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82 Cards in this Set
- Front
- Back
how can we view the brain?
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with PET, MRI and CAT scans
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what are trephined skulls?
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in the past, mental illness was thought to be caused by association with an evil spirit- the skull was drilled open to allow the evil spirit to escape
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what is the brain physiologically?
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a collage of chemicals
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what is the brain spiritually?
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the brain has an invisible entity called the mind. the mind is not the same as the brain
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who is Joseph Gall?
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thought he could diagnose a mental problem by examining the skull of the patient.
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what is phrenology?
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theory: the shape of the skull reflects what is inside of the skull
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who is Johann gaspar spurzheim?
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popularized the idea of phrenology- would give lectures on the ideas central to the science of phrenology
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who is sir arthur conan doyle?
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an ophthalmologist who depicted sherlock holmes as having a large forehead. he also believed in fairies
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what was the psychograph?
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an automated method by which bumps could be measured and mapped out on an individual's head- exhibited at movie theatres. at the end of the measurement, the individual would receive a score card which explained the measurements and quantified the various characteristics that the given individual was thought to have.
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what concept did phrenology introduce?
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the fact that different parts of the brain had different purposes and performed different processes
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who was phineas gage?
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a foreman working on the railroad line who accidentally propelled an iron rod through his head. after the accident, his personality dramatically changed- he became abusive and very coarse.
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who was dr. walter freeman?
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one of the pioneers of brain science. he initiated brain surgery- believed that blocking out certain parts of the brain can hold a certain therapeutic effect. he experimented on people and discovered that mental illness could be improved via brain surgery
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Rose-Marie Kennedy...
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was lobotomized through the nose
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what was special about einstein's brain?
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it had a thicker lateral sulcus than the average person
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how do nerve cells communicate with eachother?
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chemicals are transmitted through the synapse (the region in which the axon of one neuron comes into proximity t the dendrites of another axon but d not touch)
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what does the axon do?
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it carries the signal from a particular neuron
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what does the dendrite do?
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pick up signals from other neurons
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what are neurotransmitters synthesized from?
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molecules that are derived from food
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where are neurotransmitters stored?
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in vesicles within the pre-synaptic cell
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what happens when the function of neurons is hindered or altered?
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the individual may develop a disease
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what is alzheimers?
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a disorder that gradually destroys the ability to reason, remember, imagine and learn
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what is alzheimers marked by?
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abnormal clumps (plaques) and irregular knots of brain cells
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what is the incidence of alzheimers?
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affects 1 in 10 over age 65, 1 in 2 over 85
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why is the incidence of alzheimers increasing?
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because people are living longer
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what conditions lead to dementia?
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vitamin B deficiency, impaired circulation (will cause lack of nutrients in the brain), hypothyroidism, tumors
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what is the major cause of dementia?
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alzheimers (but not only cause)
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who discovered alzheimers and when?
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alois alzheimer in 1901
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in alzheimers disease, what causes the neurofibrillary tangles?
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deposits of protein inside cells, and amyloid plaques develop between the cells
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what is one of the first signs of alzheimers?
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the ability to differentiate smells
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what is the cause of alzheimers
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aluminum was believed to be, as it is abundant in the tangles and desposts found in affected individuals, but this is not proven to be scientific evidence.
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what kind of personality is less likely to develop alzheimers?
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neat, hard-working and punctual
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in the study with nuns, which ones were the most likely to develop alzheimers?
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nuns with the lowest density of ideas per paragraph
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what can we do to prevent alzheimers?
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prevent ministrokes, folic acid, flavone, ibuprofen, anti-inflammatory, omega-3, premarin, education, reduce obesity
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what are ministrokes?
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momentary ceasing of blood flow to the brain, causing deletion of certain parts of the brain due to lack of oxygen. can be prevented by controlling blood pressure and cholesterol
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what is folic acid?
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vitamin B. intake of this can reduce dementia
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what is flavone?
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a class of molecules found in a large variety of fruits and vegetables believed to reduce incidence of alzheimers.
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how can deposits of alzheimers cause inflammation?
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the body can perceive the deposits as being foreign
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why does India have a low incidence of alzheimers?
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Turmeric is eaten in India, which contains circumin which as anti-inflammatory properties
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why is fish an anti-disease agent in alzheimers?
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it contains omega-3 fats which reduce inflammation, but also contains mercury which is bad
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what does the mediterranean diet focus on?
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grains, fruits and vegetables, avoids consumption of fats in red meat and sugars in sweets
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what is premarin?
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an estrogen that is taken by menopausal women to reduce symptoms associated with menopause. predisposes women to alzheimers EXCEPT for women who are taking testosterone at the same time.
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why is obesity linked with alzheimers moreso in women?
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women gain weight in their ass and legs, men accumulate it in their torso area
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what can be done to people who suffer alzheimers?
