Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
71 Cards in this Set
- Front
- Back
Hemiballismus shows what clinical features and which side in relation to lesion
|
wild flinging movements of extremities contralateral to lesion in the basal ganglia
|
|
This motor system runs throughout the entire cord
|
lateral corticospinal tract
|
|
Main branches of internal carotid include
|
Opthalamic
Posterior Communication Anterior choroidal Anterior Cerebral Middle Cerebral |
|
The cortex on the medial surface from the frontal to anterior parietal lobes including the medial sensorimotor cortex is supplied by what artery?
|
Anterior Cerebral Artery
|
|
The cortex on the lateral frontal lobe is typically supplied by (does most of the dorsolateral part of the brain)
|
The Middle Cerebral Artery
|
|
The inferior medial temporal lobes and occipital cortex is supplied by what artery?
|
The posterior cerebral
|
|
In the saggital fissure and around the cingulate gyrus the blood supply is from?
|
A2 a branch of the Anterior Cerebral Artery
|
|
Deep nuclei in the brain are supplied by which artery
|
MCA
|
|
The caudate and putamen are supplied by what arteries?
|
The head of the caudate and anterior part of the putamen- ACA
the body of the caudate and putamen- MCA the tail of the caudate- Anterior Choroidal |
|
The basal ganglia and internal capsule get blood supply in general from this branch
|
lenticulostriate from the MCA
|
|
Territory of the Anterior Choroidal artery includes
|
globus pallidus, putamen, thalamus, and posterior limb of internal capsule
|
|
A lacunar infarct in either the lenticulostriate or anterior choroidal causes
|
contralateral hemiparesis
|
|
The anterior head of caudate and the nucleus accumbens is supplied with blood from
|
Recurent Artery of Hubner
|
|
The posterior limb of the internal capsule is supplied by
|
Anterior Choroidal Artery
|
|
The Anterior Choroidal Artery is a branch of
|
direct branch of the ICA
|
|
Structures in the diencephalon like the thalamus and hypothalamus are supplied by this artery
|
Posterior Cerebral
|
|
The calcarine fissure or primary visual cortex gets blood supply from
|
PCA
|
|
Axons of the optic nerve from both eyes synapse _laterally on pretectal neurons in the ____
|
bilaterally on pretectal neurons in the superior colliculus of midbrain
|
|
CN III exits the ventral brainstem in the ___ by which two arteries?
|
Interpeduncular fossa
SCA and PCA |
|
Oculumotor palsy and damage to motor of consensual light reflex could be from an aneurysm to which arteries
|
SCA and PCA
|
|
A Marcus-Gunn pupil describes
|
An afferent pupillary defect where the eye will fail to constrict when light stimulus is applied but will react consensual with light in good eye
|
|
A pupillary constriction response that is markedly less to light stimulation than accomodation is called
|
A light-near dissociation or an Argyl Robertson pupil
|
|
3 classic signs of Horner's Syndrome
|
ptosis, miosis, and anhidrosis
|
|
Ansicoria means
|
pupillary asymmetry
|
|
Does an UMN or LMN lesion spare the forehead?
|
UMN
|
|
UMN lesions that affect the face present as
|
contralateral weakness below forehead
|
|
A lesion of one of these 2 pathways would caused decreased corneal reflex
|
trigeminal sensory, facial nerve on ipsilateral eye
|
|
Right face, arm, and leg weakness with hyperrflexia and Babinski sign most likely represents damage to
|
the Left Corticobulbar and Corticospinal tract of the internal capsule
|
|
Major ouput nuclei of the basal ganglia circuitry (2)
|
Globus Pallidus Internal and Substantia Nigra pars Raticulata
|
|
Stimulating GPi will result in
|
a decrease of motor activity
|
|
Prominent portion of the striatum for planning and revising motor plans
|
Putamen
|
|
What projects dopamine to the striatum
|
substantia nigra
|
|
Neurotransmitter used by GPi
|
GABA
|
|
In the Direct pathway dopamine works on (D1 or D2 receptors) on spiny neurons in putamen that use (substance P or enkephalin) along with GABA
|
Direct Pathway is D1 receptors and Substance P with GABA
|
|
Why does loss of SNc neurons cause Parkinson's clinical features?
