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12 Cards in this Set
- Front
- Back
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Fetal red blood cells
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Larger
Higher O2 affinity Shorter lifespan |
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Premature babies and iron
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Risk of iron deficiency
Don't have red blood cell iron storage pool |
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Physiologic anemia of newborn
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After birth, experience O2 rich environment
-bone marrow stops making RBC -Hb drops to 14-10 -Normal -8-10 weeks of age -For premature babies, physiologic anemia is more rapid and dips deeper |
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ABO vs Rh incompatibility
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ABO
-mom is O, baby is A or B -mom has antibodies -antibodies usually IgM that doesn't cross placenta -if there is an infection, IgG antibodies are formed and can cross placenta -not as severe as Rh disease -manifests as prolonged jaundice -can test with Coomb's test, not always positive (Rh is always positive) |
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Hereditary spherocytosis
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RBC membrane problem
Membrane gets pulled off and loses surface area Membrane loses shape Can't travel as efficiency Presents in newborn as jaundice and anemia |
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Internal hemmorhages
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Cephalohematoma
-during birth |
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Iatrogenic blood loss
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Lose blood through testing
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Newborn anemia symptoms
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Just sleeping
Can't stay awake long enough to eat |
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Spherocytosis symptoms
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Jaundice
Chronic anemia -poor growth -fatigue Gall stones Aplastic crisis -bone marrow doesn't respond to erythropoiten |
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Transient erythroblastopenia of childhood
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Aplastic crisis in otherwise normal children
Parvo B19 |
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Diamond Blackfan anemia
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Pure RBC aplasia
Congenital Low reticulocyte ~50% have other congenital abnormalities Therapy -some respond to steroids -bone marrow transplant |
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Fanconi anemia
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RBC and platelet aplasia
Therapy -bone marrow transplant |
