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20 Cards in this Set
- Front
- Back
posterior pituitary is derived from....
anterior from... |
neuroectoderm
oral ectoderm (Rathke's pouch) |
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alpha subunit is common to
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"fat hal"
FSH TSH hCG LH |
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oxytocin & ADH are made in the _ nuclei
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supraoptic & paraventricular nuclei
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organs that don't need insulin for glucose uptake
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"BRICK L"
brain RBCs intestine & beta-Islets cornea kidney liver |
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elevation in ATP inside beta-islet causes... (5)
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**closure** of K+ channel
depolarization ^ Ca++ exocitosis of insulin |
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does K+ channel close or open, inside beta-islets?
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closes
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glut-2 is bidirectional & services what tissues?
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"BILK" i.e., these tissues cheat the system and get glucose!
beta-islets small Intestine liver kidney |
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somatostatin from the hypothalamus --> ?
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inhibits GH, TSH secretion
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_ treats a prolactinoma.
_ stimulates prolactin secretion |
bromocryptine (a dopamine agonist)
dopamine antagonists (most antipsychotics) and estrogens |
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bromocryptine is a _
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dopamine agonist
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17-alpha hydroxylase deficiency (4)
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^ mineralocorticoids --> hypertension, hypokalemia
XY: v DHT --> pseudohermaphroditism. externally female MIH --> no internal reproductive structures XX: lacking 2^ sexual characteristics |
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the most common adrenal enzyme deficiency
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21-hydroxylase
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21-hydroxylase: 2 themes
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^ sex hormones (low cortisol & mineralocorticoids)-->
1) masculinization, female pseudohermaphroditism 2) HYPOtension/volume depletion/(salt wasting--> shock in newborns) , hyperkalemia, ^ renin |
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one lesion that can disrupt CRH release
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supraChiasmatic nucleus; Circadian; CRH
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PTH --> _ in osteoblasts
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M-CSF
RANK-L |
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(4) --> low Mg++
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DADA
diarrhea aminoglycosides diuretics alcohol abuse |
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3 things that regulate PTH
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v Ca++ --> ^ PTH
^ Ca++ --> v PTH v Mg++ --> v PTH |
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4 regulators of Vit D
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PTH, low Ca++, low phosphate
--> ^ vitamin D production Vit D --> v vitamin D production |
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cAMP signaling hormones
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FLAT CHAMP gCG
fsh, lh, acth, tsh crh, hcg, adh v2, msh, pth ghrh, calcitonin, glucagon |
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cGMP signaling hormones
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ANP, NO
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