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32 Cards in this Set
- Front
- Back
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The Na+/K+ pump moves ___ out and ___ in
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Moves 3 Na+ out and 2 K+ in
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Calcium is controlled by these two pumps
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Ca2+, Mg2+ ATPase and Na+Ca+ exchanger
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DSM-IV Axis I describes
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Acute (state) disorder
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DSM Axis II describes
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Personality Disorders
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DSM Axis III describes
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general medical conditions
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DSM Axis IV describes
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Psychosocial and Environmental Stress
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DSM Axis V describes
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Assessment of Functioning
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DSM Personality Disorder name association
Cluster A Cluster B Cluster C |
Cluster A- Odd or Eccentric (schizoid)
Cluster B- Dramatic (Borderline) Cluster C- Anxious or Fearful (OCD) |
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Social Phobia Axis I is associated with what Axis II
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Avoidant
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Schizophrenia of Axis I is associated with what in Axis II
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Cluster A schizoid
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Somatoform disorders are associated with what Axis II
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Histronic from cluster B
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Bipolar disorder is associated with what Axis II
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Borderline of cluster B
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Compare N2 and N1 nicotinic receptors
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N2 are in skeletal muscle
N3 are in neurons |
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Muscarinic receptors are G protein or Ion coupled?
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G protein coupled
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Cells of the heart have what muscarinc receptor?
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M2
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Which Muscarinic receptors are typically inhibitory? Which excitatory?
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M2,4 inhibitory
M1 3 5 excitatory |
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Name two enzymes that degrade catecholamines- which is intracellular, extracellular?
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Monoamine oxidase is intracellular
Catechol o methytransferase is extracellular |
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These adrenergic receptors are GPCR, stimulated by norepinephrine and epinephrine, found in vascular smooth muscle, iris, GI and urinary sphincters, and are excitatory
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Alpha 1
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Which adrenergic receptor is for vasodilation in coronary arteries and vascular supply to skeletal muscle
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Beta 2
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These adrenergic receptors respond to NE and Epi, are GPRC, primarily inhibitory, and located on presynaptic nerve terminals
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Alpha 2
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Beta 1 receptor is typically excitatory or inhibitory
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excitatory, it stimulates Adenylyl cyclase activity
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Are Beta 2 excitatory or inhibitory
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mostly inhibitory, they are on most tissues and lead to relaxation of smooth muscle
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What are the two major projection systems in the CNS of Ach
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Reticular activating- cell bodies in the pedunculopontine tegmental region
Basal forebrain in the nucleus basalis Also cholinergic interneurons in striatum |
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Noradrenergic neurons are located in the
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locus coeruleus part of the reticular activating system
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Dopamine cell bodies are present in the midbrain including (3)
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substantia nigra, ventral tegmental area, retrorubral field
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between MAO a and b which has a higher affinity for dopamine
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MAOb
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Does the thalamic reticular nucleus use glutamate?
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no. it is exclusively GABA
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Is glycine excitatory or inhibitory?
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Inhibitory
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What is reversal potential?
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The equilibrium potential for a single ion
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What is the DBS target for dystonia
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Thalamus VIM
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What is the target of DBS for an essential tremor?
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VIM
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What is stimulated for OCD in DBS?
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AC-IC
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