Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
27 Cards in this Set
- Front
- Back
|
What are the traditional preservatives for blood?
|
CPD, CP2B, this allows 21 day of RBC/Whole blood storage..
CPDA-1 allows for 35 days of rbc/whole blodo storage |
|
|
What are the additive solutions?
|
Increases shelflfe to 42 days, add to CPD, CP2D after plasma is removed. (within 72 hours), increases shelf life to 42 days
What are the common types? AS-1 As-3 AS-5 |
|
|
What are the contents of whole blood?
|
500mL
rbc's, 10^9 wbc, platelets, anticoagulant (63ml) |
|
|
When would you do this? What are contraindications?
|
neonates, some autologous, and rapid hemorrhage...
anything that is more specific would be better? |
|
|
What kind of storage time, conditions?
|
1-6C, length depends on anticoagulant
|
|
|
How long can frozen rbc's last?
|
10 years at -65C, 24 hours after thaw
|
|
|
Washed rbc's? How long?
|
24 hours 1-6 C
|
|
|
platelets? How long?
|
5 days 20-24C
|
|
|
WBC How long?
|
20-24 hours (20-24C)
|
|
|
FFP(how long)
|
1 year, -18C, 24 hours at 1-6 C after thaw
|
|
|
Cryo (how long)
|
1 year at 18 C, 6 hours at 20-24 C
|
|
|
How are PRBC's made?
|
Made from whole blood by removing the plasma?
|
|
|
What is the volume, contents?
|
250mL, 350mL with additive
rbc (200mL), plasma 50mmL, wbc's 10^8, and platelets, anticoagulant, additive solution, 200mg of iron |
|
|
What are the indictations?
|
need increased o2 capacity.
acute or chronic hemorrhage (over 20% of blood volume acutely), hemolysis, and marrow failure. consider for hemoglobin between 7 and 10 and signfificant cardiopulmonary disease. |
|
|
What are contraindications?
|
Acute hemorrhage that is less than 20% of the blood volume, crystalloids.
|
|
|
What are contraindications for prbc?
|
usually over 30, nutritional anemia
|
|
|
How long can prbc transfusion take for expected effect?
|
up to 24 24 hours?
|
|
|
What is the storage for prbc?
|
Same for whole blood with cpd, cpda-1.
|
|
|
What are compatable fluids? with prbc
|
saline, abo compatable plasma, albumin.
contraindictation, LR, 0.45, abx, other drugs, tpn |
|
|
What are the contents of PC?
|
5.5x10^10 in 90%.. plasma (including 80mg of fibrinogen), WBC's, 10^7
|
|
|
When do you transfuse platelets?
|
10K, 20K if febrile of septic, 50K if bleeding or major surgery, no prophylactic transfusion
thrombocytopathy congenital defects, drugs, external agents, cardiac bypass machine, ecmo metabolic effects |
|
|
What are contraindications to platelet transfusion?
|
ttp (abdolute), HIT (type II) (near absolute), ITP (relative)
|
|
|
What is the dose of you give in infants?
|
usually 1 unit per 10 kg of body weight.. typcially 6-10 at a time in adults.. 10-15mL of kg in neonates
|
|
|
What are the expected effects?
|
5-10K per page?, one hour post count
|
|
|
What antigens are present on platelets?
|
ABO but not Rh antigens are present on platelets. May have some RH contaminatsion.
|
|
|
When/how shoudl you do platelets transfusion?
|
Rh prophylaxis with Rh incompatability (1 vial RhIG per 30 units RH+ PC; 1 per 3 Rh+ apheresis units)
|
|
|
What's the difference between major and minor transfusion reaction?
|
Major: platelet abo antigens incompatable with recipient plasma (like a plts to o recip)
minor its the donor abo antibiodies incompatable with recipeient rbc's.. (reverse hemolytic transfusion reaction) |
