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52 Cards in this Set
- Front
- Back
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Smudge cell
Chronic Lymphocytic Leukemia |
thumbprint appearance; nuclear remnants of lymphocyte
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Basket cell
chronic Lymphocytic Leukemia |
net-like appearance
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Hypersegmented neutrophils ( macropolycytes)
Pernicious Anemia |
nucleus with 5-10 lobes |
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Vacuolated cells
chemical poisoning, severe infections and leukemia |
with holes or vacuoles in the cytoplasm of monocytes
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Lupus erythematosus cell
disseminated LE but not specific to SLE |
phagocytic wbc; ingested nuclear material
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Tart cells
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maybe seen in drug sensitivity
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Hairy cells
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small lymphocytes with cytoplasmic projections
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Ferrata cell
SBE- Sub bacterial endocarditis |
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Reider cells
CLL - Chronic Lymphocytic Leukemia |
clover leaf
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Pelger-Huet Anomaly
congenital true PHA, acquired pseudo PHA |
Pince-nez
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Dohle bodies
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in neutrophil as irreg. rounded/oval, blue staining; "Pince nez" *
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Auer bodies/ Faggot cells
acute myelocytic leukemia |
like twigs, reddish purple in cytoplasm
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Alder-Reilly anomaly
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dense azurophilic granulation in all types of wbc
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Czediak Higashi syndrome
partial albinism |
affects all wbc
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May-Hegglin anomaly
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with pale blue, spindled-shape inclusions
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Gaucher's cell
Gaucher's disease |
crinckled appearance
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Foam cells
Niemann-Pick disease |
found in BM
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Lymphocyte
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monocyte
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eosinophil
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basophil
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neutrophil
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stages
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stages of granulopoiesis
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Give the normal Values for WBC's |
5,000 - 10,000 uL |
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Give the normal Levels of Hematocrit. |
Female: 37– 46%
Male: 42 –52% |
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Give the normal Levels of Hemoglobin. |
Female: 12.3 – 15.7 g/dL
Male: 14.0 – 17.4 g/dL |
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Give the normal value of RBC's. |
Adult Female: 4.0-5.5 millions/mm3
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Give the normal Neutrophil values. |
2,500-8,000 mm3 (55-70%) |
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Give the normal values of Lymphocytes. |
1,000-4,000 mm3 (20-40%) |
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Give the normal values of Monoocytes.
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150 - 1,000/ul (3-10%) |
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Give the normal values of Basophils.
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0 - 200/ul (0-2%) |
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Give the normal values of Eosinophils.
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0 -300/ul (0-3%) |
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Give the normal values of Platelets. |
150,000 - 400,000/ul |
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These cells are increased in: Neutrophil: Lymphocyte: Monocyte: Eosinophil: Basophil: |
Neutrophil: bacterial infections Lymphocyte: viral infections Monocyte: TB, syphilis, malignancies Eosinophil: allergies, parasites, CML Basophil: immediate hypersensitivity, CML |
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Hypersegmented Neutrophil is associated with: |
Pernicious Anemia |
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Hyposegmented Neutrophil is associated with:
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Pelger Huet Anomaly, Psuedo-Pelger Huet |
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Toxic Granulation and Vacuoles are associated with: |
Bacterial infections, burns, chemotherapy |
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Dohle Bodies (RNA) are associated with: |
Bacterian infections, burns, May-Hegglin |
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Atypical Lymphs (size increase & basophilia) is associated with: |
Infectious Mononucleosis; other infections |
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Rieder cell |
Has clover leaf like nucleus; found in chronic lymphocity leukemia |
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Flame Cell |
Antibody plasma cell w/ intense eosinophilic cytoplasm; may be seen in IgA myelomas |
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Grape Cell/Motts Cell |
Cytoplasm is filled w/ Russell bodies; seen in multiple myelomas. |
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Tart Cell |
Monocyte which has ingested whole lymph. or nucleus w/ nuclear chromatin |
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Toxic granulations |
altered primary granules w/c contain myeloperoxidase; seen in chemical poisoning |
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Myeloperoxidase deficiency (MPO) |
most common antibody |
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Popcorn Cells / L & H Cells |
Seen in Nodular Lymph. Predominant Hodgkin's Lymphoma |
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Reed-Sternberg Cells |
Has an owl's eye appearance; seen in classical Hodgkins Lymphoma |
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Lacunar Cells |
Has beta nucleus; artifactual refraction of cytoplasm; seen in Nodular Sclerosis |
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Sezary Cell |
Cells of lymphocytic origin; see in Mycosis Fungoides |
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Lazy Leukocyte Syndrome |
Neutrophils that respond poorty to chemotactic agents; poor directional motiliy |
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Jordan's Anomaly |
Granulocytes and monocytes w/fat containing vacuoles; seen in ictosis & muscle dystrophy |
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Chronic Granulomatous Disease |
Phagocytes fail to produce super oxide; seen in bacterial and fungal infections |
