In chronic cases, airway tissue is ______ with smooth muscle
hypertrophy, basement membrane fibrosis, edema and inflammatory
infiltrate (eosinophilia is significant).
“remodeled”
______ deviation is responsible for Ig-E isotype response to the “allergen”.
Th2
____-cells are responsible for driving the asthmatic attack (histamines) as
well as later development of responses (cytokines).
Mast
Treatment involves identifying “allergens” and use of anti-inflammatory
agents (such as ______,…).
antihistamines, bronchodilators
Immunotherapy would involve deviating T cell response from Th2 to Th1 to
eliminate _______ of mast cells.
“sensitization”