|
Snc uses dopamine, without dopamine the direct pathway cannot be stimulated to make movement
|
|
Indirect pathway uses substance P or enkephalin with GABA
|
enkephalin with GABA
|
|
Stimulation of STN on the GPi is normally restrained by
|
GPe
|
|
How is the indirect pathway inhibited in normal conditions
|
Dopamine from SNc binds D2 receptors and inhibit their firing
|
|
At the onset of Parkinson's is dementia evident?
|
No. it may come about later but not always
|
|
Why is carbidopa given with levodopa?
|
Carbidopa is a decarboxylase inhibitor that cannot cross blood/brain barrier, it ensures that dopamine only goes to CNS and not periphery
|
|
This drug works by inhibiting the breakdown of dopamine
|
selegiline
|
|
Patient with involuntary wild flinging movement in the right arm and leg likely has what clinical syndrome and where is the lesion
|
likely hemiballismus
Problem with the indirect pathway, clinical localization- left STN or straitum |
|
What region of the brain are the nuclei for CN III IV and VI
|
CN III and IV are in the midbrain
CN VI is in the caudal pons |
|
When the eye is ADDucted what pulls the eye up and down
|
Superior and Inferior Oblique
|
|
When the eye is ABDucted what pulls the eye up and down
|
Superior and Inferior Rectus
|
|
Findings in occulomotor palsy
Eye position Eyelids Pupil |
Eye is down and out
Eyelid droops because lavetor palpebrae is denervated Pupil is Dilated and unresponsive |
|
Occulomotor palsy may result from aneurysm in which artery?
|
PComm
|
|
A painful occulomotor palsy that involves the pupil is a classic sign of
|
aneurysm
|
|
Verticle diplopia that worsens when the eye is Adducted is a sign of
|
Trochlear Nerve Palsy
|
|
In right trochlear nerve palsy the head is usually tilted
|
down and to the left
|
|
Horizontal diplopia is a sign of
|
Abducens palsy
|
|
Pontine infarcts can cause ipsi or contra lateral problems with the abducens
|
ipsilateral
|
|
Cortical injury can impair eye movement in ___ direction resulting in gaze preference ___ the side of injury
|
impair movement in contralateral direction, gaze is toward the side of injury and away from the side of paralysis
|
|
Right way eyes describe
|
eyes move away from paralyzed side toward the cortical injury
|
|
A lesion of the pons hits the gaze center ipsilateral or contralateral and the lateral cortical spinal tract before or after decussation
|
ipsilateral, before decussation
|
|
Describe wrong way eyes
|
eyes move toward the paralyzed side away from the brainstem injury
|
|
Fast phase saccades are distrubed by lesions in th
|
frontal cortex
|
|
CN III exits ___
|
Ventral midbrain
|
|
CN V exits
|
Ventral Pons
|
|
CN VI VII VIII exit
|
Pontine/Medullary junction
|
|
CN IX X XI XII exit
|
ventral medulla
|
|
In the ventricles the anterior horn extends into the
|
Frontal Lobes
|
|
The posterior horn of the ventricles extends into the
|
occipital lobe
|
|
The inferior horn of the lateral ventricle extends into the
|
temporal lobe
|
|
A weigert stain stains ___ black
|
stains myelin fibers black so gray matter is left a lighter shade of gray
|
|
Spinal trigeminal nucleus is located and conveys what information
|
Located in medulla and caudal pons
relays pain |
|
The Cheif Trigeminal is located __ and conveys what information
|
located in the middle of the pons, relays vibration
|
|
The trigeminal motor nucleus is medial or latreal to the principal
|
medial
|
|
Where is the mesencephalic nucleus located and what does it relay
|
located in midbrain
not a relay nucleus these synapse to convey proprioception |
|
Axons of retinal cells involved in pupillary light reflex enter what part of the brainstem and where do they terminate
|
Superior Colliculus
terminate at pretectal nucleus |
|
Are seizures a problem with cortex subcortex brainstem or cerebellum
|
Cortex
|