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25 Cards in this Set

  • Front
  • Back
what is the function of mitochondria:
transform chemical energy metabolites into energy that is easily accessible to the cell
what is the most important site for ATP production?
mitochondria
identify the labeled structures:
(see figure)
the mitochondria is a double membrane organelle with it's inner membrane thrown into folds called ... and the
cytoplasm internal to the folds is called the ...
cristae
matrix
outer membrane contains specialized transport proteins such as ... that allow free permeability to molecules up to about 10 kDa molecular weight from the cytosol into the ...
porin
intermembranous space
inner membrane is highly (permeable/impermeable) to small ions
impermeable
inner membrane has a high content of the phospholipid ...
cardiolipin
what is the function of the tom (translocators of the outer membrane) complex in the mitochondria:
the machinery in the outer membrane of the mitochondria that allows for transport across the outer membrane
what is the function of the tim (translocator inner membrane)
the machinery in the inner membrane of the mitochondria that allows for transport across the inner membrane
what is the function of hsp70 in the role of transport across the mitochondrial membranes:
hsp70 stabilizes proteins and helps to keep them uncoiled so they can go through tim and tom
In certain regions, the outer and inner mitochondrial membranes contact each other; these contact sites act as pathways for proteins and small molecules to enter and leave the intermembranous space or the matrix. these areas are where ...
tim and tom come together
what is the role of tiny tim chaperones:
act as chaperones to guide unfolded inner membrane proteins across the aqueous intermembrane space
what is the function of cardiolipin in the inner membrane
it renders the inner membrane virtually impermeable
Inner membrane contains enzymes of ... and the ... systems, as well as the enzyme ...
oxidative phosphorylation
electron transport
ATP synthetase
cells with mitochondria that have more cristae will have a ... energy requirement
higher
what does the matrix contain:
1.
2.
3.
4.
citric acid cycle enzymes
stored ions (ca++,etc)
DNA/RNA
phospholipoprotein
mitochondrial DNA codes for ... proteins ... tRNAs and ... rRNAs
13
22
2
In steroid hormone-secreting cells such as those of the adrenal cortex, the cristae are ... structures rather than flat plates.
tubular
The average life span of a
mitochondrion is about ... days
10
in reference to Mitochondrial Cytopathy Syndromes:
When the inheritance is Mendelian, there is a defect in ... and inheritance of these disorders can be passed to a child by ... when the defect is within the genes of the mitochondria, these disorders can only be passed to a child by the ...
nuclear DNA
both parents
mother
what does this image detect:
paracrystalline inclusions (PCI) are present, that are thought to be composed of excess mitochondrial protein which accumulates as a result of a genetic abnormality
what is the function of the associated enzymes in the outer membrane of the mitochondria:
lipid synthesis
fatty acid metablolism
what is the function of the associated enzymes in the inner membrane of the mitochondria:
ATP production
what is the function of the associated enzymes in the matrix of the mitochondria:
TCA cycle
what is the function of the associated enzymes in the intermembranous spaced of the mitochondria:
nucleotide phosphorylation