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7 Cards in this Set

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  • Back
Neutrophils
Polymorphonuclear granulocytes
Most numerous WBC
Primarily phagocytosis. Mature phagocyte when released from bone marrow
Basophils
Fewest WBC
Mobile mast cells—continues inflammatory response
Secretes heparin, histamine, serotonin, kinins, leukotriens, & platelet activating factor
Potentiates other vasoactive substances & inflammatory mediators
Increase leukocyte adherence to & permeability through capillary wall
Induces blood clotting in damaged vessels
Eosinophil
Intermediate in #
Responsible for combating infection and parasites
Associated with allergy and asthma
Macrophages are found here...
(Reticuloendothelial system)
Mobile cells
Skin and subcutaneous tissues (histiocytes)
Lymph nodes
Lung alveoli
Liver sinusoids (Kupffer Cells)
Spleen & Bone marrow
Rasburicase (Elitek)
Recombinant form of urate oxidase
Inhibits uric acid to prevent kidney damage in Leukocytosis
Allopurinol (Aloprim, Zyloprim)
Inhibits xanthine oxidase, the enzyme that synthesizes uric acid to prevent kidney damage in Leukocytosis
Granulocyte-macrophage colony-stimulating factor (GM-CSF)—Leukine (sargramostim)

Granulocyte colony-stimulating factor (G-CSF) analog—Filgrastim
Induce proliferation of stem cells to promote more WBC
Enhance activity of leukocytes
Fever, chills, bone / joint pain