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15 Cards in this Set
- Front
- Back
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What are the general features of inflammation?
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Rubor (redness) Calor (heat)
Tumor (swelling) Dolor (pain) Functio lasea (loss of function) |
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What often causes the redness and heat associated with inflammation?
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vasodilation(increased blood flow to the site of injury)
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Why is edema often experienced with inflammation?
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vessell has increased permeability causing exudate
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What does histamine do?
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causes dialation of arterioles and increased permiability of venules
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How is histamine released?
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mast cell degranulation releases histamine
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What causes mast cell degranulation?
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injury, anaphylotoxins, chemokines, substance P
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What is Lewis' Triple Response?
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Flush: capillary dilatation (vasodilation)
Flare: arteriolar dilatation (vasodilation) Weal: exudation, edema (Increased capillary permeability) |
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Where is nitric oxide produced?
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endothelial cells, neurons, phagocytes
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What is chemotaxis?
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Leukocytes follow towards the site of injury in the tissue along a chemical gradient of chemo-attractants
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What is transudate?
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result of hydrostatic
or osmotic imbalance ultrafiltrate of plasma Low protein content |
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What is exudate?
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result of inflammation
vascular permeability high protein content |
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Describe serous inflammation
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Marked by thin fluid derived from the plasma or from the secretions of mesothelial cells lining the peritoneal, pleural, and pericardial cavities. Skin blister resulting from a burn or viral infection is one such example.
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Describe fibrinous inflammation
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A consequence of greater increase in vascular permeability
allowing molecules like fibrinogen to pass through. Fibrinogen is converted to fibrin in the extracellular space and deposited |
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Where is fibrinous exudate often found?
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lining of body cavities, such as the meninges, pericardium and pleura
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Descrive suppurative/purulent inflammation
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characterized by the production of copious amounts of pus
or purulent exudate consisting of neutrophils, liquefactive necrosis, and edema fluid |
