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9 Cards in this Set
- Front
- Back
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What is the distribution of individuals with Bipolar Disorder and what is associated with each type?
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1.3% of US population
0.8% are Bipolar I - Intense episodes of mania, but less severe episodes of depression 0.5% are Bipolar II - Hypomania with more severe episodes of depression ?% Bipolar III - Persons who have a first dgree relative with bipolar. |
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What is the suicide rate for bipolar disorders?
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25% attempt and 15% success
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What is the core feature of atypical depression?
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Mood Reactivity in addition to two of the following:
Significant weight gain or increased apetite Hypersomnia Leaden paralysis Long standing pattern of interpersonal rejection sensitivity resulting in significant social or occupational impairement |
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In a person being treated for bipolar disorder at which time are they most likely to carry out suicide and which type of drug does this event occur more often in?
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Suicide is more likely to uccur during switching (going from a depressed mood to a manic episode)
Typically TCAs cause switching more often than Selective Serotonin Reuptake Inhibitors |
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What is an absolute requirement to have mania and what are some other symptoms as well?
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To have mania, you MUST have an elevated or irritable mood.
Other symptoms: Grandiosity Decreased need for sleep Increased or pressured speech Flight of ideos or racing thoughts Increased goal related activity Risk taking functional impairment |
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What is the DSM IV criteria for Manic Episode?
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Distinct period of abnormally and persistently elevated, expansive, or irritable mood lasting at least 1 week:
During mood disturbance, 3 or more fo the following DIGFAST Distractibility Indiscretion (pleasureable activities) Grandiosity Flight of Ideas Activity Increase Sleep deficit (decreased need) Talkativeness (pressure speech) |
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What are the only two mood stabilizers that prevent mania and treat depression that we learned about?
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Lamictal and Lithium
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What is the only mood stabilizer that is entirely excreted by the kidneys and not metabolized by the liver?
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Lithium
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What are the three anti-epileptic medications used to treat bipolar disorder and what are some associated side effects?
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Lamictal (lamotrigine) - only mood stabilizer that does NOT cause weight gain. Acquire Stevens Johnson Syndrome
Valproate (Depakote) - Hepatotoxicity and neural tube defects, pancreatitis, polycystic ovarian disease Carbamepazine - only drug used in psychiatry or neurology that can induce its own metabolism. Aplastic Anemia and Agranulocytosis |
