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82 Cards in this Set

  • Front
  • Back
how can we view the brain?
with PET, MRI and CAT scans
what are trephined skulls?
in the past, mental illness was thought to be caused by association with an evil spirit- the skull was drilled open to allow the evil spirit to escape
what is the brain physiologically?
a collage of chemicals
what is the brain spiritually?
the brain has an invisible entity called the mind. the mind is not the same as the brain
who is Joseph Gall?
thought he could diagnose a mental problem by examining the skull of the patient.
what is phrenology?
theory: the shape of the skull reflects what is inside of the skull
who is Johann gaspar spurzheim?
popularized the idea of phrenology- would give lectures on the ideas central to the science of phrenology
who is sir arthur conan doyle?
an ophthalmologist who depicted sherlock holmes as having a large forehead. he also believed in fairies
what was the psychograph?
an automated method by which bumps could be measured and mapped out on an individual's head- exhibited at movie theatres. at the end of the measurement, the individual would receive a score card which explained the measurements and quantified the various characteristics that the given individual was thought to have.
what concept did phrenology introduce?
the fact that different parts of the brain had different purposes and performed different processes
who was phineas gage?
a foreman working on the railroad line who accidentally propelled an iron rod through his head. after the accident, his personality dramatically changed- he became abusive and very coarse.
who was dr. walter freeman?
one of the pioneers of brain science. he initiated brain surgery- believed that blocking out certain parts of the brain can hold a certain therapeutic effect. he experimented on people and discovered that mental illness could be improved via brain surgery
Rose-Marie Kennedy...
was lobotomized through the nose
what was special about einstein's brain?
it had a thicker lateral sulcus than the average person
how do nerve cells communicate with eachother?
chemicals are transmitted through the synapse (the region in which the axon of one neuron comes into proximity t the dendrites of another axon but d not touch)
what does the axon do?
it carries the signal from a particular neuron
what does the dendrite do?
pick up signals from other neurons
what are neurotransmitters synthesized from?
molecules that are derived from food
where are neurotransmitters stored?
in vesicles within the pre-synaptic cell
what happens when the function of neurons is hindered or altered?
the individual may develop a disease
what is alzheimers?
a disorder that gradually destroys the ability to reason, remember, imagine and learn
what is alzheimers marked by?
abnormal clumps (plaques) and irregular knots of brain cells
what is the incidence of alzheimers?
affects 1 in 10 over age 65, 1 in 2 over 85
why is the incidence of alzheimers increasing?
because people are living longer
what conditions lead to dementia?
vitamin B deficiency, impaired circulation (will cause lack of nutrients in the brain), hypothyroidism, tumors
what is the major cause of dementia?
alzheimers (but not only cause)
who discovered alzheimers and when?
alois alzheimer in 1901
in alzheimers disease, what causes the neurofibrillary tangles?
deposits of protein inside cells, and amyloid plaques develop between the cells
what is one of the first signs of alzheimers?
the ability to differentiate smells
what is the cause of alzheimers
aluminum was believed to be, as it is abundant in the tangles and desposts found in affected individuals, but this is not proven to be scientific evidence.
what kind of personality is less likely to develop alzheimers?
neat, hard-working and punctual
in the study with nuns, which ones were the most likely to develop alzheimers?
nuns with the lowest density of ideas per paragraph
what can we do to prevent alzheimers?
prevent ministrokes, folic acid, flavone, ibuprofen, anti-inflammatory, omega-3, premarin, education, reduce obesity
what are ministrokes?
momentary ceasing of blood flow to the brain, causing deletion of certain parts of the brain due to lack of oxygen. can be prevented by controlling blood pressure and cholesterol
what is folic acid?
vitamin B. intake of this can reduce dementia
what is flavone?
a class of molecules found in a large variety of fruits and vegetables believed to reduce incidence of alzheimers.
how can deposits of alzheimers cause inflammation?
the body can perceive the deposits as being foreign
why does India have a low incidence of alzheimers?
Turmeric is eaten in India, which contains circumin which as anti-inflammatory properties
why is fish an anti-disease agent in alzheimers?
it contains omega-3 fats which reduce inflammation, but also contains mercury which is bad
what does the mediterranean diet focus on?
grains, fruits and vegetables, avoids consumption of fats in red meat and sugars in sweets
what is premarin?
an estrogen that is taken by menopausal women to reduce symptoms associated with menopause. predisposes women to alzheimers EXCEPT for women who are taking testosterone at the same time.
why is obesity linked with alzheimers moreso in women?
women gain weight in their ass and legs, men accumulate it in their torso area
what can be done to people who suffer alzheimers?
