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15 Cards in this Set

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What are the general features of inflammation?
Rubor (redness) Calor (heat)
Tumor (swelling) Dolor (pain)
Functio lasea (loss of function)
What often causes the redness and heat associated with inflammation?
vasodilation(increased blood flow to the site of injury)
Why is edema often experienced with inflammation?
vessell has increased permeability causing exudate
What does histamine do?
causes dialation of arterioles and increased permiability of venules
How is histamine released?
mast cell degranulation releases histamine
What causes mast cell degranulation?
injury, anaphylotoxins, chemokines, substance P
What is Lewis' Triple Response?
Flush: capillary dilatation (vasodilation)
Flare: arteriolar dilatation (vasodilation)
Weal: exudation, edema (Increased capillary permeability)
Where is nitric oxide produced?
endothelial cells, neurons, phagocytes
What is chemotaxis?
Leukocytes follow towards the site of injury in the tissue along a chemical gradient of chemo-attractants
What is transudate?
result of hydrostatic
or osmotic imbalance
ultrafiltrate of plasma
Low protein content
What is exudate?
result of inflammation
vascular permeability
high protein content
Describe serous inflammation
Marked by thin fluid derived from the plasma or from the secretions of mesothelial cells lining the peritoneal, pleural, and pericardial cavities. Skin blister resulting from a burn or viral infection is one such example.
Describe fibrinous inflammation
A consequence of greater increase in vascular permeability
allowing molecules like fibrinogen to pass through. Fibrinogen is converted to fibrin in the extracellular space and deposited
Where is fibrinous exudate often found?
lining of body cavities, such as the meninges, pericardium and pleura
Descrive suppurative/purulent inflammation
characterized by the production of copious amounts of pus
or purulent exudate consisting of neutrophils, liquefactive necrosis, and edema fluid