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15 Cards in this Set
- Front
- Back
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List five reversible dementias?
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1. alcholic dementia
2. normal pressure hydrocephalus 3. drug toxicity 4. pseudodementias 5. dementias caused by nutritional defects |
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In Alzeheimers, what neuronal system has a lot of degeneration?
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The cholinergic neurons in the "nucleus basalis of Meynert"
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What is the major genetic problem found in familial alzheimers?
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Increased production of amyloid precursor proteins.
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What are type of drugs are tacrine (Cognex), Aricept, and Exelon?
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Cholinergic degradation inhibitors used to treat Alzheimers.
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What is Cevimeline?
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A direct cholinergic agonist used to treat Alzheimers.
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For Alzeheimers disease, what three things can be given to the patient either prior to the disease or right at the onset as preventative medicine?
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1. PRESENLINS 1 and 2
2. Estrogen 3. NSAIDS |
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What is Ciliary neurotrophic factor given to treat?
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Huntington's disease
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What is Riluzole and what is it given to treat?
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Riluzole is a Na channel blocker given to treat Px with Amyotrophic Lateral Sclerosis (ALS). It prolongs life.
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Four dementias due to cardiovascular disorders are:
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1. Atherosclerosis (large vessel)
2. arteriosclerosis (small vessel) 3. Embolisms 4. Strokes |
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What is the treatment for Atherosclerosis induced dementia?
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Diet and anti-hyperlipoproteinemia drugs (clofibrate, cholestyramine, "STATINS")
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What type of drugs are given to treat arteriosclerosis?
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Anti-hypertensives
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What two drugs are given in the acute treatment of non-hemorrhagic strokes?
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Recombinant tissue plasminogen activator (rt-PA)
and Streptokinase |
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What is given to reduce hypothyroidism induced dementia?
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Synthroid
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What is given to reverse Cushing's syndrome induced dementia?
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Mifepristone (glucorticoid antagonist)
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When you are doing a work up for Alzheimers disease what two types of neuroimaging are ordered?
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Head CT scan without contrast
Head MRI without contrast |
