Wsu Som Unit 4 Pogue

Front 1

Important treatment administration considerations for bacterial meningitis?

Back 1

IV therapy, bactericidal

Front 2

Common bacterial meningitis pathogens in neonates (<1 month) and why?

Back 2

S. agalactiae, E. coli, L. monocytogenes, Klebsiella; do not have intact BBB

Front 3

Empiric therapy for bacterial meningitis pathogens in neonates (<1 month) and why?

Back 3

Ampicillin + cefotaxime; CTX contraindicated in neonates

Front 4

Bacterial meningitis bugs common in 1-23 months of age?

Back 4

S. agalactiae, E. coli, S. pneumoniae, H. influenza, N. meningitidis

Front 5

Treatment for bacterial meningitis in 1-23 months of age?

Back 5

Vancomycin + 3rd gen ceph

Front 6

Why is vanco added for treatment of bacterial meningitidis?

Back 6

For possible increased MIC and decreased BBB penetration of cephs

Front 7

Common bacterial meningitis pathogens in 2-50 year olds?

Back 7

N. meningitidis, S. pneumoniae

Front 8

Treatment for bacterial meningitis in 2-50 year olds?

Back 8

Vancomycin + 3rd gen cephs (+ dexamethasone)

Front 9

Function of dexomethasone treatment in bacterial meningitis?

Back 9

Decrease inflammation in subarachnoid space

Front 10

When should dexamethasone treatment be administered?

Back 10

Prior to antibiotics

Front 11

Common bacterial meningitis pathogens in persons over 50?

Back 11

S. pneumoniae, N. meningitidis, L. monocytogenes, gram negatives

Front 12

Treatment for bacterial meningitis in persons over 50?

Back 12

Vancomycin + 3rd gen ceph + ampicillin

Front 13

Duration of therapy for bacterial meningitidis?

Back 13

7-21 days (usually 14)

Front 14

Prophylaxis for N. meningitidis?

Back 14

Ciprofloxacin or rifampin

Front 15

Prophylaxis for H. infuenzae?

Back 15

Rifampin

Front 16

Common bugs in CSF shunt infections?

Back 16

Gram negative staph, or staph aureus

Front 17

Treatment for CSF shunt infections?

Back 17

Vancomycin + cefepime or piperacillin/tazobactam

Front 18

Treatment of cyptococcal meningitis?

Back 18

AmphoB + flucytosine then fluconazole

Front 19

Treatment of blastomyces, histoplasmosis CNS infection?

Back 19

AmphoB then oral azole (12 months)

Front 20

Majority of acute bronchitis infections?

Back 20

Viral

Front 21

Treatment for B. pertussis causing acute bronchitis?

Back 21

Azithromycin (macrolide), or tetracyclines or TMP/SMX

Front 22

When COPD is exacerbated, which patients are treated?

Back 22

Patients with increased dyspnea, increased sputum volume, or increased sputum purulence*

Front 23

Exacerbated COPD treatment in patients with risk factors for poor outcome?

Back 23

IV ampicillin/sulbactam

Front 24

Risk factors for P. aeruginosa infection with COPD exacerbation?

Back 24

Oral fluoroquinolones

Front 25

Duration of treatment for COPD exacerbation?

Back 25

Until clinical improvement, 3-7 days usually

Front 26

Treatment for sinusitis that has persisted for more than ten days, has severe symptoms, or has gotten worse?

Back 26

Ampicillin/sulbactam

Front 27

CAP pathogens?

Back 27

S. pneumonia, H. influenza, M. catarrhalis, M. pneumoniae, C. pneumoniae, L. pneumophila; S. aureus, oral anaerobes

Front 28

Treatment of CAP in healthy patient?

Back 28

Azithromycin (macrolide), or doxycycline

Front 29

Treatment of CAP with comorbidities, immunosuppression, or recent antibiotic exposures?

Back 29

B-lactam + macrolide

Front 30

Treatment of CAP for inpatient non-ICU?

Back 30

3rd gen ceph + macrolide

Front 31

Treatment of CAP for inpatient ICU?

Back 31

IV 3rd gen ceph + macrolide

Front 32

Treatment of aspiration pneumonia?

Back 32

Clindamycin (oral anaerobes)

Front 33

Duration of CAP treatment?

Back 33

Minimum 5 days, afebrile 48-72 hours, no more than 1 CAP related sign

Front 34

Need to cover with HAP, etc.?

Back 34

P. aeruginosa, S. aureus

Front 35

Empiric therapy for HAP?

Back 35

Antipseudomonal B-lactam + antipseudomonal FQ or AG + vancomycin or linezolid

Front 36

Why two antipseudomonals in empiric treatment of HAP?

Back 36

Resistance

Front 37

Historical duration of therapy for HAP?

Back 37

14-21 days

Front 38

Duration of treatment if HAP not caused by pseudomonas or acinetobacter?

Back 38

8 days

Front 39

Possible cause of nosocomial pneumonia?

Back 39

S. maltophilia

Front 40

Treatment of S. maltophilia?

Back 40

TMP/SMX

Front 41

Special about antibiotic dosing for CF patients?

Back 41

High dose due to extremely high metabolism rate

Front 42

Problem with Influenza treatment?

Back 42

High resistance