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25 Cards in this Set

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Def'n Arthritis
Joint swelling / effusion OR
2 of:
tenderness or pain on movement
limited movement
increased warmth
What are the criteria for JIA?
Onset < 16 years
Duration > 6 weeks
Exclusion!
No test
What are some exclusions for Dx of JIA?
Infectious, malignant, pain syndrome, trauma, autoimmune, etc
What are some cardinal features of joint infection?
- Fever
- pain and tenderness
- swelling
- redness
What is the definitive Dx of joint infection?
Aspirate and culture. Blood culture.
Why is it important not to Dx TB monoarthritis as JIA?
Because steroid tx will make it much worse.
What is erythema migrans? Where (geographically) are you likely to get it?
The rash associated with Lyme Disease. Northeastern United States.
A 16 year old presents with polyarthritis in hands and feet and a bright red facial rash. Dx?
Parvovirus arthritis
An 8 year old developed arthritis 2 weeks after a sore throat and fever. Dx?
Acute Rheumatic Fever secondary to strep A infection.
How long after infection does reactive arthritis usually present? What is a common cause of RA besides strep? What will culture of joint fluid show?
1- 3 weeks.
Enterics (salmonella) or viral.
Culture will show nothing: joint fluid is not infected in RA
What are some clues that an arthritis may be due to malignancy?
Fever, weight loss
Pain > findings
Night pain
HSM
Anemia
Metaphyseal lucencies on XR
What do metaphyseal lucencies specifically suggest?
Leukemia / lymphoma
When should you use steroids to treat arthritis?
When the Dx is known. Don't want to give for infectious / neoplastic causes.
What are some common causes of Hip Pain in childhood?
Age 2-6
4-10
10-14
2-6: transient synovitis following viral infection
5-10: Legg-Perthe's AVN of hip (cause unknown)
10-14: SCFE
In what group is SCFE often seen?
What is a sign of SCFE?
Older, obese boys
When asked to flex hip, will get flexion + external rotation
What group are 'growing pains' seen? Why is the name a misnomer?
3-10 years. Pain in calf, thigh, shins. No relation to growth.
What are 5 Subtypes of JIA
1. Systemic w/ fever and rash
2. Oligoarticular: <4 joints
3. Polyarticular (5 or greater) --> RF+ (rare!) or RF-ve
4. Enthesitis related arthritis
5. Psoriatic arthritis
What are some extraarticular findings on P/E and lab?
Fever, rash, HSM, lymphadenopathy
Serositis
Anemia
ESR, CRP, WBC, PLTs, IL6 all high
Why is growth inhibited in long time sufferers of JIA?
IL 6 suppresses growth
Steroid tx suppresses growth
What is the profile of a typical Oligarticular JIA sufferer?
F
<5
more common than other forms
ANA +ve
RF neg
flexion contracture and leg length discrepancy
Why should one examine the eye of someone with JIA, particular oligoarticular JIA?
Uveitis. Often asymptomatic but can lead to blindness.
Who is likely to get true RF +ve polyarticular JIA?
Older girls. Still very rare.
What is enthesitis related arthritis? Who is it more common in?
Related to tendon-bone attachments. Seen way more often in boys > 8 than girls. HLAB27 +ve. Uveitis often symptomatic.
All of the following are complications of oligoarticular JIA affecting the right knee except:
a) right thigh wasting
b). overgrowth of right leg vs left
c) right knee flexion contracture
d) an irregular shaped pupil
e) subluxation of patella
E
Management: JIA
1st line
2nd Line
3rd Line
1st line: NSAIDS + / - steroid injections
2nd line: methotrexate / sulfasalazine
3rd line: TNF antagonist (Etanercept, Infliximab)