music, cholinesterase inibitors, glanatamine, paroxetine, seratraine, hyperzine
what are cholinesterase inhibitors?
drugs that interfere with the enzyme that breaks down acetylcholine, a neurotransmitter that is short in supply in alzheimer's patients. by reducing activity of enzymes that degrade neurotransmitters, a higher frequency of information transmission is achieved- this can help slow progression of disease symptoms
what are tacrine and donepezil?
examples of cholinesterase inhibitors. these drugs only "buy you time" but cannot reverse progression of the disease
how does galantamine work?
blocks excess glutamate activity, but its not approved by the FDA
what do paroxetine and seratraline do?
treat depression which is associated with alzheimers
how are agitation and delusions treated?
haloperidol, risperidone, quetiapine
what is huperzine?
a chinese herbal medicated extracted from a plant whose structure is similar to acetylcholine- stimulated acetylcholine transmission
what is parkinsons disease?
a neurological disease that is due to a short supply of dopamine, get shaking symptoms and total immobalization eventually occurs
what is premarin?
an estrogen that is taken by menopausal women to reduce symptoms associated with menopause. predisposes women to alzheimers EXCEPT for women who are taking testosterone at the same time.
why is obesity linked with alzheimers moreso in women?
women gain weight in their ass and legs, men accumulate it in their torso area
what can be done to people who suffer alzheimers?
music, cholinesterase inibitors, glanatamine, paroxetine, seratraine, hyperzine
what are cholinesterase inhibitors?
drugs that interfere with the enzyme that breaks down acetylcholine, a neurotransmitter that is short in supply in alzheimer's patients. by reducing activity of enzymes that degrade neurotransmitters, a higher frequency of information transmission is achieved- this can help slow progression of disease symptoms
what are tacrine and donepezil?
examples of cholinesterase inhibitors. these drugs only "buy you time" but cannot reverse progression of the disease
how does galantamine work?
blocks excess glutamate activity, but its not approved by the FDA
what do paroxetine and seratraline do?
treat depression which is associated with alzheimers
how are agitation and delusions treated?
haloperidol, risperidone, quetiapine
what is huperzine?
a chinese herbal medicated extracted from a plant whose structure is similar to acetylcholine- stimulated acetylcholine transmission
what is parkinsons disease?
a neurological disease that is due to a short supply of dopamine, get shaking symptoms and total immobalization eventually occurs
is there a cure for parkinsons?
no.
what is the drug used to fight parkinsons?
sinemet- breaks down into dopamine, loses its efficiency after a few years
why will taking dopamine orally not work in curing parkinsons disease?
it will not cross the blood brain barrier and thus not be absorbed into the brain.
what is multiple sclerosis (MS)?
nerve cells become disease. when myelin sheath is damaged, nerve transmission is compromised.
is there a cure for MS?
no
what substances in the environment can interfere with nerve cell function?
mercury, lead
how is mercury released into the air?
burning coal, washed down by rain into the water, eaten by fihs which we then eat
how is lead released into the environment?
as water flows through aqueduct pipes, it dissolved some of the lead, which got into the water, some wine cups made out of lead
what is the 10% myth?
a myth that entails we only use 10% of our brain, and if we could learn to use the rest of it we would be much smarter
who is uri geller?
a magician backing up teh 10% myth, who tricked people into believing he could bend metal with his mind.
who is dr. michael persinger?
exposes human brains to very strong magnetic fields, and is able to trigger visions in peoples minds. he has developed a helmet with mgnets in specific places that can be activated to trigger specific visions
what is transcranial direct current stimlation?
a technique that uses electrodes on the head. can trigger different thoughts and is similar to shock therapy
what really happens with the placebo effect?
endorphins are released- thoughts can trigger the release of these endorphins
what is good brain food?
fish due to omega-3 acids
why are omega-3 fats so good?
it prevents beta-amyloid deposits. once it gets into the bloodstream it attaches to 2 hydroxy groups allowing it to become a neuroprotecti
how much omega 3 acid should one consume during pregnancy?
1000 mg of omega-3 per day
what are alternatives to fish if you want to consume omega -3?
caviar, light tuna, alpha-linolenic, nuts,
what is so good about folic acid?
55% deduction risk in developing alzheimers, memory and processing spped is improved
what are good sources of folic acid?
chickpeas, spinach, fruit, dietary supplements of folic acid
what are other sources of brain improvement?
ginko biloba (increases cerebral circulation) sage (good for memory) exercising your brain (puzzles, chess, bridge- improve circulation)
what is neuroplasticity?
the capability of the brain to make connections and forge links
what did research show about milk chocolate?
people eating milk chocolate improved cognitive performance, but bad in terms of cardiovascular disease.