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music, cholinesterase inibitors, glanatamine, paroxetine, seratraine, hyperzine
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what are cholinesterase inhibitors?
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drugs that interfere with the enzyme that breaks down acetylcholine, a neurotransmitter that is short in supply in alzheimer's patients. by reducing activity of enzymes that degrade neurotransmitters, a higher frequency of information transmission is achieved- this can help slow progression of disease symptoms
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what are tacrine and donepezil?
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examples of cholinesterase inhibitors. these drugs only "buy you time" but cannot reverse progression of the disease
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how does galantamine work?
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blocks excess glutamate activity, but its not approved by the FDA
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what do paroxetine and seratraline do?
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treat depression which is associated with alzheimers
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how are agitation and delusions treated?
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haloperidol, risperidone, quetiapine
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what is huperzine?
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a chinese herbal medicated extracted from a plant whose structure is similar to acetylcholine- stimulated acetylcholine transmission
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what is parkinsons disease?
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a neurological disease that is due to a short supply of dopamine, get shaking symptoms and total immobalization eventually occurs
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what is premarin?
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an estrogen that is taken by menopausal women to reduce symptoms associated with menopause. predisposes women to alzheimers EXCEPT for women who are taking testosterone at the same time.
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why is obesity linked with alzheimers moreso in women?
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women gain weight in their ass and legs, men accumulate it in their torso area
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what can be done to people who suffer alzheimers?
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music, cholinesterase inibitors, glanatamine, paroxetine, seratraine, hyperzine
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what are cholinesterase inhibitors?
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drugs that interfere with the enzyme that breaks down acetylcholine, a neurotransmitter that is short in supply in alzheimer's patients. by reducing activity of enzymes that degrade neurotransmitters, a higher frequency of information transmission is achieved- this can help slow progression of disease symptoms
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what are tacrine and donepezil?
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examples of cholinesterase inhibitors. these drugs only "buy you time" but cannot reverse progression of the disease
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how does galantamine work?
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blocks excess glutamate activity, but its not approved by the FDA
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what do paroxetine and seratraline do?
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treat depression which is associated with alzheimers
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how are agitation and delusions treated?
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haloperidol, risperidone, quetiapine
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what is huperzine?
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a chinese herbal medicated extracted from a plant whose structure is similar to acetylcholine- stimulated acetylcholine transmission
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what is parkinsons disease?
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a neurological disease that is due to a short supply of dopamine, get shaking symptoms and total immobalization eventually occurs
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is there a cure for parkinsons?
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no.
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what is the drug used to fight parkinsons?
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sinemet- breaks down into dopamine, loses its efficiency after a few years
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why will taking dopamine orally not work in curing parkinsons disease?
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it will not cross the blood brain barrier and thus not be absorbed into the brain.
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what is multiple sclerosis (MS)?
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nerve cells become disease. when myelin sheath is damaged, nerve transmission is compromised.
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is there a cure for MS?
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no
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what substances in the environment can interfere with nerve cell function?
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mercury, lead
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how is mercury released into the air?
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burning coal, washed down by rain into the water, eaten by fihs which we then eat
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how is lead released into the environment?
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as water flows through aqueduct pipes, it dissolved some of the lead, which got into the water, some wine cups made out of lead
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what is the 10% myth?
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a myth that entails we only use 10% of our brain, and if we could learn to use the rest of it we would be much smarter
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who is uri geller?
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a magician backing up teh 10% myth, who tricked people into believing he could bend metal with his mind.
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who is dr. michael persinger?
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exposes human brains to very strong magnetic fields, and is able to trigger visions in peoples minds. he has developed a helmet with mgnets in specific places that can be activated to trigger specific visions
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what is transcranial direct current stimlation?
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a technique that uses electrodes on the head. can trigger different thoughts and is similar to shock therapy
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what really happens with the placebo effect?
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endorphins are released- thoughts can trigger the release of these endorphins
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what is good brain food?
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fish due to omega-3 acids
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why are omega-3 fats so good?
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it prevents beta-amyloid deposits. once it gets into the bloodstream it attaches to 2 hydroxy groups allowing it to become a neuroprotecti
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how much omega 3 acid should one consume during pregnancy?
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1000 mg of omega-3 per day
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what are alternatives to fish if you want to consume omega -3?
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caviar, light tuna, alpha-linolenic, nuts,
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what is so good about folic acid?
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55% deduction risk in developing alzheimers, memory and processing spped is improved
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what are good sources of folic acid?
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chickpeas, spinach, fruit, dietary supplements of folic acid
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what are other sources of brain improvement?
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ginko biloba (increases cerebral circulation) sage (good for memory) exercising your brain (puzzles, chess, bridge- improve circulation)
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what is neuroplasticity?
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the capability of the brain to make connections and forge links
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what did research show about milk chocolate?
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people eating milk chocolate improved cognitive performance, but bad in terms of cardiovascular disease.
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