Y2B1- Pharm Anti-Arrhythmics (From Lippincott)

Front 1

DOC for atrial flutter

Back 1

Propranolol*
Verapamil*
digoxin

Starred- used first

Front 2

DOC for atrial fibrillation

Back 2

Propranolol*
Amiodarone*
anticoagulant therapy*
dofetilide

starred- used first

Front 3

DOC for AV nodal reentry

Back 3

Propranolol*
Verapamil*
digoxin

starred- used first

Front 4

DOC for acute supraventricular tachycardia

Back 4

Adenosine*
Verapamil

starred- used first

Front 5

DOC for acute ventricular tachycardia

Back 5

Lidocaine*
Amiodarone*

Front 6

DOC for ventricular fibrillation

Back 6

Amiodarone*
Epinephrine*
Lidocaine

starred-used first

Front 7

Class IA drugs

Back 7

Quinidine
Procainamide
Disopyramide

Front 8

Class IB drugs

Back 8

Lidocaine
Mexiletine
tocainide

Front 9

Class IC drugs

Back 9

Flecainide
Propafenone

Front 10

Class II drugs

Back 10

Propranolol
metoprolol
esmolol

Front 11

Class II MOA

Back 11

inhibits phase 4 depolarization in SA and AV node.

B-adrenoreceptor blocker

Front 12

Class III drugs

Back 12

Amiodarone
Sotalol
dofelitide

Front 13

Class IV drugs

Back 13

Verapamil
Diltiazem

Front 14

Class IV MOA

Back 14

inhibits action potential in SA and AV node.

Ca 2+ channel blocker

Front 15

Other anti-arrhythmics not mentioned in the classes

Back 15

digoxin and adenosine

Front 16

Pt: reversible lupus erythematosus-like syndrome

Back 16

procainamide

Front 17

Negative ionotrophic effects and Vasoconstriction

Back 17

Disopyramide

Front 18

tx: ventricular arrhythmias arising during myocardial ischemia (IE MI)

Back 18

Lidocaine

Front 19

Tx: chronic tx of ventricular arrhthmias associated with previous MI

Back 19

Mexiletine

Front 20

Tx: ventricular tachyarrhythmias, pulmonary toxicity

Back 20

Tocainide

Front 21

Tx: refractory ventricular arrhythmias; useful in suppressing premature ventricular contraction

Back 21

Flecainide

Front 22

tx: reduces incidence of sudden arrhythmic death after myocardial infarction

Back 22

Propranolol

Front 23

Tx: wide spectrum cardiac anti-arrhythmatic; reduces the risk of bronchospasm

Back 23

Metoprolol

Front 24

tx: used for in acute arrhthmias that occur during surgery or ER situations

Back 24

esmolol

Front 25

SE: hyper-, Hypo-thydroidism, photosensitivity, etc

Back 25

amiodarone

Front 26

Long term therapy to decrease rate of sudden death following an acute MI.

Back 26

sotalol

Front 27

1st line agent in pts with persistent atrial fibrillation and HF or in those with CAD w/ impaired left ventricular function

Back 27

dofelitide

Front 28

tx: better for atrial arrhythmias. Also to treat reentrant supraventricular tachycardia.

Back 28

Verapamil and dilitiazen

Front 29

tx: control ventricular response rate in atrial fibrillation and flutter

Back 29

Digoxin

Front 30

DOC for abolishing acute supraventricular hypotension

Back 30

adenosine

Front 31

Reserved for life threatening Vent Arrhyth and to resuscitate pts in V-Fib

Back 31

Bretylium

Front 32

Rapid conversions of Atrial fib or flutter to normal sinus rhythm

Back 32

Ibutilide

Front 33

Which drugs can cause torsades?

Back 33

Sotalol, procainamide, Quinidine

Front 34

WHat are the side effects of amiodarone?

Back 34

-thyroid abnormailies (hypo- and hyper-connected w high iodine content) (die to amiodaron’s structural relatedness to thyroxin
-photosensitive skin rashes
-slate grey/blue discoloration of skin (smurfism)
-pulmonary fibrosis
-corneal micro deposits
GI SE and elevated LFTs

Front 35

what class is this?

Back 35

IA

Front 36

what class is this?

Back 36

IB

Front 37

what class is this?

Back 37

IC

Front 38

What class is this?

Back 38

Class III